DRUGS: ABX

Question 1

augmentin

Answer 1

class: beta lactam
MOA: inhibit cell wall synthesis
S/E:
1. rash
2. diarrhoea
3. allergy

Question 2

Ciprofloxacin

Answer 2

class: 2nd gen fluoroquinolones

USE: UTI

MOA: inhibit DNA synthesis

1. n&v, diarrhoea
2. headache
3. restlessness
4. pain & inflammation @ site
5. anaphylaxis
6. tendon rupture
7. photosensitivity
8. seizure
9. peripheral neuropathy
10. hepatotoxicity

Question 3

Fosfomycin

Answer 3

novel class
MOA: inhibit cell wall synthesis
USE: UTI (specific)

nausea, diarrhoea
back pain
headache
anaphylaxis
superinfection

Question 4

Nitrofurantoin

Answer 4

MOA: disrupt nucleic acid synthesis
Use: UTI (specific)

n&v, anorexia
dark brown urine
anaphylaxis
superinfection
hepatic necrosis
steven-johnson syndrome