Aspirin Flashcards
1
Q
Aspirin uses • ACS • Coronary artery stenting • Hypertension • Acute ischaemic stroke • AF • Myocardial perfusion scan • Cardio, cerebo peripheral arterial disease
A
Aspirin uses • ACS • Acute ischaemic stroke • AF • Cardio, cerebo peripheral arterial disease
2
Q
Aspirin MOA • Increases cAMP • Block adenosine • Irreversibly inhibits COX • Prevent platelet aggregation • Decrease platelet aggregation
A
- Irreversibly inhibits COX
* Prevent platelet aggregation
3
Q
SE of aspirin • Bleeding • GI upset • GI ulcer/ haemorrhage/ disturbance • Headache, flushing dizziness • Tinnitus • Bronchospasm
A
- GI ulcer/ haemorrhage/ disturbance
- Tinnitus
- Bronchospasm
4
Q
Warning with Aspirin • Active bleeding • 3rd trimester of pregnancy • Child <16 • Aortic stenosis • Gout • Peptic ulceration
A
- 3rd trimester of pregnancy
- Child <16
- Gout
- Peptic ulceration
5
Q
Interactions • Anticoagulants • Ramipril • Antiplatelets • Adenosine • ACE inhibitor • CCB • Cytochrome p450
A
Interactions
• Anticoagulants
• Antiplatelets
