drugs - test 1 Flashcards

1
Q

what are the 6 SERM drugs?

A
ethynil estradiol
clomiphene
ospemifine
tamoxifen
raloxifene
fulvestrant
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2
Q

ethynil estradiol MOA

A

estrogen receptor agonist

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3
Q

clomiphene MOA

A

partial estrogen receptor agonist/antagonist

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4
Q

ospemifine MOA

A

partial ER agonist on vaginal tissue

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5
Q

tamoxifen MOA and uses

A

ER antagonist

breast cancer

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6
Q

raloxifene MOA and uses

A

ER receptor antagonist

osteoporosis

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7
Q

fulvestrant MOA and uses

A

ER receptor antagonist

precocious puberty

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8
Q

mifeprestone class, MOA and uses

A

progestin
progesteron receptor antagonist
non-surgical abortion

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9
Q

What are the 3 lactation drugs?

A

bromocriptine
metoclopramide
domperidone

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10
Q

bromocriptine MOA and uses

A

D2 agonist

hyperprolactinemia and lactation suppression

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11
Q

metoclopramide MOA and uses

A

D2 antagonist

induce lactation

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12
Q

domperidone MOA and uses

A

D2 antagonist

induce lactation

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13
Q

What are the 3 abortofacients?

A

mifepristone
misoprostol
methotrexate

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14
Q

Misoprostol MOA and uses

A

PGE1 analogue
abortion
uterine contractions
post-partum hemorrhage

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15
Q

Methotrexte MOA and uses

A

DHFR inhibitor

abortion

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16
Q

what are the 4 tocolytics?

A

terbutaline
nefidipine
magnesium sulfate
indomethacin

17
Q

6 uterotonics and induction

A
oxytocin
carboprost
methylergonovine
misoprostol
dinoprostone
PGE2