Drugs for Hypertension Flashcards
First line drug for HPN. Can be also used in Renal Ca stones and Nephrogenic DI
Hydrochorothiazide
Drug therapy for Stage 1 Hypertension
Thiazide Type diuretics
Side effects of Hydrochlorothiazide
Hyperglycemia, hyperlipidemia, hyperuricemia
Drug of choice for hypertensive patient with pulmonary edema.
Furosemide
Activates Alpha2 adrenergic receptors. Can also be used in opiod withdrawal
Clonidine
Notable side effect of Clonidine. What is the treatment for the said SE.
Rebound hypertension. Taper to avoid It and administer PHENTOLAMINE
Drug of Choice for Pre eclampsia
Methyldopa
What is the SE of Methyldopa?
Hemolytic Anemia ( Positive Coombs Test)
A ganglion blocker which is now an obsolete treatment for HPN. It has a postural hypotension side effect
Hexamethonium
Irreversibly block the vesicular monoamine transporter
Reserpine
Side effect of Reserpine
Severe psychiatric depression, suicidal ideation
Most selective for prostatic smooth muscle and can also be used in HPN
Tamsulosin
An alpha 1 selective adrenergic antagonist that serves as both antihypertensive and Tx for BPH
Prazosin
Side effect of Prazosin
First Dose Hypotension
Has a combined alpha and beta blockade and may be used for pheochromocytoma
Labetolol
Blocks Beta1 and Beta2 receptors. Used for HPN and anginal prophylaxis.
Propanolol
Drugs used to control BP in Pheochromocytoma
Phenoxybenzamine, Phentolamine, Labetolol
A vasodilator that relaxes the arteriolar smooth muscle and caused drug induced lupus
hydralazine
DRUGS that can cause Lupus
Its HIPP to have Lupus (Hydralazine, Isoniazid, Procainamide, Penicillamine)
Used both for HPN and on Alopecia
Minoxidil
Non dihydropyridine Calcium Channel Blockers
Verapamil, Diltiazem
Dihydropyridine Calcium Channel Blocker
Nifidepine, Amlodipine, Felodipine, Nicardipine,
Diltiazem and Verapamil spare blockag of neurotransmitter and hormone release by blocking only
L type channels
Nitrates induce vasodilation by increasing amounts of;
cGMP
