Drugs Flashcards
1
Q
fluoroquinolone antibiotics
A
- eg levofloxacin
- common to treat community acquired pneumonia
- inhibit bacterial topoisomerase
- can prolong QT interval on ECG
- unsafe in pregnancy
2
Q
rifampin
A
- inhibits bacterial RNA polymerase
* used for tuberculosis
3
Q
actinomycin D
A
•used in chemotherapy to inhibit RNA polymerase -> blunts replication of cancer cells
4
Q
protein synthesis inhibitor antibiotics
A
- ie aminoglycosides
* target ribosomes of the size found only in bacteria