Drug of Abuse Flashcards

1
Q

Types of Opiods

A
  • OPIUM
  • HEROIN
  • OXYCODONE
  • MEPERIDINE
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2
Q

Types of SEDATIVE - HYPNOTICS

A
  • BENZODIAZEPINES
  • BARBITURATES
  • ALCOHOL
  • GAMMA HYDROXYBUTYRIC ACID
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3
Q

Types of CANNABINOIDS

A

MARIJUANA

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4
Q

Types of HALLUCINOGENS

A
  • LSD
  • MESCALINE
  • PSILOCYBIN
  • KETAMINE
  • PHENCYCLIDINE
  • SCOPOLAMINE
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5
Q

OTHER DRUGS OF ABUSE

A
  • COCAINE
  • AMPHETAMINES
  • ECSTASY
  • ANABOLIC STEROIDS
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6
Q

Types of STIMULANTS

A
  • NICOTINE
  • CAFFEINE
  • INHALANTS
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7
Q

Types of INHALANTS

A
  • ANESTHETICS
  • INDUSTRIAL SOLVENTS
  • ORGANIC NITRITES
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8
Q

Papaver somniferum

A

Opium

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9
Q

powerful narcotic, painkiller

A

Opium

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10
Q

principal active ingredient is MORPHINE

A

Opium

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11
Q

insomnia, hallucination,
nightmares

A

Opium

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12
Q

histamine release

A

Opium

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13
Q

SC, IV

A

Opium

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14
Q

more pronounced
effects than heroin

A

Opium

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15
Q

Smack, H, ska, junk

A

Heroin

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15
Q

diamorphine

A

HEROIN

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16
Q

an addictive drug as a white or brown powder

A

HEROIN

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16
Q

tends to be used with other drugs

A

HEROIN

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17
Q

fast-acting

A

HEROIN

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17
Q

IV

A

Heroin

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18
Q

T1/2= 3-5 hrs, therefore several doses/ day

A

HEROIN

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19
Q

Withdrawal 5-10 hrs after

A

HEROIN

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20
Q

synthesized from thebaine

A

Oxycodone

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21
Q

derived from codeine

A

Oxycodone

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22
Q

tablet or oral form

A

Oxycodone

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23
Q

increasingly popular

A

Oxycodone

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24
Q

pethidine

A

Meperidine

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25
Q

Demerol

A

Meperidine

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26
Q

serious interaction with MAO’s

A

Meperidine

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27
Q

attempts to illicitly produce this
has resulted in MPTP which can cause parkinsonism

A

Meperidine

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28
Q

MPTP: methyl-phenyl-tetrahydropyridine

A

Meperidine

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29
Q

can be short- to long- acting

A

Sedative - hypnotics

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30
Q

the longer the duration the less the withdrawal

A

Sedative - hypnotics

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31
Q

anxiety, tremors, twitches, vomiting

A

Sedative - hypnotics

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32
Q

rare occurrence of physiologic dependence

A

Benzodiazepines

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33
Q

weight loss, change in perception, paresthesia, headache

A

“Therapeutic Dose Dependence”

Benzodiazepines

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34
Q

Flunitrazepam

A

Benzodiazepines

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35
Q

“Therapeutic Dose Dependence”

A

Benzodiazepines

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36
Q

used for date rape

A

Flunitrazepam

Benzodiazepines

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37
Q

Rohypnol

A

Benzodiazepines

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38
Q

brand name for the drug flunitrazepam

A

Rohypnol

Benzodiazepines

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39
Q

roofies (1mg tab)

A

Rohypnol

Benzodiazepines

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40
Q

anterograde amnesia

A

Flunitrazepam

Benzodiazepines

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41
Q

Schedule IV

A

Flunitrazepam

Benzodiazepines

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42
Q

anterograde amnesia

A

Flunitrazepam

Benzodiazepines

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43
Q

GABAa receptors

A

Barbiturates

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44
Q

usually Short- acting drugs

A

Barbiturates

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45
Q

eg. Secobarbital, pentobarbital Na

A

Barbiturates

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46
Q

not used as much as other drugs

A

Barbiturates

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47
Q

euphoria

A
  • Alcohol
  • LSD
  • Gamma Hydroxybutyric Acid
  • Marijuana
  • Anesthetics
  • Industrial solvents
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48
Q

Alcoholism

A

Alcohol

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49
Q

Affect GABAa and NMDA

A

Alcohol

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50
Q

withdrawal: motor agitation, anxiety, insomnia, hallucination, abnormal vital signs, seizures

A

Alcohol

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51
Q

GABAb

A

Gamma Hydroxybutyric Acid

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52
Q

naturally found in body

A

Gamma Hydroxybutyric Acid

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53
Q

can be found in fermented drinks like guava
(Psidium guajava)

A

Gamma Hydroxybutyric Acid

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54
Q

euphoric, sedative, anabolic

A

Gamma Hydroxybutyric Acid

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55
Q

widely sold until 1992

A

Gamma Hydroxybutyric Acid

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56
Q

liquid ecstasy, soap, easy lay, vita-G

A

Gamma Hydroxybutyric Acid

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57
Q

Georgia homeboy

A

Gamma Hydroxybutyric Acid

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58
Q

use with alcohol can produce breathing
problems

A

Gamma Hydroxybutyric Acid

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59
Q

withdrawal effects include: insomnia, anxiety, tremors, sweating

A

Gamma Hydroxybutyric Acid

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60
Q

Treatment for Short acting and Long acting drugs:

A

chlordiazepoxide or phenobarbital

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61
Q

Treatment for alcohol

A

disulfiram, naltrexone

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62
Q

Cannabis sativa

A

Marijuana

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63
Q

cannabinol, tetrahydrocannabinol, cannabidiol

A

Marijuana

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64
Q

cannabinoid receptors (CB1)

A

Marijuana

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65
Q

smoked

A

Marijuana

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66
Q

effects in 2-3 inhalations

A

Marijuana

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67
Q

“high,” euphoria, laughter, relaxation

A

Marijuana

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68
Q

Schedule I

A

Marijuana

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69
Q

antiemetic

A

Marijuana

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70
Q

tolerance

A

Marijuana

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71
Q

uncertain effect on fetus

A

Marijuana

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72
Q

Amotivational syndrome

A

Marijuana

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73
Q

diseases related to smoking

A

Marijuana

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74
Q

Dronabinol

A

Marijuana

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75
Q

Chemotheraphy Px

A

Nabilone

Marijuana

76
Q

Mutiple Sclerosis

A

Nabiximol

Marijuana

77
Q

Lysergic acid diethylamide

A

LSD

78
Q

Claviceps purpurea

A

LSD

79
Q

synthetic agent related to ergot alkaloids

A

LSD

80
Q

NE, dopamine, serotonin

A

LSD

81
Q

5-HT1a & 5-HT1c agonists

A

LSD

82
Q

one of the most potent drugs 1ug/kg

A

LSD

83
Q

absence of known fatalities

A

LSD

84
Q

duration based on dose

A

LSD

85
Q

waxing and waning effects

A

LSD

86
Q

rise in body temp

A

LSD

87
Q

uterine contractions

A

LSD

88
Q

elevated sugar levels

A

LSD

89
Q

goosebumps

A

LSD

90
Q

pupil dilation

A

LSD

91
Q

Lophophora williamsii

A

Mescaline

92
Q

restricted but allowed
occasionally to North American Indians

A

Mescaline

93
Q

5-6mg/kg

A

Mescaline

94
Q

Psilocybe mushroom

A

Psilocybin

95
Q

250ug/kg

A

Psilocybin

96
Q

mydriasis, muscle relaxation, dizziness

A

Psilocybin

97
Q

anesthetic

A

Ketamine

98
Q

“special K” “vitamin K”

A

Ketamine

99
Q

dream-like states

A

Ketamine

100
Q

hallucination

A
  • Ketamine
  • LSD
  • Opium
  • Alcohol
  • Inhalants
101
Q

delirium

A

Ketamine

102
Q

amnesia

A

Ketamine

103
Q

high BP

A

Ketamine

104
Q

depression

A

Ketamine

105
Q

fatal respiratory
problems

A

Ketamine

106
Q

angel dust, PCP

A

Phencyclidine

107
Q

phenylcyclohexamine deriv

A

Phencyclidine

108
Q

veterinary anesthetic

A

Phencyclidine

109
Q

smoked with tobacco, snorted, Oral, IV

A

Phencyclidine

110
Q

antagonize NMDA

A

Phencyclidine

111
Q

animals will self administer it

A

Phencyclidine

112
Q

Olney’s lesions

A

Phencyclidine

113
Q

long t1/2

A

Phencyclidine

114
Q

users tend to be violent
and suicidal

A

Phencyclidine

115
Q

“bad-trips”

A

Phencyclidine

116
Q

Hyoscyamus niger

A

Scopolamine

117
Q

block central muscarinic receptors

A

Scopolamine

118
Q

unpleasant to users

A

Scopolamine

119
Q

same effects as other hallucinogens

A

Scopolamine

120
Q

Erythroxylon coca

A

Coccaine

121
Q

dopaminergic reuptake
transmitter

A

Coccaine

122
Q

inhibit reuptake of
dopamine and NE

A

Coccaine

123
Q

free base is absorbed
as fast as IV

A

Coccaine

124
Q

t1/2= 1hr, repeated
30min

A

Coccaine

125
Q

symptoms include a
feeling of bugs
under skin

A

Coccaine

126
Q

paranoia and
schizophrenia like state

A

Coccaine

127
Q

exhaustion by lack of
sleep and food

A

Coccaine

128
Q

appetite, exhaustion,
depression

A

Coccaine

129
Q

alpha-methyl-phenethylamine

A

Amphetamines

130
Q

increase catecholinergic neurotransmitters

A

Amphetamines

131
Q

dopamine not be metabolized thus released

A

Amphetamines

132
Q

treat narcolepsy and ADHD

A

Amphetamines

133
Q

paranoid psychosis

A

Amphetamines

134
Q

necrotizing arteritis

A

Amphetamines

135
Q

OD is rarely fatal

A

Amphetamines

136
Q

managed by benzodiazepines

A

Amphetamines

137
Q

Schedule II

A

Amphetamines

138
Q

decreased appetite, inc. stamina, energy
sexual drive

A

Amphetamines

139
Q

loss of REM sleep, tremor, restlessness,
anxiety,

A

Amphetamines

140
Q

related drugs (shabu, ecstasy)

A

Amphetamines

141
Q

Methylene-dioxymethamphetamine (MDMA)

A

Ecstacy

142
Q

intimacy and empathy

A

Ecstacy

143
Q

“raves” designer drug

A

Ecstacy

144
Q

SERT

A

Ecstacy

145
Q

“uppers,”

A

Stimulants

146
Q

reverse the effects of fatigue on both mental and
physical tasks.

A

Stimulants

147
Q

coffee, tea, some soft drinks, and many
non-prescription medicines

A

Caffeine

148
Q

tobacco products

A

Nicotine

149
Q

Nicotiana tobacum

A

Nicotine

150
Q

nicotinic cholinergic receptor agonist

A

Nicotine

151
Q

1 drop is fatal

A

Nicotine

152
Q

strong psychological and physiological dependence (more addictive than heroin and cocaine)

A

Nicotine

153
Q

Including dopamine

A

Nicotine

154
Q

SIDS, carcinogenic

A

Nicotine

155
Q

1,3,7-trimethylxanthine

A

Caffeine

156
Q

xanthine alkaloid from Coffea arabica

A

Caffeine

157
Q

adenosine receptors

A

Caffeine

158
Q

low chance of abuse and addiction

A

Caffeine

159
Q

5 cups/ day

A

Caffeine

160
Q

anesthetic gases

A

Inhalants

161
Q

industrial solvents

A

Inhalants

162
Q

Inhalants

aerosol propellants

A

Inhalants

163
Q

organic nitrites

A

Inhalants

164
Q

psychoactive effects

A

Inhalants

165
Q

alcohol-like intoxications,
hallucinations,

A

Inhalants

166
Q

hypoxia, pneumonia,
cardiac fauilure

A

Inhalants

167
Q

headache, nausea, vomiting, slurred speech, loss of motor coordination, wheezing

A

Inhalants

168
Q

difficulty in concentrating, dreaminess,
euphoria, numbness, tingling

A

Anesthetics

169
Q

N2O= 35% used; 100% death

A

Anesthetics

170
Q

ether & chloroform

A

Anesthetics

171
Q

gasoline, toluene,
benzene, trichloro-ethylene

A

Industrial solvents

172
Q

5-15min

A

Industrial solvents

173
Q

euphoria, “drunk” feeling,
disorientation

A

Industrial solvents

174
Q

slow passage of time

A

Industrial solvents

175
Q

Eg. Glue, correction fluid,
gas

A

Industrial solvents

176
Q

amyl nitrite, isobutyl nitrite

A

Organic nitrites

177
Q

dizziness, rapid heart rate, lowered BP,
“speeding,” flushing of skin

A

Organic nitrites

178
Q

enhance, prolong erection

A

Organic nitrites

179
Q

Liver, kidney, peripheral nerve, and brain
damage

A

Organic nitrites

180
Q

Bone marrow suspension

A

Organic nitrites

181
Q

Pulmonary disease

A

Organic nitrites

182
Q

Death

A

Organic nitrites

183
Q

cyclopentanoperhydrophenanthrene ring

A

Anabolic Steroids

184
Q

bone growth, appetite, puberty, muscle
growth

A

Anabolic Steroids

185
Q

Schedule III

A

Anabolic Steroids

186
Q

change in libido, irritability, violence, mood
swings, forgetfulness, confusion

A

Anabolic Steroids

187
Q

fatigue, depressed mood, craving for steroids

A

Anabolic Steroids

188
Q

hypertrophied muscles,
acne, oily skin, hirsutism in females, gynecomastia in
males, needle punctures

A

Anabolic Steroids

189
Q

high LDL; low HDL

A

Anabolic Steroids

190
Q

elevated liver function

A

Anabolic Steroids