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Pharm Summer 2020 > Drugs to Know > Flashcards

Drugs to Know Flashcards

1
Q

Acetylcholine

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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2
Q

Bethanechol

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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3
Q

Carbachol

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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4
Q

Cevilmeline

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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5
Q

Nicotine

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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6
Q

Pilocarpine

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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7
Q

Verenicline

A

Direct Cholinomimetic Drug

Ach/cholinergic agonist

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8
Q

Endrophoneium

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Short acting

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9
Q

Doneprezil

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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10
Q

Galantamine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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11
Q

neostigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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12
Q

Physostigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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13
Q

Pryidostigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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14
Q

Rivastigmine

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
Intermediate acting

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15
Q

Echothiophate

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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16
Q

Malathion

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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17
Q

Parathion

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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18
Q

Sarin

A

Indirect Cholinomimetic Drug
Ach/Cholinergic agonist
long acting

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19
Q

Pralidoxime

A

Acetylcholinesterase reactivator

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20
Q

Atropine

A

Cholinergic/Ach Antagonists/blocker

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21
Q

Cyclopentolate

A

Cholinergic/Ach Antagonis/blocker

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22
Q

Dicyclomine

A

Cholinergic/ACh

Antagonist/blocker

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23
Q

Ipratropium

A

Cholinergic/Ach Antagonist/blocker

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24
Q

Homatropine

A

Cholinergic/Ach Antagonist/blocker

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25
Oxybutynin
Cholinergic/Ach Antagonist/blocker
26
Scopolamine
Cholinergic/Ach Antagonist/blocker
27
Tiotropium
Cholinergic/Ach Antagonist/blocker
28
Tropicamide
Cholinergic/Ach Antagonist/blocker
29
Epinephrine
Non-selective alpha and beta antagonist
30
Midodrine
Alpha 1 agonist
31
Phenylephrine
Alpha 1 agonist
32
Tetrahydrozoline (visine)
Alpha 1 agonist
33
Apraclonidine (iodine)
Alpha 2 agonist
34
Brimonidine (alphagan-P)
Alpha 2 agonist
35
Conidine
Alpha 2 agonist
36
Isoproterenol
Non selective beta agonist
37
Dobutamine
Beta 1 agonist
38
Albuterol
Beta 2 agonist
39
Formoterol
Beta 2 agonist
40
Metaproterenol
Beta 2 agonist
41
Salmeterol
Beta 2 agonist
42
Terbutaline
Beta 2 agonist
43
Phenoxybenzamine
Non-selective alpha antagonist
44
Alfuzosin
Alpha 1 antagonist
45
Doxazosin
Alpha 1 antagonist
46
Prazosin
Alpha 1 antagonist
47
Tamsulosin (Flomax)
Alpha 1 antagonist
48
Terazosin
Alpha 1 antagonist
49
Yohimbine
Alpha 2 antagonist
50
Carteolol
Non-selective beta antagonist
51
Carvedilol
Non-selective beta antagonist
52
Labetalol
Non-selective beta antagonist
53
Nadolol
Non-selective beta antagonist
54
Pindolol
Non-selective beta antagonist
55
Propranolol
Non-selective beta antagonist
56
Timolol (timoptic)
Non-selective beta antagonist
57
Acebutolol
Beta- 1 selective antagonist
58
Atenolol
Beta- 1 selective antagonist
59
Betaxolol
Beta- 1 selective antagonist
60
Bisoprolol
Beta- 1 selective antagonist
61
Esmolol
Beta- 1 selective antagonist
62
Metoprolol
Beta- 1 selective antagonist
63
Nebivolol
Beta- 1 selective antagonist
64
Penicillin G
Penicillin 1st gen- natural injection only Cell wall inhibitor by transpeptidase *Susceptible to inactivation by B-lactamases
65
Penicillin V
Penicillin 1st gen- natural Oral only Cell wall inhibitor by transpeptidase *Susceptible to inactivation by B-lactamases
66
Dicloxacillin
Penicillin 2nd gen- Penicillinase (B lactamase) resistant Cell wall inhibitor by transpeptidase
67
Methicillin
Penicillin 2nd gen- Penicillinase (B lactamase) resistant Don't use. Only for MRSA testing Cell wall inhibitor by transpeptidase
68
Nafcillin
Penicillin 2nd gen- Penicillinase (B lactamase) resistant Cell wall inhibitor by transpeptidase
69
Oxacilin
Penicillin 2nd gen- Penicillinase (B lactamase) resistant Cell wall inhibitor by transpeptidase
70
Amoxicillin
Penicillin 3rd Gen- ampinopenicillins. Gram postive and easy gram negative Cell wall inhibitor by transpeptidase
71
Ampicillin
Penicillin 3rd Gen- aminopenicillins. Gram postive and easy gram negative Cell wall inhibitor by transpeptidase
72
Piperacillin
Penicillin 4th gen- extended spectrum. Good gram negative coverage Cell wall inhibitor by transpeptidase
73
Ticarcillin
Penicillin 4th gen- extended spectrum. Good gram negative coverage Cell wall inhibitor by transpeptidase
74
Cefadroxil
Cephalosporins 1st gen Gram positive coverage for skin infections Cell wall inhibitor by transpeptidase
75
Cefazolin
Cephalosporins 1st gen Gram positive coverage for skin infections Cell wall inhibitor by transpeptidase
76
Cephalexin (Keflex)
Cephalosporins 1st gen Gram positive coverage for skin infections Cell wall inhibitor by transpeptidase
77
Cefaclor
``` Cephalosporins 2nd gen Some gram positive with improved gram negative Intra abdominal infection Cell wall inhibitor by transpeptidase ```
78
Cefotetan
``` Cephalosporins 2nd gen Some gram positive with improved gram negative Intra abdominal infection Cell wall inhibitor by transpeptidase ```
79
Cefoxitin
``` Cephalosporins 2nd gen Some gram positive with improved gram negative Intra abdominal infection Cell wall inhibitor by transpeptidase ```
80
Cefprozil
``` Cephalosporins 2nd gen Some gram positive with improved gram negative Intra abdominal infection Cell wall inhibitor by transpeptidase ```
81
Cefuroxime
``` Cephalosporins 2nd gen Some gram positive with improved gram negative Intra abdominal infection Cell wall inhibitor by transpeptidase ```
82
Cefdinir
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
83
Cefditoren
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
84
Cefixime
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
85
Cefotaxime
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
86
Cefpodoxime
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
87
Ceftazidime
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
88
Ceftibuten
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
89
Ceftriaxone
Cephalosporins 3rd Gen Gram (-) Cell wall inhibitor by transpeptidase
90
Cefepime
Cephalosporins 4th Gen Used for serious infections- Broad spectrum gram positive and negative and pseudomonas Cell wall inhibitor by transpeptidase
91
Ceftaroline
Cephalosporins 5th gen Cell wall inhibitor by transpeptidase
92
Ceftozolane (combined with Tazobactam)
Cephalosporins 5th gen Cell wall inhibitor by transpeptidase
93
Clavulanic acid + amoxicillin
B lactamase inhibitor + antibiotic combo | Cell wall inhibotor
94
Clavulanic acid + ticarcillin
B lactamase inhibitor + antibiotic combo | Cell wall inhibotor
95
Sulbactam + ampicillin
B lactamase inhibitor + antibiotic combo | Cell wall inhibotor
96
Trazobactam + piperacillin
B lactamase inhibitor + antibiotic combo | Cell wall inhibotor
97
Bacitracin
Peptidoglycan Cell wall inhibotor
98
Daptomycin
Cell wall inhibotor
99
Telavancin
Cell wall inhibotor
100
Vancomycin
Peptidoglycan Cell wall inhibotor
101
Demeclocycline
Tetracycline | Protein synthesis inhibitor by 30S subunit
102
Doxycycline
Tetracycline | Protein synthesis inhibitor by 30S subunit
103
Minocycline
Tetracycline | Protein synthesis inhibitor by 30S subunit
104
Tetracycline
Tetracycline | Protein synthesis inhibitor by 30S subunit
105
Amikacin
Aminoglycosides | Protein synthesis inhibitor by 30S subunit
106
Gentamicin
Aminoglycosides | Protein synthesis inhibitor by 30S subunit
107
Neomycin
Aminoglycosides | Protein synthesis inhibitor by 30S subunit
108
Streptomycin
Aminoglycosides | Protein synthesis inhibitor by 30S subunit
109
Tobramycin
Aminoglycosides | Protein synthesis inhibitor by 30S subunit
110
Azithromycin (zithromax, z pack)
Macrolides | Protein synthesis inhibitor by 50S subunit
111
Clarithromycin
Macrolides | Protein synthesis inhibitor by 50S subunit
112
Erythromycin
Macrolides | Protein synthesis inhibitor by 50S subunit
113
Fidaxomicin
Macrolides | Protein synthesis inhibitor by 50S subunit
114
Clindamycin
Protein synthesis inhibitor by 50S subunit
115
Linezolid
Protein synthesis inhibitor by 50S subunit
116
Ethambutol
First line antimycobacterial drug (tuberculosis) Interferes will cell wall synthesis Optic Neuritis
117
Isoniazid
First line antimycobacterial drug (tuberculosis) | Interferes will cell wall synthesis
118
Pyrazinimide
First line antimycobacterial drug (tuberculosis) | pH change inhibits cell growth
119
Rifampin
First line antimycobacterial drug (tuberculosis) | Blocks transcription
120
Rifabutin
First line antimycobacterial drug (tuberculosis) | Blocks transcription
121
Rifapentine
First line antimycobacterial drug (tuberculosis) | Blocks transcription
122
Clotrimazole
Anti-fungal Azole Inhibits ergosterol formation: disrupts membrane structure and function
123
Fluconazole
Anti-fungal Azole Inhibits ergosterol formation: disrupts membrane structure and function
124
Itraconazole
Anti-fungal Azole Inhibits ergosterol formation: disrupts membrane structure and function
125
Ketoconazole
Anti-fungal Azole Inhibits ergosterol formation: disrupts membrane structure and function
126
Miconazole
Anti-fungal Azole Inhibits ergosterol formation: disrupts membrane structure and function
127
posaconazole
Anti-fungal Azole Inhibits ergosterol formation: disrupts membrane structure and function
128
voriconazole
Anti-fungal Azole Inhibits ergosterol formation: disrupts membrane structure and function
129
Anidulalfungin
Anti-fungal Echinocandin Disrupts fungal cell wall
130
Capsofungin
Anti-fungal Echinocandin Disrupts fungal cell wall
131
Micafungin
Anti-fungal Echinocandin Disrupts fungal cell wall
132
Amphotercerin B
Anti-fungal Polyene Macrolide Bind ergosterol and create pore Don't take with azole
133
Natamycin
Anti-fungal Polyene Macrolide Bind ergosterol and create pore Don't take with azole
134
Nystatin
Anti-fungal Polyene Macrolide Bind ergosterol and create pore Don't take with azole
135
Naftifine
Anti-fungal Allylamines Dual function: Inhibits enzyme squalene epoxidase. Blocks biosynthesis of ergosterol and squalene levels build up and become toxic.
136
Terbanifine
Anti-fungal Allylamines Dual function: Inhibits enzyme squalene epoxidase. Blocks biosynthesis of ergosterol and squalene levels build up and become toxic.
137
Tolnaftate
Anti-fungal Allylamines Dual function: Inhibits enzyme squalene epoxidase. Blocks biosynthesis of ergosterol and squalene levels build up and become toxic.
138
Flucytosine
Anti-fungal "other" Enters fungal cell and disrupts DNA/protein synthesis
139
Oseltamivir
Anti-viral Influenza A and B Inhibit viral neurominidase
140
Zanamivir
Anti-viral Influenza A and B Inhibit viral neurominidase
141
Rimantidine
Anti-viral Influenza A Inhibitors of viral coating- virus cannot be internalized by host
142
Amantidine
Anti-viral Influenza A Inhibitors of viral coating- virus cannot be internalized by host
143
Acyclovir
Anti-herpes | Inhibit Viral DNA replication
144
Famcyclovir
Anti-herpes | Inhibit Viral DNA replication
145
Valacyclovir
Anti-herpes | Inhibit Viral DNA replication
146
Galcyclovir
Anti-herpes | Inhibit Viral DNA replication
147
Trifluridine
Anti-herpes | Inhibit Viral DNA replication
148
Cidofovir
Anti-herpes | Inhibit Viral DNA replication
149
Interferon A
Hepatitis B/C treatment | MOA not understood. Maybe inhibits RNA translation.
150
Daclatasvir
Hepatitis B/C treatment 5A inhibitor Interfere with viral RNA replication
151
Elbasvir
Hepatitis B/C treatment 5A inhibitor Interfere with viral RNA replication
152
Ledipasvir
Hepatitis B/C treatment 5A inhibitor Interfere with viral RNA replication
153
Ombitasvir
Hepatitis B/C treatment 5A inhibitor Interfere with viral RNA replication
154
Grazoprevir
Hepatitis B/C treatment Protease Inhibitor Prevent viral maturation of new particles
155
Paritaprevir
Hepatitis B/C treatment Protease Inhibitor Prevent viral maturation of new particles
156
Simeprevir
Hepatitis B/C treatment Protease Inhibitor Prevent viral maturation of new particles
157
Adefovir
Hepatitis B/C treatment Nucleotide/nucleoside inhibitor Insert into RNA chain and causes termination
158
Entecavir
Hepatitis B/C treatment Nucleotide/nucleoside inhibitor Insert into RNA chain and causes termination
159
Lamivaudine
Hepatitis B/C treatment Nucleotide/nucleoside inhibitor Insert into RNA chain and causes termination
160
Sofosbuvir
Hepatitis B/C treatment Nucleotide/nucleoside inhibitor Insert into RNA chain and causes termination
161
Tenofovir
Hepatitis B/C treatment Nucleotide/nucleoside inhibitor Insert into RNA chain and causes termination

Pharm Summer 2020 (18 decks)

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