Drug reactions 1 Flashcards
CV: coronary vasospasm
Cocaine
Sumatriptan
Ergot alkaloid
CV: cutaneous flushing
Vanc
Adenosine
Niacine
Ca2+ inhibitor (nicardipine)
“VANC”
CV: dilated cardiomyopathy
Doxorubicin (adriamycin)
Daunorubicin
CV: torsade de pointes
Class III (sotalol) Class IA (quinidine)
Heme: Agranulocytosis
Clozapine carbamazepine colchicine Propylthiouracil (hyperthyoid) Methimazole (hyperthyroid) Dapsone
“Agranulocytosis could certain cause pretty major damage”
Heme: aplastic anemia
Chloramphenicol Benzene NSAIDS Propylthiouracil (hyperthyoid) Methimazole (hyperthyroid)
Heme: direct Coombs-positive hemolytic anemia
Methyldopa
penicillin
Heme: Gray baby syndrome
Chloramphenicol
Heme: hemolysis in G6PD
INH Sulfonamide Primaquine Aspirin Ibuprofen Nitrosurantoin
“Hemolysis IS PAIN”
Heme: megaloblastic anemia
Phenytoin
MTX
Sulfa
“Having a BLAST with PMS”
Respiratory: pulm fibrosis
Bleomycin
Amiodarone
Busulfan
“It is hard to BLAB when you have pulm fibrosis”
GI: acute cholestatic hepatitis, jaundice
Erythromycin
GI: focal to massive hepatic necrosis
Haloathane
Amantia phalloides
Valproic acid
Acetaminophen
“Liver HAVAc”
GI: hepatitis
INH
GI: pseudomemebranous colitis
Clinda
Amp