Drugs Flashcards

1
Q

Side effects of ethosuximide Plus MOA

A
EFGHIJ 
Ethosuximide 
fatigue 
G.I. distress 
headache 
itching 
SJS     Works on T type calcium channels
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2
Q

Lamotrigine

A

Blocks Na channels plus glutamate

Lamborghini hates salt plus glue

SJS titrate slowly
Hemophagocytic lymphohistiocytosis

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3
Q

Why does propofol have a rapid onset and duration

A

Lipophilic drugs rapidly defuse with to organs with high blood flow.

Sequence first brain heart liver kidneys next skeletal muscle and skin next bone & fat

Eliminated

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4
Q

Medication induced delirium

A

Examples psychoactive agents example anticholinergics ,antihistamines benzodiazepines, sedative , hypnotics opioids

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5
Q

Anti-seizure medication’s that block and Na channels

A

Phenytoin carbamazepine

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6
Q

Anti-seizure medication that block sodium channels but increase, GABAproduction

A

Valproic acid

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7
Q

Drugs that increase, GABA action

A

Benzodiazepines phenobarbital

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8
Q

How does Levetiracetam work

A

Modulates GABA and glutamate release

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9
Q

How does work ethosuximide

A

Blocks thalamic T type calcium channels

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