Drugs involved in CyP450 metabolic system

Question 1

What are the CyP450 enzyme inhibting drugs?

Answer 1

S - Sodium Valproate
I - Isoniazid
C - Cimetidine
K - Ketoconazole
F - Fluconazole
A - Alcohol (binge drinking)
C - Chloramphenicol
E - Erythromycin
S - Sulfonamides
.
C - Ciprofloxacin
O - Omeprazole
M - Metranidazole
(Grapefruit juice and cranberry juice)

Question 2

What are the CyP450 enzyme inducing drugs?

Answer 2

S -Sulfonylureas
C - Carbamazepine
R - Rifampicin
A - Alcohol (chronic intake)
P - Phenytoin
G - Griseofulvin
P - Phenobarbital
(St. John's wort, BBQ'd meat)

Question 3

What drugs are metabolised by the CyP450 system?

Answer 3

Phenytoin             Pretty
Pethidine              Poor
Statins                   Sex
Corticosteroids    Comes
Warfarin                When
Theophylline        The
Tricyclics               Treacle
OCP                      Objects