Drugs Flashcards
SSRI’s
- fluoxetine (prozac)
- sertraline (zoloft)
- paroxetine (paxil)
- citalopragm (celexa)
- escitalopram (lexapro)
- luvaxamine (luvox)
When should you take SSRI’s?
In the morning
- they tend to be activating
Timelines for SSRI therapy?
Depression 2-6 weeks
Panic d/o 4-8 weeks
OCD 6-12 weeks
Common SSRI SE?
HA Nausea Tinnitus Insomnia Nervousness Akathisia (agitation, restless) Bleeding Sexual se
Why do SSRI’s cause bleeding?
They effect platelet serotonin levels -> abnormal bleeding
Withdrawal symptoms of SSRI’s?
Dizziness Paresthesias Dysmorphic mood Agitaiton Flu-like
Which SSRI’s are more likely to cause withdrawal symptoms?
Short acting SSRI
Paroxetine (Paxil) has the shortest 1/2 life
Fluoxetine is the longest acting (4-6 days)
SSRI and pregnancy?
Nope
Fluoxetine (prozac) may cause?
Drowsiness
Paroxetine is aka?
Paxil
Paroxetine (paxil) may cause?
Drowsiness
Citalopram is aka?
Celexa
Citalopram (celexa) is best for what type of pt?
Safer w warfarin so anyone on blood thinners
Escitalopram is aka?
Lexapro
Luvaxamine isa aka?
Luvox
common SNRI se?
Milld tachycardia HTN Sexual se Mydriasis Urinary constriction Abnormal bleeding
What are the SNRIs?
Venlafaxine
Duloxetine
Venlafaxine is aka?
Effexor
Venlafaxine (effexor) lacks?
Significant anticholinergic s/e
Venlafaxine (effexor) is not good for?
BP
Duloxetine is aka?
Cymbalta
Duloxetine (cymbalta) is not good for?
BP
TCA common SE?
Anticholinergic effect Cardiac effects Lower seizure threshold Loss of libido Sexual dysfunction
Must taper
Cardiac effects of TCA’s?
Function of anticholinergic and direct myocardial depression
- altered rate,
- rhythm,
- contractility
Esp w preexisting cardiac disease
- bundle branch block