Drugs in Blood Pressure Flashcards
Define hypertension
Elevated systemic blood pressure
Define hypertension
Elevated systemic blood pressure
What systolic blood pressure range is normal?
What diastole blood pressure range is normal?
What systolic blood pressure range is mild hypetension?
140-160
What diastolic blood pressure range is mild hypertension?
90-100
What systolic blood pressure range is severe hypertension?
> 210
What diasolic blood pressure range is severe hypertension?
> 120
What are the two kinds of hypertension?
- Primary (essential) hypertension
2. Secondary hypertension
What is the cause of primary hypertension?
Cause unknown
What is the cause of secondary hypertension?
Renal hypertension or pheochromocytoma
What are the risk factors that can lead to primary hypertension?
- Smoking
- Obesity
- Salt
- Lack of exercise
- Genetic
Why could salt lead to primary hypertension?
If you retain sodium you retain water which increases your total blood volume and therefore increases your blood pressure
What is the best way to reduce hypertension?
Reducing blood pressure
What are the fomulas used to describe how blood pressure is controlled?
Blood pressure = TPR x CO where CO = HR x SV
How does blood volume affect blood pressure?
The higher the blood volume the higher the blood pressure
Refering to the formulae for blood pressure what could you reduce in order to reduce blood pressure and therefore hypertension?
Reduce heart rate
Reduce blood volume
Reduce stroke volume
What 4 kinds of drug action could be used to lower blood pressure?
- Blocking the action of the sympathetic nervous system
- Diuretics
- Hormones
- Vasodilators
What drugs can act on B adrenoceptors and what transmitters are they blocking the action of?
Antagonists blocking the action of noradrenaline and adrenaline
What is propranolol
A non-selective B-adrenoceptor anatagonist
What is antenolol
A B1 selective antagonist
