Drugs against parasites Flashcards

1
Q

Heavy metals

A

bind to -SH groups on proteins

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2
Q

Quinolines

A

Block nuclei acid synthesis by intercalating in dsDNA

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3
Q

Quinones

A

blocks pyrimidine synthesis

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4
Q

Folate antagonists

A

block folate which is a necessary factor for nucleotide synthesis

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5
Q

Imidazoles

A

alkylate DNA

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6
Q

Benzimidazole

A

inhibits fumarate reductase which in necessary for anaerobic respiration
-great against helminths

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7
Q

Avermectins

A

cause paralysis of worm

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8
Q

Praziquantel

A

anti-helminthic

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