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STEP 1: pharmacology > Drug reactions 2 > Flashcards

Drug reactions 2 Flashcards

1
Q

MSK: fat redistribution

A

Glucocorticoid

Protease inhibitors

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2
Q

MSK: gingivial hyperplasia

A

Phenytoin
Verapamil
Cyclosporin

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3
Q

MSK: gout

A

Furosemide
Thiazide,
Niacin
Cyclosporine

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4
Q

MSK: myopathies

A 
Fibrates
Niacin
Colchicine
Hydroxychloroquine
Interferon alpha
Penicillamine
Statins
Glucocorticoid

“Fish N CHIPS Give you myopathies”

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5
Q

MSK: Osteoporosis

A

Corticosteroids

Heparin

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6
Q

MSK: Photosensitivity

A

Sulfonamide
Amidoraone
Tetracycline

“SAT for a photo”

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7
Q

MSK: Rash (SJS)

A 
Penicillin
Ethosuximide
Carbapazepine,
Sulfa drugs
Lamotrigine
Allopurinol
Phenytoin
Phenobarbital

“Bad rash after a PEC SLAPP”

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8
Q

MSK: SLE like syndrome

A

Hydralazine
INH
Procainamide
Phenytoin

“It is not HIPP to have lupus”

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9
Q

MSK: tendonitis, rupture, and cartilage damage

A

Fluoroquinolone

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10
Q

Renal: diabetes insipidus

A

Lithium

Demeclocycline

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11
Q

Renal: falconi’s syndrome

A

Expired tetracyclin

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12
Q

Renal: hemorrhagic cystitis

A

Cyclophoshamide

Ifosfamide (prevented by coadministering with mesna)

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13
Q

Renal: interstitial nephritis

A

Methicillin
NSAIDS
Furosemides

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14
Q

Renal: SIADH

A

Carbamazapine

Cyclophosphamide

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15
Q

Neuro: cinchonism

A

“cinchonism: due to too much quinine, flushed and sweaty skin, ringing of the ears (tinnitus), blurred vision, impaired hearing, confusion, reversible high-frequency hearing loss, headache, abdominal pain, rashes, drug-induced lichenoid reaction (lichenoid photosensitivity),[1] vertigo, dizziness, dysphoria, nausea, vomiting and diarrhea.”

Quinidine
Quinine

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16
Q

Neuro: Parkinson like syndrome

A

Antipsychotic
Reserpine
Metoclopramide

17
Q

Neuro: seizures

A 
INH
Bupropion
Imipenem/cilastatin,
Tramadol
Enfurane
Metoclopramide

“With seizures, I BITE My tongue”

18
Q

Neuro: Tardive dyskinesia

A

Antipsychotics

19
Q

Multiorgan: antimuscarinic

A

Atropine
TCA,
H1 blockers
Neuroleptics

20
Q

Multiorgan: disulfram like reaction

A

Metronidazole
Certain cephalosporins
Procabazine
1st generation sulfonylureas

21
Q

Multiorgan: nephrotoxic and ototoxic

A

Aminoglycosides
Vancomycin
Loop diuretics
Cisplatin

22
Q

P450 inducers

A 
Modafinil
Barbiturates
St Johns' wort
Phentyoin
Rifampin
Griseofulvin
Carbamazepine
Chronic alcohol use

“Momma Barb Steals Phen-phen and Refuses Greasy Carb Chronically”

23
Q

P450 inhibitors

A 
Macrolides
Amiodarone
Grapefruit juice
INH
Cimetidine
Ritonavir
Acute alcohol abuse
Cipro
Ketoconazole
Sulfonamides
Gemfibrozil
Quinidine

“MAGIC RACKS in GQ”

24
Q

Sulfa drugs

A 
Probenecid
Furosemide
Acetazolamide
Celecoxib
Thiazides
Sulfonamide Abx
Sulfasalazine
Sulfonylureas

If allergic, develop fever, UTI, pruritic rash, SJS, hemolytic anemia, thrombocytopenia, agranulocytosis, and hives.

“Popular FACTSSS”

25
Q

Things that end in…

A
  • Triptan: 5-HT1B/1D agonist
  • Operidol: butyrophenone; neuroleptic; haloperidol
  • azine: phenothiazine; neuroleptic, antiemetic; chlorpromazine
  • ipramine: TCA; imipramine
  • triptyline: TCA; amitriptyline
  • etine: SSRI: fluoxetine
  • pril: ACEi vs. -arb: ACE receptor blocker

STEP 1: pharmacology (8 decks)

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