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Pharmacology > drug reactions > Flashcards

drug reactions Flashcards

1
Q

coronary vasospasm

A

cocaine
sumatriptan
ergot alkaloids

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2
Q

cutaneous flushing

A

vancomycin
adenosine
niacin
CCBs

VANC

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3
Q

dilated cardiomyopathy

A

doxorubicin (adriamycin)

daunorubicin

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4
Q

torsades de pointes

A

class III (sotalol) and class IA (quinidine) antiarrythmics

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5
Q

agranulocytosis

A

Agranulocytosis Could Certainly Cause Pretty Major Damage

Clozapine
Carbamazepine
Colchicine
Propylthiouracil
Methimazole
Dapsone
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6
Q

aplastic anemia

A 
chloramphenicol
benzene
NSAIDs
propylthiouracil
methimazole
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7
Q

direct coombs-positive hemolytic anemia

A

methyldopa

penicillin

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8
Q

gray baby syndrome

A

chloramphenicol

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9
Q

hemolysis in G6PD-deficient patients

A

hemolysis IS PAIN

Isoniazid
Sulfonamides
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin
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10
Q

megaloblastic anemia

A

having a BLAST with PMS

Phenytoin
Methotrexate
Sulfa drugs

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11
Q

thrombotic complications

A

OCPs

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12
Q

cough

A

ACE-I

*use ARBs (-sartans) instead

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13
Q

pulmonary fibrosis

A

it’s hard to BLAB when you have pulmonary fibrosis

BLeomycin
Amiodarone
Busulfan

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14
Q

acute cholestatic hepatitis, jaundice

A

erythromycin

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15
Q

focal to massive hepatic necrosis

A

liver HAVAc

Halothane
Amanita phalloides
Valproic acid
Acetaminophen

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16
Q

hepatitis

A

isoniazid

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17
Q

pseudomembranous colitis

A

clindamycin

ampicillin

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18
Q

adrenocortical insufficiency

A

glucocorticoid withdrawal (HPA suppression)

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19
Q

gynecomastia

A

Some Drugs CrEate Awkward Knockers

Spironolactone
Digitalis
Cimetidine
Estrogens
chronic Alcohol use
Ketoconazole
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20
Q

hot flashes

A

tamoxifen

clomiphene

21
Q

hyperglycemia

A 
niacin
tacrolimus
protease inhibitors
HCTZ
corticosteroids
22
Q

hypothyroidism

A

lithium
amiodarone
sulfonamides

23
Q

fat redistribution

A

glucocorticoids

protease inhibitors

24
Q

gingival hyperplasia

A

phenytoin

verapamil

25
Q

gout

A

furosemide
thiazides
niacin
cyclosporine

26
Q

myopathies

A

Fish N CHIPS Give you myopathies

Fibrates
Niacin
Colchicine
Hydroxychloroquine
IFN-a
Penicillamine
Statins
Glucocorticocoids
27
Q

osteoporosis

A

corticosteroids

heparin

28
Q

photosensitivity

A

SAT for a photo

Sulfonamides
Amiodarone
Tetracycline

29
Q

rash (SJS)

A

bad rash after a PEC SLAPP

Penicillin
Ethosuximide
Carbamazepine
Sulfa drugs
Lamotrigine
Allopurinol
Phenytoin
Phenobarbital
30
Q

SLE-like syndrome

A

it’s not HIPP to have lupus

Hydralazine
Isoniazid
Procainamide
Phenytoin

31
Q

teeth (kids)

A

tetracyclines

32
Q

tendonitis, tendon rupture, cartilage damage

A

fluoroquinolines

33
Q

diabetes insipidus

A

lithium

demeclocycline

34
Q

fanconi’s syndrome

A

expired tetracycline

35
Q

hemorrhagic cystitis

A

cyclophosphamide
ifosfamide

(prevent by coadministering with mesna)

36
Q

interstitial nephritis

A

methicillin
NSAIDs
furosemide

37
Q

SIADH

A

carbamazepine

cyclophosphamide

38
Q

cinchonism

A

quinidine

quinine

39
Q

parkinson-like syndrome

A

antipsychotics
reserpine
metoclopramide

40
Q

seizures

A

with seizures, I BITE My tongue

Isoniazid
Bupropion
Imipenem/cilastatin
Tramadol
Enflurane
Metoclopromide
41
Q

tardive dyskinesia

A

antipsychotics

42
Q

antimuscarinic

A

atropine
TCAs
H1-blockers
neuroleptics

43
Q

disulfiram-like reaction

A

metronidazole
certain cephalosporins
procarbazine
1st gen sulfonureas

44
Q

nephrotoxicity/ototoxicity

A

aminoglycosides
vancomycin
loops diuretics
cisplatin

45
Q

P450 inducers (+)

A

Most Barbies Steals Phen-phen and Refuse Greasy Carbs Chronically

Modafinil
Barbiturates
St. John's wort
Phenytoin
Rifampin
Griseofulvin
Carbamazepine
Chronic alcohol use
46
Q

P450 inhibitors (-)

A

MAGIC RACKS in GQ

Macrolides
Amiodarone
Grapefruit juice
Isoniazid
Cimetidine
Ritonavir
Acute alcohol abuse
Ciprofloxacin
Ketoconazole
Sulfonamides
Gemfibrozil
Quinidine
47
Q

Sulfa drugs

A

Popular FACTSSS

Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonamide antibiotics
Sulfasalazine
Sulfonylureas
48
Q

Sulfa drugs: allergy

A 
fever
UTI
pruritic rash
Stevens-Johnson syndrome
hemolytic anemia
thrombocytopenia
agranulocytosis
urticaria

mild => life threatening

Pharmacology (10 decks)

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