1B Drugs

Question 1

Diuretics

Answer 1

•Increase the volume of urine produced

•eliminating excess fluids so that blood volume decreases.

•Smaller volume pumped from heart bp falls.

Question 2

Beta blockers

Answer 2

Block response of heart to hormones e.g. adrenaline
• normally act to speed up heart rate + increase bp

Question 3

Sympathetic nerve inhibitors

Answer 3

Prevent nerve signaling to arteries, which stimulate arteries to constrict, which raises bp.
Keep arteries dilated and the blood pressure low.

Question 4

Antihypertensives

Answer 4

Drugs that lower blood pressure.

Question 5

Anticoagulants

Answer 5

Warfarin
Interfere with manufacture of prothrombin.
Lower levels of prothrombin reduce clotting ability of blood.

Question 6

Platelet inhibitory drugs

Answer 6

Aspirin + Clopidogrel
Make platelets less sticky.
Reduce clotting ability of blood.

Question 7

Statins

Answer 7

• lower levels of cholesterol in blood
• block production of cholesterol + LDLs
• reduce inflammation in lining of arteries

Question 8

Plant stanols and sterols

Answer 8

• reduce blood cholesterol
• sold as food not drug
• similar in structure to cholesterol