drugs used in rheum

Question 1

Describe penacillamine and its uses

Answer 1

RA - DMARD
Cleat cysteine in Wilsons

Question 2

Outline the treatment for GOUT

Answer 2

Allopurinol - inhibits xanthine oxidase (prevention).
Give after 1st attack. 2/52 post recovery.

Colchicine - inhibits macrophage migraition into joint (loose stool)

NSAIDS - acute, stop at 2/7 relief (PPI)

Question 3

Name drugs which may cause bronchospasm:

Answer 3

Aspirin
NSAIDS
Adenosine
Atenolol (cardio bblocker)
NAC

Question 4

Common drugs leading to movement disorders

Answer 4

PD meds
Haloperidol
SSRIs

Question 5

Drugs commonly causing Gynaecomastia

Answer 5

digoxin
spironolatone
cimetidine

Question 6

Drugs which may cause hypothyroidism

Answer 6

amiodarone
carbimazole
lithium
propythiouracil

Question 7

Drugs potentially causing hepatitis

Answer 7

amiodarone
statins
isoniazid
paracetamol
valproate

Question 8

drugs causing cholestasis:

Answer 8

carbemazepine
co-amoxiclav
erythromycin
nitrofurantoin
sulphonylureas
coc

Question 9

Drug induced lung fibrosis:

Answer 9

amiodarone
cytotoxics
methotrexate
nitrofurantoin

Question 10

drug induces SIADH:

Answer 10

opiates
carbemazepine

Question 11

drugs causing acute pancreatitis:

Answer 11

steriods
statins
thiazides
azathioprine