Drug Side effects Flashcards
Nephrotoxic Medications
Abx - Gentamicin, Vancomycin, tetracyclines
NSAIDS
ACE inhibitors
IV contrast
Contraindicated in Asthma
B-blockers
Caution NSAIDS
Drugs causing Cholestasis
Flucloxacillin, coamoxiclav, nitrofurantoin, steroids and sulphonylureas
Drugs causing Hepatitis/cirrhosis
Paracetamol overdose, statins, rifampicin
ACE Inhibitors
Dry cough, nephrotoxic, hyperkalaemia
Drugs with anti-muscanaric side effects
E.g. blurred vision, urinary retention, consipation
Amytriptyline and other TCAs
cylcizine
Drug induced neutropenia
Clozapine
Carbimazole
Worsening Parkinsons Sx
Haliperidol
Metaclopramide
N.B. Domperidone = Safe as doesn’t cross BBB
Toxic epidermal necrosis
SE of peniciliins
Galactorrhea
- metoclopramide, domperidone
- phenothiazines - clorpromazine
- haloperidol
- very rare: SSRIs, opioids
Gynacomastia
Spironolactone Isonazid Ranitidine/cimitedine Chlorpromazine Digoxin
Agranulocytosis
Clozapine Carbimazole Sulfasalazine NSAIDS Quinine
SEs Testosterone therapy
Male infertility - surpresses Gnrh which decreases LH and FSH and therefore less spermproduced Acne BPH Breast tenderness Mood fluctuations