Drugs + HLA types Flashcards
Give a name of a proton pump inhibitor
Lansoprazole
Omeprazole
Give a name of a H2 blocker
Ranitidine
Cimetidine
Give a name of a DMARD
Methotrexate
Sulfasalazine
Hydroxychloroquine
Rituximab
Give an example of an ACE inhibitor
Ramipril
Lisinopril
Give an example of an angiotensin receptor blocker
Candesartane
Eprosartan
Give an example of a calcium channel blocker
Amlodipine
Nifedipine
Give an example of an NSAID
Aspirin
Ibuprofen
Salicyclic acid
Diclofenec
Give an example of beta blocker
Atenolol
Bisoprolol
Give an example of a thiazide like diuretic
Bendroflumethazide
Give an example of a potassium sparing diuretic
Spironolactone
How do PPIs work?
Irreversible inactivate protein pumps
How do some diuretics work?
Inhibit symporters in areas of the kidney nephron so that there is reduced reabsorption of salt from the filtrate
How does heparin work?
Anticoagulant, inhibits thrombin and factor X
How do CCBs work?
Increase cGMP and reduce intracellular Ca2+
How do statins work?
Block rate limiting step in cholesterol pathway
How does aspirin work?
Irreversible inactivation of cycloxygenase (COX)
How does ibuprofen work?
Completely inhibits arachidonic acid at the active site of COX
How does penicillin work?
Inhibits transpeptidases, preventing cross linking and inhibiting bacterial wall synthesis
How do corticosteroids work?
Up regulate anti-inflammatory genes and down regulate pro-inflammatory genes
Give an example of an SSRI
Fluoxetine
What does SSRI stand for?
Selective serotonin reuptake inhibitor
Give an example of a tricyclic antidepressant
Amitryptilline