drugs for infections - Webster Flashcards

1
Q

antiviral drugs

A
  • acyclovir
  • amantadine
  • rimantadine
  • tamiflu
  • ribavirin
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2
Q

indications for acyclovir

A

-shingles
-cold sores
-

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3
Q

route of acyclovir

A

PO/IV

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4
Q

adverse effects of acyclovir

A
  • GI disturbance
  • HA
  • dizziness
  • hematuria
  • orthostatic hypotension
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5
Q

nursing interventions of acyclovir

A
  • pt should rise slowly d/t orthostatic hypotension
  • maintain adequate fluid intake d/t it being hard on kidneys
  • never give bolus, run over 60 mins
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6
Q

indications for amantadine

A
  • prophylactic for influenza A

- Parkinson’s

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7
Q

route of amantadine

A

PO/IV

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8
Q

adverse effects of amantadine

A
  • CNS effects

- GI disturbance

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9
Q

nursing interventions for amantadine

A
  • allergies: eggs
  • do not discontinue abruptly, may cause Parksonian crisis
  • o/d: causes CNS toxicity and arrhythmias
  • caution if driving d/t dizzines & blurred vision
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10
Q

indication for rimantadine

A

prophylactic for influenza A

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11
Q

route for rimantadine

A

PO

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12
Q

adverse effects of rimantadine

A
  • CNS
  • GI disturbance
  • orthostatic hypotension
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13
Q

nursing interventions for rimantadine

A
  • monitor BP
  • monitor BUN/Cr
  • take full course of meds to prevent resistance
  • report shortness of breath
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14
Q

indications for tamiflu

A

tx and prevent influenza A and B

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15
Q

adverse effects of tamiflu

A
-n/v/d, HA
rare
-hepatitis
-elevated liver enzymes
-rash
-Steven Johnson's syndrome
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16
Q

nursing interventions of tamiflu

A
  • monitor AST/ALT

- must take meds within 48 hours of symptoms

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17
Q

indications for ribavirin

A

-hepatitis C with IFN

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18
Q

route of ribavirin

A

inhale, PO, inj

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19
Q

route of tamiflu

A

PO

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20
Q

adverse effects of ribavirin

A
  • respiratory
  • CNS
  • GI
  • rash
21
Q

nursing interventions of ribavirin

A
  • monitor BP and RR

- should not be pregnant (Cat X)

22
Q

antifungal drugs

A
  • fungizone
  • diflucan
  • mycostatin
23
Q

indications for fungizone

A

systemic mycosis

24
Q

route of fungizone

25
adverse reactions of fungizone
- hypokalemia - fever - chills - n/v
26
nursing interventions for fungizone
- monitor BUN/Cr - monitor K/Mg level - monitor BP - report pain at injection site - give a test dose first to see reaction - very nephrotoxic, run over 6 hours - compatible with D5W - sensitive to light
27
indications for diflucan
systemic candiiasis
28
route of diflucan
PO/IV
29
adverse effects of diflucan
- HA - n/v - rash
30
nursing interventions for diflucan
- monitor BUN/Cr - monitor liver enzymes - increases Dilantin level - decreased effectiveness of Cimetidine and Rifampin - HCTZ increased effectiveness
31
indications for mycostatin
local infections of the skin and membranes
32
route of mycostatin
oral/topical
33
adverse effects of mycostatin
n/v
34
nursing interventions of mycostatin
- s/s in mouth for as long as possible - assess for skin color, rashes - keep wounds open to air - do not eat for 5-10 minutes after medication
35
antiparasitic drugs
- amebicides(Flagyl) - antimalarial agents - anthelminitics - scabicides & pediculicides
36
indications for Flagyl
- trichomoniasis - bacterial vaginosis - GI
37
route of Flagyl
PO/IV/topical
38
adverse effects of Flagyl
- rash - nausea - dysuria
39
nursing interventions of Flagyl
- urine is dark brown/reddish - avoid alcohol! - increased lithium levels - assess CNS
40
antimalarial agents
- purpose: to destroy the protozoa - focus: to kill or inhibit protein synthesis - chloroquine hcl - pyrimethamine - primaquine - quinine sulfate
41
chloroquine hcl
- hemolytic anemia d/t G6PD deficiency - affect balance and sound (cranial nerve VIII involvement) - pregnant women: spinal problems with the fetus - caution when taking liver toxic drugs
42
pyrimethamine
- taken when the area is resistant to chloroquine - depletes folic acid - don't take if kidney or liver disease - monitor for seizures
43
primaquine
- absence of WBCs | - acute hemolytic anemia
44
quinine sulfate
- pregnant women: deafness in fetus - thrombocytopenia - caution with breastfeeding - people with G6PD enzyme deficiency
45
patient education with antimalarials
Notify MD - GI upset - cranial nerve involvement - renal & cardiovascular impairment - any signs of anemia or bleeding
46
antihelminitics
- Vermox - entacyl - pin-x
47
scabicide
- Elimite: drug of choice, safe after 2 months of age | - Kwell: 2nd drug of choice, put on cool skin, do not give to pregnant women
48
pediculicides
Nix & Rid are both topical
49
contraindications for pediculicides
- hypersensitivity to Permethrin cream - cream contains formaldehyde, can cause dermatitis - chrysanthemums - allergic reaction