dumes Flashcards

1
Q

a premature new born is found to be tachypnoeic. On examination there is intercostal recession, nasal flaring and cyanosis. What explains the respiratory distress

A

the law of La place

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2
Q

what is the law of la place

A

the tension exterted on a spherical wall of set pressure is inversely proportional to the spheres thickness

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3
Q

boyles law

A

the volume of a gas at constant temperature varies inversely with the pressure exerted on it.

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4
Q

daltons law

A

the total pressure of a mixture of gases is equal to the sum of the partial pressures of the individual component gases

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5
Q

henrys law

A

the amount of gas that is dissolved in a liquid is directly proportional to the partial pressure of that gas above the liquid when the temperature is kept constant.

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6
Q

bohr effect

A

describes hemoglobin’s lower affinity for oxygen secondary to increases in the partial pressure of carbon dioxide and/or decreased blood pH.

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7
Q

haldane effect

A

shift in the CO2 dissociation curve caused by oxygenation of Hb.

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8
Q

what nerves carry exclusively parasympathetic nerve fibres

A

cranisal nerves II, VII, IX and X

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9
Q

normal genes that stimulate cell division

A

proto oncogenes

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10
Q

rate limiting enzyme in glycogenesis

A

glycogen synthase

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11
Q

rate limiting enzyme in glycogenolysis

A

glycogen phosphorylase

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12
Q

rate limiting enzyme in gluconeogenesis

A

fructose 1,6- biphophonate

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13
Q

rate limiting enzyme in lipogeneisis

A

glycogen phosphorylase

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14
Q

what immunoglobulin is dominant in the secondary memory immune response

A

igG

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15
Q

cMYC

A

burkitts lymphoma

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16
Q

nMYC

A

neuroblastoma

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17
Q

BCL-2

A

follicular lymphoma

18
Q

RAS

A

pancreatic cancer

19
Q

ABL

A

chronic myeloid leukaemia

20
Q

what cancer is most associated with psammoma body formation

A

mesothelioma

21
Q

what are psammoma bodies

A

collections of calcium in biopsy samples of mesothelioma

22
Q

CA -125

A

ovarian cancer

23
Q

what HPV are associated iwth cervical cancer

A

16 and 18

24
Q

what HPV causes genital warts

A

6 and 11

25
Q

how are skeletal muscle differentiated from cardiac muscle

A

by the presence of multiple, elongated nuclei found at the periphery of muscle fibres

26
Q

what muscle has a strated appearance

A

skeletal and cardiac

27
Q

skeletal muscle junctions

A

neurogenic

28
Q

malignant neoplasm of bone

A

osteosarcoma

29
Q

vagal stimulation

A

causes negative chronotropic effect on th eheart

30
Q

kidney bean shaped nucleus

A

macrophage

31
Q

responsible for destruction of large parasites which cannot be phagocytosed

A

mast cell

32
Q

sarcoidosis hypersensitivity

A

type IV

33
Q

when does hyperpolristion come as a resuly from

A

sodium channels close, K channels open

34
Q

what is a sarcoma

A

malignant connective tissue tumour

35
Q

depolaristaion during an action potential is primarily caused by what

A

influc of sodium through voltage gated ion channels

36
Q

elbow joint

A

hinge type synovial joint

37
Q

sternoclavicular

A

saddle shaped synovial joint

38
Q

intersseos membrane of the forearm

A

fibrous joint

39
Q

pubic symphysis

A

secondary cartaglinous joint

40
Q

level of the male nipple

A

t4