Drugs for RA

Question 1

Penicillamine

Answer 1

May decrease IL-2 and collagenase

AE: bone Marrow suppression, autoimmune disorders, taste disturbances, anorexia, N/V

Question 2

Sulfasalazine

Answer 2

Reduced inflammation

AE: nausea, fever, rash, arthalgia, hematologist disorders,

Question 3

Aurothiglucose, aurothiomalate, auranofin

Answer 3

Uncertain mechanism

AE: pruitis, rash, stomatitis, kidney damage

Question 4

Minoxycline

Answer 4

Tetracycline type antibiotic
AE: photosensitivity, dizziness
Drug inx risk

Question 5

Hydroxychloroquine

Answer 5

Antimalarial

AE: neuromuscular toxicity, N/V/D, ataxia, nervousness

Question 6

Anakinra (Kineret)

Answer 6

Blocks IL-2 receptors

AE: serious infection, local rxn, nausea, diarrhea