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Fundamentals of Cellular Medicine > DRUGs > Flashcards

DRUGs Flashcards

1
Q

Penicillins

A
  1. MOA: CWI
  2. S vs. C: Bactericidal
  3. PD: Time dependent
  4. Spectrum: Narrow to Broad
  5. Uses:
    1. RTI
    2. STI
    3. Skin
    4. Urinary
    5. IA
    6. Blood Meningitis
  6. Adverse Effects:
    1. GI
    2. Rash/Allergy
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2
Q

Cephalosporins

A
  1. MOA: CWI
  2. S vs. C: Bactericidal
  3. PD: Time dependent
  4. Spectrum: Narrow to VERY Broad
  5. Uses:
    1. RTI
    2. STI
    3. Skin
    4. Urinary
    5. IA
    6. Blood Meningitis
  6. Adverse Effects:
    1. GI
    2. Rash/Allergy
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3
Q

Monobactams

A
  1. MOA: CWI
  2. S vs. C: Bactericidal
  3. PD: Time dependent
  4. Spectrum: Gram (-) only
  5. Uses:
    1. Severe Beta Lactam Allergy
  6. Adverse Effects:
    1. GI
    2. Rash/Allergy
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4
Q

Carbapenems

A
  1. MOA: CWI
  2. S vs. C: Bactericidal
  3. PD: Time dependent
  4. Spectrum: Very Broad
  5. Uses:
    1. Held in reserve for serious, life threatening infections
  6. Adverse Effects:
    1. GI
    2. Rash/Allergy
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5
Q

Glycopeptides

A
  1. MOA: CWI
  2. S vs. C: Bactericidal
  3. PD: Time dependent
  4. Spectrum: Gram (+)
  5. Uses:
    1. MRSA
  6. Adverse Effects:
    1. Nephrotoxicity
    2. Ototoxicity
    3. Red-Man Syndrome
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6
Q

Lipopeptides—Daptomycin

A
  1. MOA: CMI
  2. S vs. C: Bactericidal
  3. PD: Concentration Dependent
  4. Spectrum: Gram (+)
  5. Uses:
    1. MRSA
  6. Adverse Effects:
    1. Myopathy
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7
Q

Cationic Proteins—Polymixins

A
  1. MOA: CMI
  2. S vs. C: Bactericidal
  3. PD: Concentration Dependent
  4. Spectrum: Gram (-)
  5. Uses:
    1. Multi-Drug Resistant
  6. Adverse Effects:
    1. Nephrotoxicity
    2. Neurotoxicity
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8
Q

Fluoroquinolones

A
  1. MOA: DNA Inhibitors
  2. S vs. C: Bactericidal
  3. PD: Concentration Dependent
  4. Spectrum: Broad
  5. Uses:
    1. RTI
    2. STI
    3. Skin
    4. UTI
  6. Adverse Effects:
    1. GI
    2. CNS Stimulation
    3. Photosensitivity
  7. Black Box Warning
    1. Cartilage Malformation
    2. Tendon Rupture
    3. Peripheral Neuropathy
    4. Prolonged QT
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9
Q

Macrolides

A
  1. MOA: PI 50S
  2. S vs. C: Bacteriostatic
  3. PD: Time dependent
  4. Spectrum: Gram (+) and Atypicals
  5. Uses:
    1. RTI
    2. STI
    3. Skin
  6. Adverse Effects:
    1. GI
  7. Black Box Warning:
    1. Prolonged QT
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10
Q

Lincosamides, Clindamycin

A
  1. MOA: PI 50S
  2. S vs. C: Bacteriostatic
  3. PD: Time dependent
  4. Spectrum: Gram (+) plus Anaerobes
  5. Uses:
    1. Beta Lactam Allergy
  6. Adverse Effects:
    1. GI
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11
Q

Chloramphenicol

A
  1. MOA: PI 50S
  2. S vs. C: Bactericidal/Bacteriostatic
  3. PD: Time dependent
  4. Spectrum: Broad
  5. Uses:
    1. Toxic: Reserve
  6. Adverse Effects:
    1. Anemia
    2. Gray baby syndrom
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12
Q

MAOI: Linezolid

A
  1. MOA: PI
  2. S vs. C: Bacteriostatic
  3. PD: Time dependent
  4. Spectrum: Gram (+)
  5. Uses:
    1. MRSA
  6. Adverse Effects:
    1. GI
    2. CNS
    3. Myelosuppression
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13
Q

Aminoglycosides

A
  1. MOA: PI 30 S
  2. S vs. C: Bactericidal
  3. PD: Concentration Dependent
  4. Spectrum: Gram (-)
  5. Uses:
    1. Serious Hospital Infections: Synergy
  6. Adverse Effects:
    1. Neurotoxicity
    2. Nephrotoxicity
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14
Q

Tetracyclines/Glycyclines

A
  1. MOA: PI 30S
  2. S vs. C: Bacteriostatic
  3. PD: Time dependent
  4. Spectrum: Broad and Atypicals
  5. Uses:
    1. RTI
    2. Tick borne
    3. MDRO
  6. Adverse Effects:
    1. GI
    2. Rash/Allergy
    3. Photosensitivity
  7. Black Box Warning
    1. Arthropathy
    2. Teeth Discoloration
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15
Q

Sulfonamides

A
  1. MOA: Folate/Metabolic Inhibitors
  2. S vs. C: Bactericidal
  3. PD: Time dependent
  4. Spectrum: Broad
  5. Uses:
    1. UTI
    2. PiP
    3. Toxo
  6. Adverse Effects:
    1. GI
    2. Rash/Allergy
    3. Photosensitivity
    4. Mylosuppression
  7. Black Box Warning
    1. Don’t give to 3rd Trimester or newborns
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16
Q

Nitrofurantoin

A
  1. MOA: ACoA
  2. S vs. C: Bactericidal
  3. PD: Time dependent
  4. Spectrum: Narrow
  5. Uses:
    1. UTI
    2. E. Coli
  6. Adverse Effects:
    1. GI
    2. Rash/Allergy
    3. Pulmonary

Fundamentals of Cellular Medicine (7 decks)

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