drug therapy Flashcards
antipsychotics
typical antipsychotics
atypical antipsychotics
typical antipsychotics
created in 1950s
taken orally
known as dopamine antagonists as they reduce the levels of dopamine in the brain by blocking dopamine receptors
dopamine levels build up but over time production decreases and reduces positive symptoms
have a sedating effect on patients and can be used in hospitals to calm patients down
typical antipsychotics examples
chlorpromazine
pimozide
atypical antipsychotics
created in 1970s
have less side effects than typical antipsychotics
can treat both positive and negative symptoms
act on serotonin and glutamate receptors
useful in treating those at risks of suicide
atypical antipsychotics examples
clozapine
risperidone
evaluation of drug therapy
side effects
evidence
dopamine
side effects (DRUG THERAPY EVALUATION)
there are many side effects including agitation and weight gain
many stop taking the drugs because of this
evidence (DRUG THERAPY EVALUATION)
Meltzer (2012)
- found that clozapine is more effective than typical and atypical antipsychotics
- it reduced symptoms in 30-50% of patients who did not improve with typical antipsychotics
dopamine (DRUG THERAPY EVALUATION)
we do not fully understand why these drugs work
recent research suggests that low levels rather than high levels of dopamine could cause schizophrenia
they may not be the best treatment for all