Drugs Flashcards
What is Metformin, what does it do?
Oral Hypoglycaemic agent
reduces gluconeogenesis in the liver
Give an example of a sulphonpurea, what is its’ action?
Tolbutamide
binds to SU elements on K+ VGC’s, releasing insulin
AND increases sensitivity of insulin receptors
Give an example of a thiazolidinedione, how does it work?
pioglitazone
binds to TF’s, increasing fatty acid + glucose uptake
Name a class of DPP-4 inhibtitors and a specific example
Gliptins
Linagliptin
1 example of a GLP-1 agonist would be?
Exenatide
Name an alpha-glucosidase inhibitor, what does it do?
Acarbose
decreases GI carb absoption
Name and SGLT2 inhibitor, how does it work?
Canaglifozin
increase glucose loss from PCT
Give 2 examples of thioamides, their action and specific side effects
inhibit thyroperoxidase
carbimazole - argranulocytosis
propylthiouracil - liver disease
What is Orlistat?
inhibits GI lipase
What is atropine?
What is a side-effect of its’ use?
A muscarinic antagonist
produces dry mouth
What is Propranolol and what is it used for?
a Beta adrenoreceptor antagonist
What is chloramphenicol?
Who is it contraindicated for and why?
An antibiotic
Those under 3 months old because they have insufficient gluconyltransferase activity
Give 3 examples of anti TB drugs
Ethambutol
Rifamipicin
Cyloserine
Name one side-effect of Ethambutol
Red-green colour blindness
Name one side-effect of Rifamipicin
orange-red saliva and urine
