drugs used in diabetes Flashcards
What is the uses of insulin?
Type I DM.
Type II when need for glycemic control (hospitalized, stress, sepsis, ICU admission).
Adjuvant to other diabetes drug to control blood sugar (type II).
Hyperkalemia.
DKA.
Types of Insulin
Ultra-short (Rapid)
Short
Intermediate
Long
What is the groups of Insulin secretagogues?
Sulfonylureas
Meglitinides
Which the following is Meglitinides?
Repaglinide, Nateglinide
What is the Sulfonylureas?
First generation
Tolbutamide,Chlorpropamide
Second generation
Glipizide ,Glibenclamide
What’s the groups of Insulin sensitizers?
Biguanides
Thiazolidinediones (Glitazone)
What’s Biguanides?
Metformin
What’s the side effects of Metformin?
• GIT disturbances:
Should be taken with meals and started at a low dose to
• Lactic acidosis (rare but Serious)
• Interference with vit. B12 absorption
What’s the Glitazone?
Pioglitazone,
Rosiglitazone
What’s the GLP-1 agonists ?
Dulaglutide,
Exenatide
What’s the following Dipeptidyl peptidase-4 (DPP- 4 ) inhibitors?
Sitagliptin,
Vildagliptin
What’s the 𝜶-GLUCOSIDASE INHIBITORS ?
Acarbose
What’s the SGLT2)
INHIBITORS?
Canagliflozin,
Dapagliflozin,