C1q stuff Flashcards
1
Q
Screening
A
C4 level
cannot rule out if normal
good for between episodes as C1 inhibitor can be normal between episodes
2
Q
C1 q level low in
normal in
A
low in acquired
normal in hereditary
3
Q
C1 inhibitor level can be normal in
A
Type 2 acquired
Type 2 hereditary
4
Q
100% abnormal
A
functional C1 inhibitor assay
5
Q
Types of HAE
A
1- most common, low levels
2- dysfunctional protein, normal or increased levels
4- women, eostrogen related, not due to c cascade, due to factor XII gain of function
6
Q
Types of AAE
A
1- B cell lymphoprolif
2-Ab against C1 inhib (but note 30% HAE also have)
