Drug of Abuse Flashcards
1
Q
Types of Opiods
A
- OPIUM
- HEROIN
- OXYCODONE
- MEPERIDINE
2
Q
Types of SEDATIVE - HYPNOTICS
A
- BENZODIAZEPINES
- BARBITURATES
- ALCOHOL
- GAMMA HYDROXYBUTYRIC ACID
3
Q
Types of CANNABINOIDS
A
MARIJUANA
4
Q
Types of HALLUCINOGENS
A
- LSD
- MESCALINE
- PSILOCYBIN
- KETAMINE
- PHENCYCLIDINE
- SCOPOLAMINE
5
Q
OTHER DRUGS OF ABUSE
A
- COCAINE
- AMPHETAMINES
- ECSTASY
- ANABOLIC STEROIDS
6
Q
Types of STIMULANTS
A
- NICOTINE
- CAFFEINE
- INHALANTS
7
Q
Types of INHALANTS
A
- ANESTHETICS
- INDUSTRIAL SOLVENTS
- ORGANIC NITRITES
8
Q
Papaver somniferum
A
Opium
9
Q
powerful narcotic, painkiller
A
Opium
10
Q
principal active ingredient is MORPHINE
A
Opium
11
Q
insomnia, hallucination,
nightmares
A
Opium
12
Q
histamine release
A
Opium
13
Q
SC, IV
A
Opium
14
Q
more pronounced
effects than heroin
A
Opium
15
Q
Smack, H, ska, junk
A
Heroin
15
Q
diamorphine
A
HEROIN
16
Q
an addictive drug as a white or brown powder
A
HEROIN
16
Q
tends to be used with other drugs
A
HEROIN
17
Q
fast-acting
A
HEROIN
17
Q
IV
A
Heroin
18
Q
T1/2= 3-5 hrs, therefore several doses/ day
A
HEROIN
19
Q
Withdrawal 5-10 hrs after
A
HEROIN
20
Q
synthesized from thebaine
A
Oxycodone
21
Q
derived from codeine
A
Oxycodone
22
tablet or oral form
Oxycodone
23
increasingly popular
Oxycodone
24
pethidine
Meperidine
25
Demerol
Meperidine
26
serious interaction with MAO’s
Meperidine
27
attempts to illicitly produce this
has resulted in MPTP which can cause parkinsonism
Meperidine
28
MPTP: methyl-phenyl-tetrahydropyridine
Meperidine
29
can be short- to long- acting
Sedative - hypnotics
30
the longer the duration the less the withdrawal
Sedative - hypnotics
31
anxiety, tremors, twitches, vomiting
Sedative - hypnotics
32
rare occurrence of physiologic dependence
Benzodiazepines
33
weight loss, change in perception, paresthesia, headache
“Therapeutic Dose Dependence”
| Benzodiazepines
34
Flunitrazepam
Benzodiazepines
35
“Therapeutic Dose Dependence”
Benzodiazepines
36
used for date rape
Flunitrazepam
| Benzodiazepines
37
Rohypnol
Benzodiazepines
38
brand name for the drug flunitrazepam
Rohypnol
| Benzodiazepines
39
roofies (1mg tab)
Rohypnol
| Benzodiazepines
40
anterograde amnesia
Flunitrazepam
| Benzodiazepines
41
Schedule IV
Flunitrazepam
| Benzodiazepines
42
anterograde amnesia
Flunitrazepam
| Benzodiazepines
43
GABAa receptors
Barbiturates
44
usually Short- acting drugs
Barbiturates
45
eg. Secobarbital, pentobarbital Na
Barbiturates
46
not used as much as other drugs
Barbiturates
47
euphoria
- Alcohol
- LSD
- Gamma Hydroxybutyric Acid
- Marijuana
- Anesthetics
- Industrial solvents
48
Alcoholism
Alcohol
49
Affect GABAa and NMDA
Alcohol
50
withdrawal: motor agitation, anxiety, insomnia, hallucination, abnormal vital signs, seizures
Alcohol
51
GABAb
Gamma Hydroxybutyric Acid
52
naturally found in body
Gamma Hydroxybutyric Acid
53
can be found in fermented drinks like guava
(Psidium guajava)
Gamma Hydroxybutyric Acid
54
euphoric, sedative, anabolic
Gamma Hydroxybutyric Acid
55
widely sold until 1992
Gamma Hydroxybutyric Acid
56
liquid ecstasy, soap, easy lay, vita-G
Gamma Hydroxybutyric Acid
57
Georgia homeboy
Gamma Hydroxybutyric Acid
58
use with alcohol can produce breathing
problems
Gamma Hydroxybutyric Acid
59
withdrawal effects include: insomnia, anxiety, tremors, sweating
Gamma Hydroxybutyric Acid
60
Treatment for Short acting and Long acting drugs:
chlordiazepoxide or phenobarbital
61
Treatment for alcohol
disulfiram, naltrexone
62
Cannabis sativa
Marijuana
63
cannabinol, tetrahydrocannabinol, cannabidiol
Marijuana
64
cannabinoid receptors (CB1)
Marijuana
65
smoked
Marijuana
66
effects in 2-3 inhalations
Marijuana
67
“high,” euphoria, laughter, relaxation
Marijuana
68
Schedule I
Marijuana
69
antiemetic
Marijuana
70
tolerance
Marijuana
71
uncertain effect on fetus
Marijuana
72
Amotivational syndrome
Marijuana
73
diseases related to smoking
Marijuana
74
Dronabinol
Marijuana
75
Chemotheraphy Px
Nabilone
| Marijuana
76
Mutiple Sclerosis
Nabiximol
| Marijuana
77
Lysergic acid diethylamide
LSD
78
Claviceps purpurea
LSD
79
synthetic agent related to ergot alkaloids
LSD
80
NE, dopamine, serotonin
LSD
81
5-HT1a & 5-HT1c agonists
LSD
82
one of the most potent drugs 1ug/kg
LSD
83
absence of known fatalities
LSD
84
duration based on dose
LSD
85
waxing and waning effects
LSD
86
rise in body temp
LSD
87
uterine contractions
LSD
88
elevated sugar levels
LSD
89
goosebumps
LSD
90
pupil dilation
LSD
91
Lophophora williamsii
Mescaline
92
restricted but allowed
occasionally to North American Indians
Mescaline
93
5-6mg/kg
Mescaline
94
Psilocybe mushroom
Psilocybin
95
250ug/kg
Psilocybin
96
mydriasis, muscle relaxation, dizziness
Psilocybin
97
anesthetic
Ketamine
98
“special K” “vitamin K”
Ketamine
99
dream-like states
Ketamine
100
hallucination
- Ketamine
- LSD
- Opium
- Alcohol
- Inhalants
101
delirium
Ketamine
102
amnesia
Ketamine
103
high BP
Ketamine
104
depression
Ketamine
105
fatal respiratory
problems
Ketamine
106
angel dust, PCP
Phencyclidine
107
phenylcyclohexamine deriv
Phencyclidine
108
veterinary anesthetic
Phencyclidine
109
smoked with tobacco, snorted, Oral, IV
Phencyclidine
110
antagonize NMDA
Phencyclidine
111
animals will self administer it
Phencyclidine
112
Olney’s lesions
Phencyclidine
113
long t1/2
Phencyclidine
114
users tend to be violent
and suicidal
Phencyclidine
115
“bad-trips”
Phencyclidine
116
Hyoscyamus niger
Scopolamine
117
block central muscarinic receptors
Scopolamine
118
unpleasant to users
Scopolamine
119
same effects as other hallucinogens
Scopolamine
120
Erythroxylon coca
Coccaine
121
dopaminergic reuptake
transmitter
Coccaine
122
inhibit reuptake of
dopamine and NE
Coccaine
123
free base is absorbed
as fast as IV
Coccaine
124
t1/2= 1hr, repeated
30min
Coccaine
125
symptoms include a
feeling of bugs
under skin
Coccaine
126
paranoia and
schizophrenia like state
Coccaine
127
exhaustion by lack of
sleep and food
Coccaine
128
appetite, exhaustion,
depression
Coccaine
129
alpha-methyl-phenethylamine
Amphetamines
130
increase catecholinergic neurotransmitters
Amphetamines
131
dopamine not be metabolized thus released
Amphetamines
132
treat narcolepsy and ADHD
Amphetamines
133
paranoid psychosis
Amphetamines
134
necrotizing arteritis
Amphetamines
135
OD is rarely fatal
Amphetamines
136
managed by benzodiazepines
Amphetamines
137
Schedule II
Amphetamines
138
decreased appetite, inc. stamina, energy
sexual drive
Amphetamines
139
loss of REM sleep, tremor, restlessness,
anxiety,
Amphetamines
140
related drugs (shabu, ecstasy)
Amphetamines
141
Methylene-dioxymethamphetamine (MDMA)
Ecstacy
142
intimacy and empathy
Ecstacy
143
“raves” designer drug
Ecstacy
144
SERT
Ecstacy
145
“uppers,”
Stimulants
146
reverse the effects of fatigue on both mental and
physical tasks.
Stimulants
147
coffee, tea, some soft drinks, and many
non-prescription medicines
Caffeine
148
tobacco products
Nicotine
149
Nicotiana tobacum
Nicotine
150
nicotinic cholinergic receptor agonist
Nicotine
151
1 drop is fatal
Nicotine
152
strong psychological and physiological dependence (more addictive than heroin and cocaine)
Nicotine
153
Including dopamine
Nicotine
154
SIDS, carcinogenic
Nicotine
155
1,3,7-trimethylxanthine
Caffeine
156
xanthine alkaloid from Coffea arabica
Caffeine
157
adenosine receptors
Caffeine
158
low chance of abuse and addiction
Caffeine
159
5 cups/ day
Caffeine
160
anesthetic gases
Inhalants
161
industrial solvents
Inhalants
162
# Inhalants
aerosol propellants
Inhalants
163
organic nitrites
Inhalants
164
psychoactive effects
Inhalants
165
alcohol-like intoxications,
hallucinations,
Inhalants
166
hypoxia, pneumonia,
cardiac fauilure
Inhalants
167
headache, nausea, vomiting, slurred speech, loss of motor coordination, wheezing
Inhalants
168
difficulty in concentrating, dreaminess,
euphoria, numbness, tingling
Anesthetics
169
N2O= 35% used; 100% death
Anesthetics
170
ether & chloroform
Anesthetics
171
gasoline, toluene,
benzene, trichloro-ethylene
Industrial solvents
172
5-15min
Industrial solvents
173
euphoria, “drunk” feeling,
disorientation
Industrial solvents
174
slow passage of time
Industrial solvents
175
Eg. Glue, correction fluid,
gas
Industrial solvents
176
amyl nitrite, isobutyl nitrite
Organic nitrites
177
dizziness, rapid heart rate, lowered BP,
“speeding,” flushing of skin
Organic nitrites
178
enhance, prolong erection
Organic nitrites
179
Liver, kidney, peripheral nerve, and brain
damage
Organic nitrites
180
Bone marrow suspension
Organic nitrites
181
Pulmonary disease
Organic nitrites
182
Death
Organic nitrites
183
cyclopentanoperhydrophenanthrene ring
Anabolic Steroids
184
bone growth, appetite, puberty, muscle
growth
Anabolic Steroids
185
Schedule III
Anabolic Steroids
186
change in libido, irritability, violence, mood
swings, forgetfulness, confusion
Anabolic Steroids
187
fatigue, depressed mood, craving for steroids
Anabolic Steroids
188
hypertrophied muscles,
acne, oily skin, hirsutism in females, gynecomastia in
males, needle punctures
Anabolic Steroids
189
high LDL; low HDL
Anabolic Steroids
190
elevated liver function
Anabolic Steroids
