corticosteriods Flashcards
What the effect of Glucocorticoids?
Metabolic effects:
stimulate gluconeogenesis
fat deposition in certain areas (e.g., the face (moon facies), shoulder and back (buffalo hump)
muscle protein catabolism
Catabolic effects on bone lead to osteoporosis
Immunosuppressive effects
Anti-inflammatory effect
stimulate gastric acid secretion
The ueses of Glucocorticoids?
Adrenal disorders:
Non-adrenal disorders
Glucocorticoids (SHORT ACTING)
cortisone hydrocortisone
INTERMEDIATE ACTING?
Methylprednisolone prednisolone
prednisone
LONG ACTING?
Betamethasone
dexamethason
What’s the Mineralocorticoids?
Aldosterone
Fludrocortisone
Corticosteroid Antagonists?
Spironolactone &Eplerenone
Mifepristone
What’s the Synthesis Inhibitors?
Ketoconazole