Adult primary brain tumors

Question 1

Butterfly Glioma

Answer 1

Glioblastoma multiforme

Most common malignant tumor of the brain
grade 4 astrocytoma

location: cerebral hemispheres can cross the corpus callosum

cause epidermal growth factor receptor

Labs: GFAP+
Pseudopalisaiding pleomorphic tumor cells central area of necrosis hemorrhage and or microvascular proliferation

Question 2

Frontal lobe tumor calcification

Answer 2

Oligodendroglioma

histology -oligodendrocyte origin

fried egg nucleus with clear cytoplasm chicken wire capillary pattern