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Pharm Drug Table > Drug Table - Topoisomerase Inhibitors > Flashcards

Drug Table - Topoisomerase Inhibitors Flashcards

1
Q

Etoposide (Etopophos) class

A

Epipodophyllotoxins

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2
Q

Etoposide (Etopophos) mechanism

A

Inhibits topoisomerase II

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3
Q

Etoposide (Etopophos) Therapeutics

A

Testicular carcinoma, lung cancer, and

non-Hodgkin’s lymphoma

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4
Q

Etoposide (Etopophos) other side effects

A

Dose-limiting myelosuppression

(neutropenia), oral mucositis

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5
Q

Teniposide (Vumon) Class

A

Epipodophyllotoxins

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6
Q

Teniposide (Vumon) Mechanism

A

Inhibits topoisomerase II

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7
Q

Teniposide (Vumon) Therapeutics

A

ALL

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8
Q

Teniposide (Vumon) Other side effects

A

Dose-limiting myelosuppression

(neutropenia), oral mucositis

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9
Q

Irinotecan (Camptosar) Class

A

Camptothecin

analogs

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10
Q

Irinotecan (Camptosar) Mechanism

A

Inhibits topoisomerase I

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11
Q

Irinotecan (Camptosar) Therapeutics

A

Advanced colorectal cancer; lung,

ovarian, cervical and brain tumors

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12
Q

Irinotecan (Camptosar) Other side effects

A

Severe neutropenia, severe

diarrhea

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13
Q

Topotecan (Hycamtin) Class

A

Camptothecin

analogs

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14
Q

Topotecan (Hycamtin) Mechanism

A

Inhibits topoisomerase I

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15
Q

Topotecan (Hycamtin) Therapeutics

A

Ovarian and small cell lung cancer

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16
Q

Topotecan (Hycamtin) Other side effects

A

Severe neutropenia, severe

diarrhea

Pharm Drug Table (11 decks)

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