Drug Overdoses Flashcards
What are the key features of opioid overdose?
- Low heart rate
- Low resp rate
- Pinpoint pupils
What is the treatment for lithium toxicity?
Fluid recusstation
Sever lithium toxicity is seen in blood levels of ______ or more.
3mmol/L
When do you treat lithium toxicity with haemodialysis?
Severe lithium toxicity or when conservative measures have failed
What is the treatment for paracetamol overdose?
N-acetylcysteine
What are the features of a SSRI overdose?
- Tremor
- Drowsiness
- Tachycardia
- Vomiting
- Generalised clonus
- Dilated pupils
- Diaphoresis (excessive sweating)
- Seizures in severe cases
_________ and ___________ overdose can cause cardiac dysrhythmias (wide complex bradycardia and torsade de pointes).
Citalopram and escitalopram
What are the features of lithium toxicity?
- Coarse tremor
- Hyperreflexia
- Acute confusion
- Polyuria
- Seizure
- Coma
What are the features of atypical antipsychotic overdose?
- Sedation
- Tachycardia
- Mild hypotension
- Prolongation of QT interval
- Delirium
What are the features of a severe sodium valproate overdose?
- CNS depression
- Coma
- Multi-organ toxicity
- Metabolic acidosis
- Cerebral oedema
- Hypotension
What does a propanolol overdose cause?
Sodium channel blockade and therefore QRS widening
What do you treat a propanolol overdose with?
Sodium bicarbonate
What are the clinical features of beta blocker overdose?
- Hypotension
- Bradycardia
- AV block
- Bronchospasm
- Hypoglycaemia
- Hyperkalaemia
- Coma
- Seizures
When do you use atropine to treat beta blocker overdose?
If the patient is bradycardic
