Drugs of abuse 2 and 3 Flashcards
What is the major concern with speedballs?
Sympathomimetic will wear off faster than the opioid, thus causing respiratory depression
What is a major s/sx of tramadol in overdose?
Seizures
What is a major side effect of methadone?
Prolongs QT interval
What is the onset and duration of action of methadone?
Long onset and long duration
What are the drugs that are in Lomotil? MOA of each
Atropine and Diphenoxylate (opioid receptor agonist)
What is the MOA of loperamide (imodium)?
opioid receptor agonist
What is the half-life of Naloxone compared to opioids? Significance of this?
- Shorter
- Must bolus and babysit since the effect may wear off after a few hours
What is the use of naltrexone?
Alcohol and opioid dependence
What is phenibut?
OTC herbal GABA agonist
What is the MOA of Jimsonweed?
Anticholinergic
What is the compound found in nutmeg that has hallucinogenic properties?
Myristicin
What is the MOA of ecstasy?
increases dopamine, NE, and 5HT release
Why do people who take ecstasy wear pacifiers?
Bruxism
What, generally, are “bath salts”?
Umbrella term for a family of highly addictive, synthetic stimulants
What is the only legal cathinone?
Buproprion
