drugs with their classes Flashcards
morphine
heroin
hydromorphone
oxymorphone
codeine
hydrocodone
oxycodone
meperidine
fentanyl
methadone
propoxyphene
opioids
What are the three classes of opioids? what drugs are in each class?
Morphine-Like (morphine, heroin, hydromorphone, oxymorphone, codeine, hydrocodone, oxycodone)
Meperidine-Like (meperidine, fentanyl)
Methadone-Like (methadone, propoxyphene)
morphine
morphine like
heroin
morphine like opioid
hydromorphone
oxymorphone
morphine like
codeine
morphine like opioids
hydrocodone
morphine like opioids
oxycodone
morphine like opioids
meperidine
meperidine like opioid
fentanyl
meperidine like opioid
methadone
methadone like opioid
propoxyphene
methadone like opioid
What are the opioid agonists-antagonists
butorphanol
pentazocine
buprenorphine
butorphanol
opioid agonist antagonist
pentazocine
opioid agonist antagonist
buprenorphine
opioid agonist antagonist
Binds to a pain receptor but causes a weaker pain response than a full ____
Mu, Kappa, delta receptors must be receptive to drugs; mu is most important (morphine)
not used as a first line analgesic
can cause respiratory depression but not usually as bad
Headaches, nausea
increased cardiac workload
agonist
agonist antagonist pharmacologic action
Respiratory depression (limited)
Sedation, dizziness, lightheadedness, drowsiness
Headache
Nausea
Increased cardiac workload with butorphanol and pentazocine
Abstinence syndrome – have withdrawal (less severe than opioid dependent)
agonists antagonists adverse effects
Measure baseline vital signs
Ask about opioid usage
Monitor respirations, if < 12 withhold medication and stimulate breathing
Fall precautions
Consider recommending an alternative if N/V doesn’t resolve
Do not administer to patients with myocardial infarction or cardiac insufficiency
agonists-antagonists interventions
IM, IV or intranasally
Pentazocine (Talwin) is only given orally
Measure baseline vital signs before administration and monitor throughout therapy, hold if resp rate < 12
Have naloxone (Narcan) and resuscitation equipment available (hard to reverse respiratory depression)
For intranasal administration, give one spray and repeat every 60-90 minutes as needed
For preop IM administration, give 60-90 minutes before surgery
Monitor therapeutic effects
Do not discontinue abruptly
agonist antagonists administration
only use wen needed and for short a term as possible
don’t want them operating heavy machinery or tasks that require alterneess until we know how the drug works with them
fall precautions
change possibitions gradually when standing us rising
report a worsening headache
tell then to lie down when feeling nauseated
should not use this drug for chest pain because of increased cardiac output that the drug will require
do not add opioids unless the doctor has approved it
agonists-antagonists patient instructions
Analgesic, Antiinflammatory and Antipyretic Activity
Also for headaches, myalgia, neuralgia, arthralgia, postoperative pain
Relief of pain with rheumatoid arthritis, juvenile arthritis, ankylosing spondylitis, osteoarthritis, gout, hyperuricemia
NSAIDS - Indications
What are the NSAIDS?
Aspirin
Ibuprofen
Naproxen
Indomethacin
Ketorolac
GI tract
Heartburn to GI Bleeding
Acute Renal Failure (especially if dehydrated)
Due to disruption of prostaglandin function
NSAIDS block protective effects of COX-1 on the kidneys
Reye’s Syndrome
Salicylism
NSAIDS - Adverse Effects
Monitor for signs of bleeding
Test for and treat Helicobacter pylori infection
Recommend a proton pump inhibitor during NSAID therapy
Monitor I & O, BUN and Creatinine
Monitor for salicylism
With long term use of non-aspirin NSAIDS: Monitor for signs of embolic event
Recommend low dose aspirin to prevent embolic events
NSAIDS -Interventions
Aspirin
nsaid (cox 1)
Ibuprofen
nsaid (cox 1)
Naproxen
nsaid (cox 1)
Indomethacin
nsaid (cox 1)
Ketorolac
nsaid (cox 1)
Celecoxib
nsaid cox 2
What is the centrally acting nonopioid ?
tramadol
tramadol
centrally acting nonopioid prototype
Binds to selected opioid receptors and blocking reuptake of norepinephrine and serotonin in the central nervous system
Centrally Acting Nonopioid – Expected Pharmacologic Actions
Sedation, dizziness
Headache, N/V, constipation
Respiratory depression (rare)
Seizures (rare) – avoid taking if have a history of seizures
Urinary retention
centrally acting nonopioid -adverse effects
Fall precautions
Give lowest effective dose possible; short term
Give with food
Antiemetic if N/V occur frequently
Baseline vitals, monitor respirations
Administer _______ antagonist if needed to restore respiratory rate
Monitor for signs of seizure activity
Monitor for urinary retention
Centrally Acting Nonopioid - Interventions
do not give prior to driving or necessary mental alertness
dizziness: sit or lie down when you feel dizzy
change position gradually
increase fluid and fiber intake, exercise to prevent constipation
take only when needed, and for short term
report urinary retention
Centrally Acting Nonopioid – Patient Instructions
Acute intoxication with alcohol, opioids and psychotropic drugs
Seizure disorders
Respiratory depression
Children younger then 16 years old
Centrally Acting Nonopioid - Contraindications
Treat the hyperuricemia (increased uric in blood) that causes
gout
Treat hyperuricemia that occurs secondary to:
Cancer chemotherapy
Blood dyscrasias
Uricosurics - Indications
What are the uricosurics?
allopurinol
febuxostat
probenecid
febuxostat
uricosurics
allopurinol
uricosurics
probenecid
uricosurics
What are the glucocorticoids?
prednisone
hydrocortisone
methylprednisolone
prednisone
glucocorticoid
hydrocortisone
glucocorticoid
methylprednisolone
glucocorticoid
what are the benzodiazepines?
diazepam
alprazolam
lorazepam
temazepam
What is the nonbenzodiaepine anxiolytics?
buspirone
What is the nonbenzodiazepine anxiolytic?
buspirone
zolpidem
nonbenzodiazepine hypnotic/sedative
buspirone
nonbenzodiazepine anxiolytic
-pam
or alprazolam
benzodiazepines
zaleplon
new class of hypnotic,
benzo like medication
sedative/hypnotics
eszopiclone
benzodiazepine like medication
hypnotic
suvorexant
- sedative hypnotic (non Benzo)
What are the traditional antiepileptics?
phenytoin
carbamazepine
valproic acid
(remember PCV)
phenytoin
traditional antiepileptics
carbamazepine
traditional antiepileptics
valproic acid
traditional antiepileptics
what are the newer antiepileptics (anticonvulsants)?
lamotrigine
oxcarbazepine
topiramate
gabapentin
(remember LOT, G)
lamotrigine
newer antiepileptics
oxcarbazepine
newer antiepileptics
topiramate
newer antiepileptics
gabapentin
newer antiepileptics
What are the SSRI’s?
paroxetine
fluoxetine
sertraline
paroxetine
SSRI
fluoxetine
SSRI
sertraline
SSRI
What are the SNRIs?
Duloxetine
venlafaxine
mirtazapine
tetracycline antidepressant
duloxetine
SNRI
venlafaxine
SNRI
What are the TCA antidepressants?
Imipramine
clomipramine
Amitriptyline
mirtazapine
imipramine
TCA antidepressant
clomipramine
TCA antidepressant
amitriptyline
TCA antidepressant
What are the MAOIs?
phenelzine
phenelzine
MAOI
what are the local anesthetics?
xylocaine
novocaine
xylocaine
local anesthetic
novocaine
local anesthetic
What are the parenteral anesthetics?
Diprivan (propofol)
Diprivan
Parenteral anesthetics
What are the rapid acting insulins?
insulin lispro
glulisine
aspart
insulin lispro
rapid acting insulin
glulisine
rapid acting insulin
What is the short acting insulin?
regular insulin
regular insulin
short acting insulin
What are the intermediate acting insulins?
NPH
What are the long actin insulins?
insulin glargine
insulin detemir
insulin glargine
long acting insulin
insulin detemir
long acting insulin
what are the biguanides?
metformin
metformin
biguanide
what are the sulfonyureas?
glipizide
glyburide
glipizide
sulfonyurea (antidiabetic medication)
glyburide
sulfonyurea (antidiabetic)
what are the glinides?
repaglinide (antidiabetic med)
repaglinide
glinide (antidiabetic med)
what are the thiazolidinediones?
(glitazones)
pioglitazone
pioglitazone
thiazolidinedione or glitizones (antidiabetic med)
what are the alpha-glucosidases?
acarbose
acarbose
alpha-glucosidase
what are the dipeptidyl peptidase IV inhibitors (gliptins)?
sitagliptin
stigaliptin
dipeptidyl peptidase IV inhibitor (gliptins)
glucagon
hyperglycemic agent
What are the hyperglycemic agents?
50% dextrose
glucagon
levothyroxine
medications for hypothyrodisim
what are the medications for hypothyroidism?
levothyroxine
what are the antithyroid medications?
PTU
methimazole
radioactive iodine
PTU
antithyroid medication, treats hyperthyroidism
methimazole
antithyroid medication, treats hyperthyroidism
radioactive iodine
antithyroid medication, treats hyperthyroidism
What are the urinary tract antiseptics?
nitrofurantoin
nalidixic acid
methenamine
nitrofurantoin
urinary tract antiseptic
nalidixic acid
urinary tract antiseptic
methenamine
urinary tract antiseptic
what are the anticholinergic incontinence drugs?
oxybutynin
darifenacin
solifenacin
tolterodine
oxybutynin
anticholinergic incontinence drug
darifenacin
anticholinergic incontinence drug
solifenacin
anticholinergic incontinence drug
tolterodine
anticholinergic incontinence drug
what is the cholinergic drugs?
bethanochol
what are the penicillins?
penicillin
penicillin G and V
ampicillin
{Zosyn, timentin, augmentin, Unasyn all have penicillin too}
zosyn
timentin
augmentin
unasyn
all are penicillins
what are the cephalosporins?
cephalexin
cephalexin
is a cephalosporin
What are the monobactams?
Aztreonam [an antibiotic]
Aztreonam
monobactam antibiotic
What are the carbapenems?
end in ——penem
imipenem and meropenem
imipenem and meropenem
carbapenem antibiotics
vancomycin
antibiotic
what are the tetracyclines?
doxycycline minocycline
doxycyclin
tetracycline antibiotic
minocycline
tetracycline antibiotic
What are the macrolides?
Erythromycin
azithromycin
clarithromycin
erythromycin
macrolide antibiotic
azithromycin
macrolide antibiotic
clarithromycin
macrolide antibiotic
what are the aminoglycosides?
gentamicin
often end in -mycin or -micin
What are the fluoroquinolones?
end in -floxacin
ciprofloxacin
levofloxacin
ciprofloxacin
fluoroquinolone antibiotic
levofloxacin
fluoroquinolone antibiotic
what are the two types of antiparastitics and what are they used for?
metronidazole -protozoan infections
chloroquine -to treat malaria
iodoquinol
tinidazole
antiparasticis
primaquine
quinine
antiparasitics, antimalarial
what are the antifungal medications?
Ketoconazole (Nizoral)
Itraconazole (Sporanox)
Miconazole (Monistat)
Clotrimazole (Lotrimin)
amphotericin B
Nystatin
Ketoconazole
antifungal medication
Itraconazol
antifungal medication
Miconazole
antifungal medication
Clotrimazole
antifungal medication
amphotericin B
antifungal medication
What are the antivirals?
acyclovir
ganciclovir
interferon alfa -2b
oseltamiver
ribavirin
Acyclovir
– treats herpes simplex and herpes zoster
Ganciclovir
– treats cytomegalovirus (CMV)
Interferon alfa
– treats hepatitis B and C
Oseltamiver
– treats influenza
Ribavirin
– treats respiratory syncytial virus (RSV)
What the antihistamines for respiratory?
First generation
Diphenhydramine (Benadryl)
Promethazine (Phenergan)
Dimenhydrinate (Dramamine)
Second Generation
Loratadine (Claritin)
Cetirizine (Zyrtec)
Fexofenadine (Allegra)
Desloratadine (Clarinex
diphenhydramine
first gen antihistamine
promethazine
first gen antihistamine
dimenhydrinate
first generation antihistamine
lortatdine
second gen antihistamine
cetirizine
second gen antihistamine
fexofenadine
second gen antihistamine
desloratadine
second generation antihistamine
what are the nasal decongestants?
phenylephrine
ephedrine
naphazoline
pseudoephedrine
phenylephrine
nasal decongestant
ephedrine
nasal decongestant
naphazoline
nasal decongestant
psudoephedrine
nasal decongestant
oxymetazoline
alpha adrenergic agonist, decongestant
anticholinergic nasal decongestants
ipatropium
ipatropium
anticholinergic nasal decongestant
corticosteroid nasal spray
fluticasone propionate nasal decongestant
fluticasone propionate nasal decongestant
corticosteroid nasal spray
what are the antitussives?
codeine
dextromethorphan
benzonatate
diphenhydramine
codeine
antitussive
dextromethorphan
antitussive
benzonatate
antitussive
diphenhydramine
antitussive
What are the expectorants?
guaifenesin
guaifenesin
expectorant
What are the mucolytics?
acetylcystine
hypertonic saline
acetylcystine
mucolytic
hypertonic saline
mucolytic
What are the beta 2 adrenergic agonist bronchodilators?
albuterol
levabuterol
formoterol
salmeterol
terbutaline
albuterol
beta 2 adrenergic agonist bronchodilators
levabuterol
beta 2 adrenergic agonist bronchodilators
formoterol
beta 2 adrenergic agonist bronchodilators
salmeterol
beta 2 adrenergic agonist bronchodilators
terbutaline
beta 2 adrenergic agonist bronchodilators
What are the anticholinergic bronchodilators?
ipatropium
tiotropium
ipatropium
anticholinergic bronchodilators
tiotropium
anticholinergic bronchodilators
What are the xanthine bronchodilators?
theophylline
methylxanthines
theophylline
xanthine bronchodilator
methylxanthines
xanthine bronchodilator
What are the non bronchodilating respiratory medication classes?
leukotriene receptor antagonists
mast cell stabilizers
corticosteroids/glucocorticosteroids
What are the bronchodilator medication classes?
beta adrenergic agonists
anticholinergics
xanthines
What are the leukotriene non bronchodilating respiratory medications?
montelukast
zafirlukast
zileuton
montelukast
leukotriene non bronchodilating respiratory medication
zafirlukast
leukotriene non bronchodilating respiratory medication
zileuton
leukotriene non bronchodilating respiratory medication
Inhaled
Beclomethasone (Beconase, Qvar)
Budesonide (Pulmacort)
Budesonide and formoterol (Symbicort)
Fluticasone (Flonase)
Fluticasone and salmeterol (Advair HFA Inhaler)
Mometasone and formoterol (Dulera)
Oral:
Prednisone (Steraped)
Prednisolone (Predicort)
IV
Hydrocortisone (Solu-Corteg)
Methylprednisolone (Solu-Medrol)
glucocorticoid nonbronchodilating respiratory medications
Cromolyn is a ?
mast cell stabilizer
what are the mast cell stabilizers?
cromolyn
What are the anticoagulants ?
heparin
low molecular weight heparins: enoxaparin, dalteparin
warfarin
What are the antiplatelets?
aspirin
ADP inhibitors: clopidogrel, ticlopidine
Glypoprotein inhibitors: eptifibatide, tirofiban
heparin
anticoagulant
enoxaparin
anticoagulant
dalteparin
anticoagulant
warfarin
anticoagulant
What re the centrally acting adrenergics for blood pressure?
clonidine
guanfacine
methyldopa
clonidine
centrally acting adrenergic for blood pressure
guanfacine
centrally acting adrenergic for blood pressure
methyldopa
centrally acting adrenergic for blood pressure
what are the cardiac glycosides?
digoxin
digoxin
cardiac glycosides
What are the different diuretic classes?
thiazide diuretics
loop diuretics
potassium sparingg diuretics
osmotic diuretics
What are the different diuretic classes?
thiazide diuretics
loop diuretics
potassium sparing diuretics
osmotic diuretics
What are the thiazide diuretics?
hydrochlorothiazide
chlorothiazide
(thiazide lke -metolazone)
hydrochlorothiazide
thiazide diuretic
chlorothiazide
thiazide diuretic
metolazone
thiazide like diuretic
What are the loop diuretics ?
ethacrynic acid
torasemide
furosemide
azosemide
bumetanide
ethacrynic acid
loop diuretics
torasemide
loop diuretics
furosemide
loop diuretics
azosemide
loop diuretics
bumetanide
loop diuretics
what are the potassium sparing diuretics ?
spironolactone
triamterene
spironolactone
potassium sparing diuretics
triamterene
potassium sparing diuretics
What are the osmotic diuretics?
mannitol
mannitol
osmotic diuretics
digoxin immune fab
antidote for digoxin toxicity, only used in severe cases
what are the nitrates/nitrites for angina?
nitroglycerin
isosorbide mononitrate
nitroglycerin
nitrates/nitrites for angina
isosorbide mononitrate
nitrates/nitrites for angina
What are the antidiarrheal medications?
bismuth subsalicylate (pepto bismol)
diphenoxylate HCL (lomotil )
Loperamide hydroxychloride (immodium)
bismuth subsalicylate
antidiarrheal medication
diphenoxylate HCL
antidiarrheal medication (aka lomotil )
loperamide hydroxychloride
antidiarrheal medication (aka immodium )
What are the different classes for laxatives?
bulk forming
hyperosmotic cathartics
stool softeners
lubricants
saline laxatives
What are the bulk forming laxatives
psyllium
bisacodyl
psyllium
bulk forming laxative
bisacodyl
bulk forming laxative
what are the hyperosmotic cathartics laxatives ?
polyethylene glycol
polyethylene glycol
hyperosmotic cathartics
What are the stool softeners?
Docusate Sodium (Colace)
Docusate Sodium and Senna
Docusate Sodium
stool softener
Docusate Sodium and Senna
stool softener
what are the lubricants?
mineral oil
mineral oil
lubricant laxatives
What are the saline laxatives?
Magnesium hydroxide (Milk of Magnesia)
Magnesium citrate (Best for Bowel Prep!)
Sodium phosphate (Fleets)
Magnesium hydroxide
saline laxative (aka milk of mag)
Magnesium citrate
saline laxative (best for bowel prep)
sodium phosphate
saline laxative (fleets enema)
What are the different classes of antiemetics?
antihistamine
serotonin receptor antagonist
anticholinergic
phenothiazine
What are the antiemetic antihistamines?
Hydroxyzine hydrochloride
Meclizine hydrochloride
Dimenhydrinate
hydroxyzine HCL
antiemetic antihistamine
meclizine HCL
antiemetic antihistamine
dimenhydrinate
antiemetic antihistamine
What are the serotonin recptor antagonist antiemetics?
ondansetron HCL
metoclopramide
ondansetron HCL
serotonin receptor antagonist antiemetics
metoclopramide
serotonin receptor antagonist antiemetics
What are the anticholinergic antiemetics?
scopalamine
scopalamine
anticholinergic antiemetics
What are the phenothiazine antiemetics?
Prochlorperazine
Promethazine hydrochloride
Prochlorperazine
phenothiazine antiemetics
Promethazine hydrochloride
phenothiazine antiemetics
metolazone
thiazide like diuretic