Drugs and Diseases: inflammation Flashcards

1
Q

4 cardinal signs of inflammation

A
  1. rubor (redness)
  2. calor (heat)
  3. tumor (swelling)
  4. dolor (pain)
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2
Q

significance of triene:tetraene ratio?

A

marker for essential FA deficiency

value > 0.4 indicates deficiency

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3
Q

fxn of the following NSAIDS: aspirin, acetaminophen, ibuprofen?

A

aspirin: irreversible inhibitor of COX
acetaminophen: inhibitor of COX3?
ibuprofen: reversible competitive inhibitor of COX

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4
Q

what are two drugs that are COXII inhibitors? which was taken off market?

A

celecoxib (celebrex) and rofecoxib (vioxx)

vioxx

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