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Pharm Summer 2020 > Drugs to Know > Flashcards

Drugs to Know Flashcards

1
Q

Acetylcholine

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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2
Q

Bethanechol

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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3
Q

Carbachol

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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4
Q

Cevilmeline

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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5
Q

Nicotine

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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6
Q

Pilocarpine

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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7
Q

Verenicline

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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8
Q

Endrophoneium

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Short acting

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9
Q

Doneprezil

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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10
Q

Galantamine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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11
Q

neostigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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12
Q

Physostigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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13
Q

Pryidostigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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14
Q

Rivastigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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15
Q

Echothiophate

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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16
Q

Malathion

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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17
Q

Parathion

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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18
Q

Sarin

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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19
Q

Pralidoxime

A

Acetylcholinesterase reactivator

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20
Q

Atropine

A

Cholinergic/Ach Antagonists/blocker

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21
Q

Cyclopentolate

A

Cholinergic/Ach Antagonis/blocker

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22
Q

Dicyclomine

A

Cholinergic/ACh

Antagonist/blocker

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23
Q

Ipratropium

A

Cholinergic/Ach Antagonist/blocker

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24
Q

Homatropine

A

Cholinergic/Ach Antagonist/blocker

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25
Q

Oxybutynin

A

Cholinergic/Ach Antagonist/blocker

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26
Q

Scopolamine

A

Cholinergic/Ach Antagonist/blocker

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27
Q

Tiotropium

A

Cholinergic/Ach Antagonist/blocker

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28
Q

Tropicamide

A

Cholinergic/Ach Antagonist/blocker

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29
Q

Epinephrine

A

Non-selective alpha and beta antagonist

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30
Q

Midodrine

A

Alpha 1 agonist

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31
Q

Phenylephrine

A

Alpha 1 agonist

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32
Q

Tetrahydrozoline (visine)

A

Alpha 1 agonist

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33
Q

Apraclonidine (iodine)

A

Alpha 2 agonist

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34
Q

Brimonidine (alphagan-P)

A

Alpha 2 agonist

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35
Q

Conidine

A

Alpha 2 agonist

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36
Q

Isoproterenol

A

Non selective beta agonist

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37
Q

Dobutamine

A

Beta 1 agonist

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38
Q

Albuterol

A

Beta 2 agonist

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39
Q

Formoterol

A

Beta 2 agonist

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40
Q

Metaproterenol

A

Beta 2 agonist

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41
Q

Salmeterol

A

Beta 2 agonist

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42
Q

Terbutaline

A

Beta 2 agonist

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43
Q

Phenoxybenzamine

A

Non-selective alpha antagonist

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44
Q

Alfuzosin

A

Alpha 1 antagonist

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45
Q

Doxazosin

A

Alpha 1 antagonist

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46
Q

Prazosin

A

Alpha 1 antagonist

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47
Q

Tamsulosin (Flomax)

A

Alpha 1 antagonist

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48
Q

Terazosin

A

Alpha 1 antagonist

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49
Q

Yohimbine

A

Alpha 2 antagonist

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50
Q

Carteolol

A

Non-selective beta antagonist

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51
Q

Carvedilol

A

Non-selective beta antagonist

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52
Q

Labetalol

A

Non-selective beta antagonist

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53
Q

Nadolol

A

Non-selective beta antagonist

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54
Q

Pindolol

A

Non-selective beta antagonist

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55
Q

Propranolol

A

Non-selective beta antagonist

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56
Q

Timolol (timoptic)

A

Non-selective beta antagonist

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57
Q

Acebutolol

A

Beta- 1 selective antagonist

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58
Q

Atenolol

A

Beta- 1 selective antagonist

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59
Q

Betaxolol

A

Beta- 1 selective antagonist

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60
Q

Bisoprolol

A

Beta- 1 selective antagonist

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61
Q

Esmolol

A

Beta- 1 selective antagonist

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62
Q

Metoprolol

A

Beta- 1 selective antagonist

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63
Q

Nebivolol

A

Beta- 1 selective antagonist

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64
Q

Penicillin G

A

Penicillin
1st gen- natural
injection only

Cell wall inhibitor by transpeptidase

*Susceptible to inactivation by B-lactamases

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65
Q

Penicillin V

A

Penicillin
1st gen- natural
Oral only

Cell wall inhibitor by transpeptidase

*Susceptible to inactivation by B-lactamases

66
Q

Dicloxacillin

A

Penicillin
2nd gen- Penicillinase (B lactamase) resistant
Cell wall inhibitor by transpeptidase

67
Q

Methicillin

A

Penicillin
2nd gen- Penicillinase (B lactamase) resistant
Don’t use. Only for MRSA testing
Cell wall inhibitor by transpeptidase

68
Q

Nafcillin

A

Penicillin
2nd gen- Penicillinase (B lactamase) resistant
Cell wall inhibitor by transpeptidase

69
Q

Oxacilin

A

Penicillin
2nd gen- Penicillinase (B lactamase) resistant
Cell wall inhibitor by transpeptidase

70
Q

Amoxicillin

A

Penicillin
3rd Gen- ampinopenicillins. Gram postive and easy gram negative
Cell wall inhibitor by transpeptidase

71
Q

Ampicillin

A

Penicillin
3rd Gen- aminopenicillins. Gram postive and easy gram negative
Cell wall inhibitor by transpeptidase

72
Q

Piperacillin

A

Penicillin
4th gen- extended spectrum.
Good gram negative coverage
Cell wall inhibitor by transpeptidase

73
Q

Ticarcillin

A

Penicillin
4th gen- extended spectrum.
Good gram negative coverage
Cell wall inhibitor by transpeptidase

74
Q

Cefadroxil

A

Cephalosporins
1st gen
Gram positive coverage for skin infections
Cell wall inhibitor by transpeptidase

75
Q

Cefazolin

A

Cephalosporins
1st gen
Gram positive coverage for skin infections
Cell wall inhibitor by transpeptidase

76
Q

Cephalexin (Keflex)

A

Cephalosporins
1st gen
Gram positive coverage for skin infections
Cell wall inhibitor by transpeptidase

77
Q

Cefaclor

A 
Cephalosporins
2nd gen 
Some gram positive with improved gram negative 
Intra abdominal infection 
Cell wall inhibitor by transpeptidase
78
Q

Cefotetan

A 
Cephalosporins
2nd gen 
Some gram positive with improved gram negative 
Intra abdominal infection 
Cell wall inhibitor by transpeptidase
79
Q

Cefoxitin

A 
Cephalosporins
2nd gen 
Some gram positive with improved gram negative 
Intra abdominal infection 
Cell wall inhibitor by transpeptidase
80
Q

Cefprozil

A 
Cephalosporins
2nd gen 
Some gram positive with improved gram negative 
Intra abdominal infection 
Cell wall inhibitor by transpeptidase
81
Q

Cefuroxime

A 
Cephalosporins
2nd gen 
Some gram positive with improved gram negative 
Intra abdominal infection 
Cell wall inhibitor by transpeptidase
82
Q

Cefdinir

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

83
Q

Cefditoren

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

84
Q

Cefixime

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

85
Q

Cefotaxime

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

86
Q

Cefpodoxime

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

87
Q

Ceftazidime

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

88
Q

Ceftibuten

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

89
Q

Ceftriaxone

A

Cephalosporins
3rd Gen
Gram (-)
Cell wall inhibitor by transpeptidase

90
Q

Cefepime

A

Cephalosporins
4th Gen
Used for serious infections- Broad spectrum gram positive and negative and pseudomonas
Cell wall inhibitor by transpeptidase

91
Q

Ceftaroline

A

Cephalosporins
5th gen
Cell wall inhibitor by transpeptidase

92
Q

Ceftozolane (combined with Tazobactam)

A

Cephalosporins
5th gen
Cell wall inhibitor by transpeptidase

93
Q

Clavulanic acid + amoxicillin

A

B lactamase inhibitor + antibiotic combo

Cell wall inhibotor

94
Q

Clavulanic acid + ticarcillin

A

B lactamase inhibitor + antibiotic combo

Cell wall inhibotor

95
Q

Sulbactam + ampicillin

A

B lactamase inhibitor + antibiotic combo

Cell wall inhibotor

96
Q

Trazobactam + piperacillin

A

B lactamase inhibitor + antibiotic combo

Cell wall inhibotor

97
Q

Bacitracin

A

Peptidoglycan Cell wall inhibotor

98
Q

Daptomycin

A

Cell wall inhibotor

99
Q

Telavancin

A

Cell wall inhibotor

100
Q

Vancomycin

A

Peptidoglycan Cell wall inhibotor

101
Q

Demeclocycline

A

Tetracycline

Protein synthesis inhibitor by 30S subunit

102
Q

Doxycycline

A

Tetracycline

Protein synthesis inhibitor by 30S subunit

103
Q

Minocycline

A

Tetracycline

Protein synthesis inhibitor by 30S subunit

104
Q

Tetracycline

A

Tetracycline

Protein synthesis inhibitor by 30S subunit

105
Q

Amikacin

A

Aminoglycosides

Protein synthesis inhibitor by 30S subunit

106
Q

Gentamicin

A

Aminoglycosides

Protein synthesis inhibitor by 30S subunit

107
Q

Neomycin

A

Aminoglycosides

Protein synthesis inhibitor by 30S subunit

108
Q

Streptomycin

A

Aminoglycosides

Protein synthesis inhibitor by 30S subunit

109
Q

Tobramycin

A

Aminoglycosides

Protein synthesis inhibitor by 30S subunit

110
Q

Azithromycin (zithromax, z pack)

A

Macrolides

Protein synthesis inhibitor by 50S subunit

111
Q

Clarithromycin

A

Macrolides

Protein synthesis inhibitor by 50S subunit

112
Q

Erythromycin

A

Macrolides

Protein synthesis inhibitor by 50S subunit

113
Q

Fidaxomicin

A

Macrolides

Protein synthesis inhibitor by 50S subunit

114
Q

Clindamycin

A

Protein synthesis inhibitor by 50S subunit

115
Q

Linezolid

A

Protein synthesis inhibitor by 50S subunit

116
Q

Ethambutol

A

First line antimycobacterial drug (tuberculosis)
Interferes will cell wall synthesis
Optic Neuritis

117
Q

Isoniazid

A

First line antimycobacterial drug (tuberculosis)

Interferes will cell wall synthesis

118
Q

Pyrazinimide

A

First line antimycobacterial drug (tuberculosis)

pH change inhibits cell growth

119
Q

Rifampin

A

First line antimycobacterial drug (tuberculosis)

Blocks transcription

120
Q

Rifabutin

A

First line antimycobacterial drug (tuberculosis)

Blocks transcription

121
Q

Rifapentine

A

First line antimycobacterial drug (tuberculosis)

Blocks transcription

122
Q

Clotrimazole

A

Anti-fungal
Azole
Inhibits ergosterol formation: disrupts membrane structure and function

123
Q

Fluconazole

A

Anti-fungal
Azole
Inhibits ergosterol formation: disrupts membrane structure and function

124
Q

Itraconazole

A

Anti-fungal
Azole
Inhibits ergosterol formation: disrupts membrane structure and function

125
Q

Ketoconazole

A

Anti-fungal
Azole
Inhibits ergosterol formation: disrupts membrane structure and function

126
Q

Miconazole

A

Anti-fungal
Azole
Inhibits ergosterol formation: disrupts membrane structure and function

127
Q

posaconazole

A

Anti-fungal
Azole
Inhibits ergosterol formation: disrupts membrane structure and function

128
Q

voriconazole

A

Anti-fungal
Azole
Inhibits ergosterol formation: disrupts membrane structure and function

129
Q

Anidulalfungin

A

Anti-fungal
Echinocandin
Disrupts fungal cell wall

130
Q

Capsofungin

A

Anti-fungal
Echinocandin
Disrupts fungal cell wall

131
Q

Micafungin

A

Anti-fungal
Echinocandin
Disrupts fungal cell wall

132
Q

Amphotercerin B

A

Anti-fungal
Polyene Macrolide
Bind ergosterol and create pore
Don’t take with azole

133
Q

Natamycin

A

Anti-fungal
Polyene Macrolide
Bind ergosterol and create pore
Don’t take with azole

134
Q

Nystatin

A

Anti-fungal
Polyene Macrolide
Bind ergosterol and create pore
Don’t take with azole

135
Q

Naftifine

A

Anti-fungal
Allylamines
Dual function: Inhibits enzyme squalene epoxidase. Blocks biosynthesis of ergosterol and squalene levels build up and become toxic.

136
Q

Terbanifine

A

Anti-fungal
Allylamines
Dual function: Inhibits enzyme squalene epoxidase. Blocks biosynthesis of ergosterol and squalene levels build up and become toxic.

137
Q

Tolnaftate

A

Anti-fungal
Allylamines
Dual function: Inhibits enzyme squalene epoxidase. Blocks biosynthesis of ergosterol and squalene levels build up and become toxic.

138
Q

Flucytosine

A

Anti-fungal
“other”
Enters fungal cell and disrupts DNA/protein synthesis

139
Q

Oseltamivir

A

Anti-viral
Influenza A and B
Inhibit viral neurominidase

140
Q

Zanamivir

A

Anti-viral
Influenza A and B
Inhibit viral neurominidase

141
Q

Rimantidine

A

Anti-viral
Influenza A
Inhibitors of viral coating- virus cannot be internalized by host

142
Q

Amantidine

A

Anti-viral
Influenza A
Inhibitors of viral coating- virus cannot be internalized by host

143
Q

Acyclovir

A

Anti-herpes

Inhibit Viral DNA replication

144
Q

Famcyclovir

A

Anti-herpes

Inhibit Viral DNA replication

145
Q

Valacyclovir

A

Anti-herpes

Inhibit Viral DNA replication

146
Q

Galcyclovir

A

Anti-herpes

Inhibit Viral DNA replication

147
Q

Trifluridine

A

Anti-herpes

Inhibit Viral DNA replication

148
Q

Cidofovir

A

Anti-herpes

Inhibit Viral DNA replication

149
Q

Interferon A

A

Hepatitis B/C treatment

MOA not understood. Maybe inhibits RNA translation.

150
Q

Daclatasvir

A

Hepatitis B/C treatment
5A inhibitor
Interfere with viral RNA replication

151
Q

Elbasvir

A

Hepatitis B/C treatment
5A inhibitor
Interfere with viral RNA replication

152
Q

Ledipasvir

A

Hepatitis B/C treatment
5A inhibitor
Interfere with viral RNA replication

153
Q

Ombitasvir

A

Hepatitis B/C treatment
5A inhibitor
Interfere with viral RNA replication

154
Q

Grazoprevir

A

Hepatitis B/C treatment
Protease Inhibitor
Prevent viral maturation of new particles

155
Q

Paritaprevir

A

Hepatitis B/C treatment
Protease Inhibitor
Prevent viral maturation of new particles

156
Q

Simeprevir

A

Hepatitis B/C treatment
Protease Inhibitor
Prevent viral maturation of new particles

157
Q

Adefovir

A

Hepatitis B/C treatment
Nucleotide/nucleoside inhibitor
Insert into RNA chain and causes termination

158
Q

Entecavir

A

Hepatitis B/C treatment
Nucleotide/nucleoside inhibitor
Insert into RNA chain and causes termination

159
Q

Lamivaudine

A

Hepatitis B/C treatment
Nucleotide/nucleoside inhibitor
Insert into RNA chain and causes termination

160
Q

Sofosbuvir

A

Hepatitis B/C treatment
Nucleotide/nucleoside inhibitor
Insert into RNA chain and causes termination

161
Q

Tenofovir

A

Hepatitis B/C treatment
Nucleotide/nucleoside inhibitor
Insert into RNA chain and causes termination

Pharm Summer 2020 (18 decks)

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