Drugs for Hypertension Flashcards

0
Q

First line drug for HPN. Can be also used in Renal Ca stones and Nephrogenic DI

A

Hydrochorothiazide

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1
Q

Drug therapy for Stage 1 Hypertension

A

Thiazide Type diuretics

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2
Q

Side effects of Hydrochlorothiazide

A

Hyperglycemia, hyperlipidemia, hyperuricemia

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3
Q

Drug of choice for hypertensive patient with pulmonary edema.

A

Furosemide

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4
Q

Activates Alpha2 adrenergic receptors. Can also be used in opiod withdrawal

A

Clonidine

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5
Q

Notable side effect of Clonidine. What is the treatment for the said SE.

A

Rebound hypertension. Taper to avoid It and administer PHENTOLAMINE

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6
Q

Drug of Choice for Pre eclampsia

A

Methyldopa

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7
Q

What is the SE of Methyldopa?

A

Hemolytic Anemia ( Positive Coombs Test)

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8
Q

A ganglion blocker which is now an obsolete treatment for HPN. It has a postural hypotension side effect

A

Hexamethonium

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9
Q

Irreversibly block the vesicular monoamine transporter

A

Reserpine

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10
Q

Side effect of Reserpine

A

Severe psychiatric depression, suicidal ideation

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11
Q

Most selective for prostatic smooth muscle and can also be used in HPN

A

Tamsulosin

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12
Q

An alpha 1 selective adrenergic antagonist that serves as both antihypertensive and Tx for BPH

A

Prazosin

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13
Q

Side effect of Prazosin

A

First Dose Hypotension

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14
Q

Has a combined alpha and beta blockade and may be used for pheochromocytoma

A

Labetolol

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15
Q

Blocks Beta1 and Beta2 receptors. Used for HPN and anginal prophylaxis.

A

Propanolol

16
Q

Drugs used to control BP in Pheochromocytoma

A

Phenoxybenzamine, Phentolamine, Labetolol

17
Q

A vasodilator that relaxes the arteriolar smooth muscle and caused drug induced lupus

A

hydralazine

18
Q

DRUGS that can cause Lupus

A

Its HIPP to have Lupus (Hydralazine, Isoniazid, Procainamide, Penicillamine)

19
Q

Used both for HPN and on Alopecia

A

Minoxidil

20
Q

Non dihydropyridine Calcium Channel Blockers

A

Verapamil, Diltiazem

21
Q

Dihydropyridine Calcium Channel Blocker

A

Nifidepine, Amlodipine, Felodipine, Nicardipine,

22
Q

Diltiazem and Verapamil spare blockag of neurotransmitter and hormone release by blocking only

A

L type channels

23
Q

Nitrates induce vasodilation by increasing amounts of;

A

cGMP

24
Q

Mode of action of Enalapril

A

Inhibits formation of Angiotensin II

25
Q

A vasodilator that is used for hypertensive emergency and has a cyanide toxicity

A

Nitroprusside

26
Q

Inhibits ACE and formation of Angiotensin II that causes cough

A

Captopril

27
Q

Examples of Angiotensin Receptor Blocker

A

Losartan, Candesartan, Valsartan, Telmisartan, Irbesartan

28
Q

Slows ventricular remodeling and increases survival in heart failure.

A

Losartan

29
Q

Reduce aldosterone levels and cause potassium retention

A

ACEI/ARBs

30
Q

Inhibits renin.

A

Aliskiren

31
Q

Accelerated form of severe HPN associated with rising blood pressure and rapidly progressing end organ damage

A

Malignant HPN

32
Q

Mngt of Malignant HPN

A

Powerful vasodilators ( nitroprusside, fenoldopam, diazoxide) combined with diuretics and beta blockers