Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Microbiology > Drugs > Flashcards

Drugs Flashcards

1
Q

penecillin

A

inhibits cell wall synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how does penecillin work

A

B lactam ring
prevents cross link of polypeptides interfere with cell wall construction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

cycloserine

A

targets cell wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how does cycloserine work

A

inhibits side chain on NAM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

bacitracin

A

targets cell wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

use of bacitracin

A

topic application against gram positive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

how does bacitracin work

A

bind to bactoprenol lipid carrier
inhibits transport of peptidoglycan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

vancomycin

A

targets cell wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

use of vancomycin

A

last line against MRSA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how does vancomycin work`

A

inhibit peptide side chain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

cephalosporin

A

target cell wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how does cephalosporin work

A

different b lactam
inhibit cross link of peptide side chain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

teixobactin

A

inhibits cell wall synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

use of teixobactin

A

against resistant gram positives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how does teixobactin work

A

inhibit cross link of peptide side chain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

isoniazid

A

inhibits cell wall synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

how does isoniazid work

A

inhibits mycolic acid synthesis in mycobacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

ethambutol

A

inhibits cell wall synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

how does ethambutul work

A

inhibits incorporation of mycolic acid into cell wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

nitrofuritan

A

inhibits protien synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

use of nitrofuritian

A

treat UTIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

how does nitrofuritan work

A

attack bacterial ribosomal protiens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

chloramphenical

A

inhibits protien synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

use of chloramphenical

A

suppress bone marrow and affect blood cell form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
how does chloromphenical work
inhibit peptide bond formation bind to 50S of 70S
26
aminoglycosides
inhibit protien synthesis
27
what can aminoglycosides do
cause auditory damage
28
how does aminoglycoside work
change shape of 30S of 70S ribosome
29
tetracyclines
inhibit protien synthesis broad spectrum
30
how does tetracycline work
interfere with TRNA attachment to ribosomes
31
glycylcyclines
inhibit protien synthesis
32
use of glycylclines
MRSA and multi drug resistance actinobacter baumannii
33
what do glycylclines do
bind to 30S ribosomal sub inhibit rapid efflux intravenous
34
macrolides
inhibit protien synthesis
35
what do macrolides do
used against gram positive have macrocyclic lactone ring
36
streptogramins
inhbit protien synthesis
37
how does streptogamins work
attach to 50S subunit
38
use of streptogamin
gram positive resistant to others
39
oxazolidinones
inhibit protien synthesis
40
how do oxazolidinones work
bind to 50s/30s subunit interface
41
use of oxazolidinones
synthetic MRSA
42
pleuromutilins
inhibit protien synthesis
43
what are pleuromutilins used for
topic, gram positive retapamulin
44
daptomycin
injury to membrane
45
what does daptomycin do
attack bacterial cell membrane produced by streptomyces
46
polymycin B and E
injury to membrane
47
what does polymyxin B and E do
topical, bactericidal synthesis of membrane
48
Rifamycin
inhibits nucleic acid synthesis
49
how does rifamycin work
inhibit mrna penetrates tissue, antitubercular activity
50
quinolone/ fluoroquinolone
inhibits nucleic acid synthesis
51
what does quinolone/ fluoroquinolone do
inhibits nucleic acid synthesis nalioxic acid: inhibit DNA gyrase gemi/moxi: newer version
52
sulfonamides
inhbit nucleic, folic and protien acid synthesis
53
how do sulfonamides work
inhibit synthesis of folic acid need NA and protien synthesis
54
what does sulfonamide bind to enzymes to do
PABA -> dihydro acid
55
polyenes
affect fungal sterols
56
how do polyenes work
interrupts synthesis of ergosterols, making membrane excessively permeable
57
azoles
affect fungal sterols
58
use of azoles
imidorzoles: cutaenous mycoses triazole: systemic fungi
59
how do azoles work
interrupt synthesis of ergosterols, making the membrane excessively permeable
60
allylamines
affect fungal sterols
61
what do allylamines do
interrupt synthesis of ergosterols, making membrane permeable
62
echinocandins
affect fungal cell wall
63
what do echinocandins do
inhibit synthesis of B glucan
64
flucytosine
inhibit nucleic acid
65
griseofluvin
inhibit mitosis
66
what do griseofluvin do
inhibit formation of microtubules produced by penecillin
67
tolnafate
inhibit nucleic acid synthesis
68
use of tolnafate
atheletes foot
69
pentamidine
inhibit nucleic acid synthesis
70
use of pentamidine
anti-pneumocystis
71
what can pentamidine do
bind to dna
72
protease inhibitors
inhibits assembly
73
use of protease inhibitors
paxlovid - COVID 19
74
what do protease inhibitors do
block cleavage of protien precursors
75
exit inihibits
inhibits neuroaminidase, required for some viruses to bud from host cell
76
interferions
inhibit spread
77
how are interferons produced
viral infected cells Imiquids: promotes it
78
antiretrovirals
interfere with replication
79
how does antiretrovirals work
RNA
80
quinone and chloroquine (antiprotozoan)
interfere with digestion of hemoglobin
81
use of quinone and chloquine
malaria
82
artemisinin (antiprotozoan)
kills plasmodium
83
use of artemisinin
malaria
84
what do metronidazole, tinidazole, nitazoxanide work against
trichomas, giardiasis, amebic dysentry
85
metronidazole tinidazole nitazoxanide (antiprotozoan)
interferes with anaerobic bacteria
86
miltefosine (antiprotozoan)
inhibits cytochrome oxidase in mitochondria
87
what is miltedosine used for
ambeic encephalitis leishmaniasis
88
niclosamide (antihelminth)
prevents atp production
89
niclosamide use
tapeworms
90
praziquantel (antihelminth)
alter membrane permeability
91
praziquantel use
tapeworms, flukes
92
mebendazole, albendazole
interfere with intestinal helminths
93
ivermectin
paralysis of helminths
94
use of ivermectin
roundworm, mites

Microbiology (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions