Drugs against parasites Flashcards
1
Q
Heavy metals
A
bind to -SH groups on proteins
2
Q
Quinolines
A
Block nuclei acid synthesis by intercalating in dsDNA
3
Q
Quinones
A
blocks pyrimidine synthesis
4
Q
Folate antagonists
A
block folate which is a necessary factor for nucleotide synthesis
5
Q
Imidazoles
A
alkylate DNA
6
Q
Benzimidazole
A
inhibits fumarate reductase which in necessary for anaerobic respiration
-great against helminths
7
Q
Avermectins
A
cause paralysis of worm
8
Q
Praziquantel
A
anti-helminthic