drugs not to forget about Flashcards
1
Q
Bortezomib
A
proteasome inhibitor which can be used in Ab mediated rejection
inhibits breakdown of IkB so that there is lots of inhibition of NFkB which usually supports B cells and plasma cell survival
2
Q
Belatacept
A
fusion Fc of IgG1 to extracellular CTLA4- block T cell activation by binding CD80/86
3
Q
Anakinra
A
IL-1 receptor antagonist
4
Q
Basiliximab
A
anti CD 25 (which is the IL-2 receptor)
selective for activated T cells and unfortunately t regs
