Drugs and Diseases: muscle Flashcards
1
Q
what are markers of cardiac injury? which is used more and why?
A
Troponin I and T, creatine kinase
Troponin used more b/c detectable earlier, peaks earlier, lasts longer
2
Q
action of metformin and what is it used to treat?
A
treats T2DM
activates AMP-PK by activating upstream kinase LKBI
3
Q
in what enzymes can one get inborn errors of metabolism in related to creatine phosphate metabolism?
A
- AGAT
- GAMT
- creatine transporter
4
Q
what is used as a gauge for measuring other substances in urine?
A
creatinine
5
Q
what can potentially be used to help treat T2DM?
A
carnitine - may improve insulin sensitivity by decreasing fat in muscles + may decrease serum glucose by increasing its oxidation in cells
