Drugs Test 3 Flashcards
Unfractionated Heparin
Anti-Coag
Complexes with antithrombin 3, increasing activity many fold, which prevents thrombosis
Enoxaprin
Anti-Coag
Complexes with antithrombin 3, increasing activity many fold, which prevents thrombosis
Clopidogrel
Anti-Platelets
P2Y12, responsible for activation of platelets, receptor antagonist
Epitifibate
Anti-Platelets
Glycoprotein IIb/IIIa, causes platelet activation and aggregation, antagonist
Acetylsalicylic acid
Anti Platelets
COX,enzyme required for prostoglandin and thromboxane synthesis, inhibitor
Alteplase
Thrombolytics
Converts plasminogen to plasmin, causing breakdown of clots
Streptokinase
Thrombolytics
Cleaves plasminogen to plasmin, causing breakdown of clots
Metoprolol
Beta Blocker
B1 adrenergic receptor antagonist, lowering contractility and Heart Rate
Carvedilol
Beta Blocker
A1 and B adrenergic receptor antagonist, lowering contractility and Heart Rate
Diltiazem
Cardio Calcium Channel Blocker
Selective do to opening and closing of channel, active site in channel
Amlodipine
Vascular Calcium Channel Blocker
Slower opening and closing of channel
Nitroglycerin
Vasodilator
NO donor
Ranolazine
Sodium Current Inhibitor
Reduces INa activity, decreasing Ca levels, which decreases diastolic wall tension and myocardial oxygen consumption
Ivabradine
Funny Channel Inhibitor
Inhibits funny channel pacemaker current, slwoing heart rate