drugs used in adjunct therapy

Question 1

what are the 4 drugs we have to know for adjunct therapy

Answer 1

1.antianxiety and muscle relaxants

2. anticonvulsant
3. antidepressant
4. others

Question 2

What are some example of anti depressan

Answer 2

tricyclic antidepressant like amitriptyline

Question 3

How does amitriptyline work

Answer 3

increases serotonin and norepinephrine by blocking transporters at pre synaptic membrane, so NA and 5HT cannot be returned back to the pre synaptic membrane

Question 4

what does anti depressant aim to achiev

Answer 4

enhance pain relief of chronic pain

Question 5

What are some adverse effect of anti depressants

Answer 5

CVS: tachycardia, postural hypotension, cardiac arrythmia

Sedation

Anti-cholinergic effect : dry mouth, blurred vision, retention of urine, constipation