drugs for infections - Webster Flashcards

1
Q

antiviral drugs

A
  • acyclovir
  • amantadine
  • rimantadine
  • tamiflu
  • ribavirin
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2
Q

indications for acyclovir

A

-shingles
-cold sores
-

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3
Q

route of acyclovir

A

PO/IV

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4
Q

adverse effects of acyclovir

A
  • GI disturbance
  • HA
  • dizziness
  • hematuria
  • orthostatic hypotension
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5
Q

nursing interventions of acyclovir

A
  • pt should rise slowly d/t orthostatic hypotension
  • maintain adequate fluid intake d/t it being hard on kidneys
  • never give bolus, run over 60 mins
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6
Q

indications for amantadine

A
  • prophylactic for influenza A

- Parkinson’s

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7
Q

route of amantadine

A

PO/IV

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8
Q

adverse effects of amantadine

A
  • CNS effects

- GI disturbance

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9
Q

nursing interventions for amantadine

A
  • allergies: eggs
  • do not discontinue abruptly, may cause Parksonian crisis
  • o/d: causes CNS toxicity and arrhythmias
  • caution if driving d/t dizzines & blurred vision
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10
Q

indication for rimantadine

A

prophylactic for influenza A

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11
Q

route for rimantadine

A

PO

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12
Q

adverse effects of rimantadine

A
  • CNS
  • GI disturbance
  • orthostatic hypotension
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13
Q

nursing interventions for rimantadine

A
  • monitor BP
  • monitor BUN/Cr
  • take full course of meds to prevent resistance
  • report shortness of breath
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14
Q

indications for tamiflu

A

tx and prevent influenza A and B

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15
Q

adverse effects of tamiflu

A
-n/v/d, HA
rare
-hepatitis
-elevated liver enzymes
-rash
-Steven Johnson's syndrome
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16
Q

nursing interventions of tamiflu

A
  • monitor AST/ALT

- must take meds within 48 hours of symptoms

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17
Q

indications for ribavirin

A

-hepatitis C with IFN

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18
Q

route of ribavirin

A

inhale, PO, inj

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19
Q

route of tamiflu

A

PO

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20
Q

adverse effects of ribavirin

A
  • respiratory
  • CNS
  • GI
  • rash
21
Q

nursing interventions of ribavirin

A
  • monitor BP and RR

- should not be pregnant (Cat X)

22
Q

antifungal drugs

A
  • fungizone
  • diflucan
  • mycostatin
23
Q

indications for fungizone

A

systemic mycosis

24
Q

route of fungizone

A

IV

25
Q

adverse reactions of fungizone

A
  • hypokalemia
  • fever
  • chills
  • n/v
26
Q

nursing interventions for fungizone

A
  • monitor BUN/Cr
  • monitor K/Mg level
  • monitor BP
  • report pain at injection site
  • give a test dose first to see reaction
  • very nephrotoxic, run over 6 hours
  • compatible with D5W
  • sensitive to light
27
Q

indications for diflucan

A

systemic candiiasis

28
Q

route of diflucan

A

PO/IV

29
Q

adverse effects of diflucan

A
  • HA
  • n/v
  • rash
30
Q

nursing interventions for diflucan

A
  • monitor BUN/Cr
  • monitor liver enzymes
  • increases Dilantin level
  • decreased effectiveness of Cimetidine and Rifampin
  • HCTZ increased effectiveness
31
Q

indications for mycostatin

A

local infections of the skin and membranes

32
Q

route of mycostatin

A

oral/topical

33
Q

adverse effects of mycostatin

A

n/v

34
Q

nursing interventions of mycostatin

A
  • s/s in mouth for as long as possible
  • assess for skin color, rashes
  • keep wounds open to air
  • do not eat for 5-10 minutes after medication
35
Q

antiparasitic drugs

A
  • amebicides(Flagyl)
  • antimalarial agents
  • anthelminitics
  • scabicides & pediculicides
36
Q

indications for Flagyl

A
  • trichomoniasis
  • bacterial vaginosis
  • GI
37
Q

route of Flagyl

A

PO/IV/topical

38
Q

adverse effects of Flagyl

A
  • rash
  • nausea
  • dysuria
39
Q

nursing interventions of Flagyl

A
  • urine is dark brown/reddish
  • avoid alcohol!
  • increased lithium levels
  • assess CNS
40
Q

antimalarial agents

A
  • purpose: to destroy the protozoa
  • focus: to kill or inhibit protein synthesis
  • chloroquine hcl
  • pyrimethamine
  • primaquine
  • quinine sulfate
41
Q

chloroquine hcl

A
  • hemolytic anemia d/t G6PD deficiency
  • affect balance and sound (cranial nerve VIII involvement)
  • pregnant women: spinal problems with the fetus
  • caution when taking liver toxic drugs
42
Q

pyrimethamine

A
  • taken when the area is resistant to chloroquine
  • depletes folic acid
  • don’t take if kidney or liver disease
  • monitor for seizures
43
Q

primaquine

A
  • absence of WBCs

- acute hemolytic anemia

44
Q

quinine sulfate

A
  • pregnant women: deafness in fetus
  • thrombocytopenia
  • caution with breastfeeding
  • people with G6PD enzyme deficiency
45
Q

patient education with antimalarials

A

Notify MD

  • GI upset
  • cranial nerve involvement
  • renal & cardiovascular impairment
  • any signs of anemia or bleeding
46
Q

antihelminitics

A
  • Vermox
  • entacyl
  • pin-x
47
Q

scabicide

A
  • Elimite: drug of choice, safe after 2 months of age

- Kwell: 2nd drug of choice, put on cool skin, do not give to pregnant women

48
Q

pediculicides

A

Nix & Rid are both topical

49
Q

contraindications for pediculicides

A
  • hypersensitivity to Permethrin cream
  • cream contains formaldehyde, can cause dermatitis
  • chrysanthemums - allergic reaction