Diuretics Flashcards
Site of uric acid transport?
PROXIMAL CONVOLUTED TUBULE
Major site of sodium chloride and sodium bicarbonate reabsorption (60-70%)?
PROXIMAL CONVOLUTED TUBULE
Inhibit carbonic anhydrase in PCT associated with mountain sickness and acidosis
ACETAZOLAMIDE
Site of calcium and magnesium reabsorption?
THICK ASCENDING LIMB LOOP OF HENLE
It is an ETHACRYNIC ACID that inhibits Na/K/2CL transporter in the Thick ascending loop of Henle
FUROSEMIDE
Remember OH DANG! loop diuretic toxicities
Ototoxicity Hypokalemia Dehydration Allergy to sulfa Nephritis Gout
Inhibit Na/Cl transporter in the distal convoluted tubule?
THIAZIDE DIURETICS
Remember HYPER GLUC! (Toxic thiazide)
Hyper GLYCEMIA, LIPIDEMIA, URICEMIA, CALCEMIA
Mannitol retains water in tubule by reducing reabsorption in?
PROXIMAL TUBULE
DESCENDING LOOP
COLLECTING TUBULES
Remember DACKS!!!!!! Gynecomastia
DIGOXIN ALCOHOL CIMETIDINE KETOCONAZOLE SPIRONOLACTONE
Primary site of acidification of urine?
COLLECTING TUBULE
A potassium sparing diuretics that is an inhibitor of cytoplasmic aldosterone receptor in cortical collecting ducts
SPIRONOLACTONE
Diuretic that side effect is GYNECOMASTIA
SPIRONOLACTONE
Mannitol retains water in tubule by reducing reabsorption in?
PROXIMAL TUBULE
DESCENDING LOOP
COLLECTING TUBULES
Remember DACKS!!!!!! Gynecomastia
DIGOXIN ALCOHOL CIMETIDINE KETOCONAZOLE SPIRONOLACTONE