diabetic drugs Flashcards
short acting
Regular insulin (Humulin R/Novolin R)
- SQ
- Seen given IV
- 0.5 to 1 hr
Regular insulin (Humulin R/Novolin R)
rapid acting insulin
- Lisproe
- Aspart
Intermediate acting insulin
Insulin isophane suspension (NPH)
- Action time – 15 minutes
- Take with or right before meal to prevent hypoglycemia
- SQ
rapid acting insulin
- Cloudy insulin
- Mixed with regular
Intermediate acting insulin
What two insulins are often mixed together?
RN – Regular first then NPH
short and intermediate
what is short and rapid acting based on?
Short acting or rapid acting given based on FSBS
what is Biguanides?
an oral diabetic drug class used in 2 and the drug is metformin
- Decreases glucose production in the liver/intestinal absorption of glucose
- Improves insulin receptor sensitivity
- A.E. GI and metallic taste
- Long term effects: b12 and b9 deficiency
- DON’T USE: Iodine containing contrast, if pt is predisposed hypoxia or lactic acidosis
metformin
drugs in Sulfonylureas class?
Glipizide
Glyburide
- Bind to receptor sites in pancreas to stimulate the release of insulin
- decrease glucagon
- best in early diabetes 2
- STOP if/when insulin is needed
- only pts with working beta cells in the pancreas- not for type 1 diabetics
- NO: NPO, alcohol, elderly, allergy to sulfonamide, hypoglycemia pts
- A.E. hypoglycemia, weight gain, GI and rash
Sulfonylureas
what drugs are too similar to be used together?
Sulfonylureas and Glinides (Meglitinides)
what are the drugs in the drug class Glinides (Meglitinides)?
Repaglinide
- Shorter duration than sulfonylureas
- Given with each meal
- A.E. hypoglycemia, weight gain
Glinides (Meglitinides); Repaglinide