Drug of Abuse Flashcards
Types of Opiods
- OPIUM
- HEROIN
- OXYCODONE
- MEPERIDINE
Types of SEDATIVE - HYPNOTICS
- BENZODIAZEPINES
- BARBITURATES
- ALCOHOL
- GAMMA HYDROXYBUTYRIC ACID
Types of CANNABINOIDS
MARIJUANA
Types of HALLUCINOGENS
- LSD
- MESCALINE
- PSILOCYBIN
- KETAMINE
- PHENCYCLIDINE
- SCOPOLAMINE
OTHER DRUGS OF ABUSE
- COCAINE
- AMPHETAMINES
- ECSTASY
- ANABOLIC STEROIDS
Types of STIMULANTS
- NICOTINE
- CAFFEINE
- INHALANTS
Types of INHALANTS
- ANESTHETICS
- INDUSTRIAL SOLVENTS
- ORGANIC NITRITES
Papaver somniferum
Opium
powerful narcotic, painkiller
Opium
principal active ingredient is MORPHINE
Opium
insomnia, hallucination,
nightmares
Opium
histamine release
Opium
SC, IV
Opium
more pronounced
effects than heroin
Opium
Smack, H, ska, junk
Heroin
diamorphine
HEROIN
an addictive drug as a white or brown powder
HEROIN
tends to be used with other drugs
HEROIN
fast-acting
HEROIN
IV
Heroin
T1/2= 3-5 hrs, therefore several doses/ day
HEROIN
Withdrawal 5-10 hrs after
HEROIN
synthesized from thebaine
Oxycodone
derived from codeine
Oxycodone
tablet or oral form
Oxycodone
increasingly popular
Oxycodone
pethidine
Meperidine
Demerol
Meperidine
serious interaction with MAO’s
Meperidine
attempts to illicitly produce this
has resulted in MPTP which can cause parkinsonism
Meperidine
MPTP: methyl-phenyl-tetrahydropyridine
Meperidine
can be short- to long- acting
Sedative - hypnotics
the longer the duration the less the withdrawal
Sedative - hypnotics
anxiety, tremors, twitches, vomiting
Sedative - hypnotics
rare occurrence of physiologic dependence
Benzodiazepines
weight loss, change in perception, paresthesia, headache
“Therapeutic Dose Dependence”
Benzodiazepines
Flunitrazepam
Benzodiazepines
“Therapeutic Dose Dependence”
Benzodiazepines
used for date rape
Flunitrazepam
Benzodiazepines
Rohypnol
Benzodiazepines
brand name for the drug flunitrazepam
Rohypnol
Benzodiazepines
roofies (1mg tab)
Rohypnol
Benzodiazepines
anterograde amnesia
Flunitrazepam
Benzodiazepines
Schedule IV
Flunitrazepam
Benzodiazepines
anterograde amnesia
Flunitrazepam
Benzodiazepines
GABAa receptors
Barbiturates
usually Short- acting drugs
Barbiturates
eg. Secobarbital, pentobarbital Na
Barbiturates
not used as much as other drugs
Barbiturates
euphoria
- Alcohol
- LSD
- Gamma Hydroxybutyric Acid
- Marijuana
- Anesthetics
- Industrial solvents
Alcoholism
Alcohol
Affect GABAa and NMDA
Alcohol
withdrawal: motor agitation, anxiety, insomnia, hallucination, abnormal vital signs, seizures
Alcohol
GABAb
Gamma Hydroxybutyric Acid
naturally found in body
Gamma Hydroxybutyric Acid
can be found in fermented drinks like guava
(Psidium guajava)
Gamma Hydroxybutyric Acid
euphoric, sedative, anabolic
Gamma Hydroxybutyric Acid
widely sold until 1992
Gamma Hydroxybutyric Acid
liquid ecstasy, soap, easy lay, vita-G
Gamma Hydroxybutyric Acid
Georgia homeboy
Gamma Hydroxybutyric Acid
use with alcohol can produce breathing
problems
Gamma Hydroxybutyric Acid
withdrawal effects include: insomnia, anxiety, tremors, sweating
Gamma Hydroxybutyric Acid
Treatment for Short acting and Long acting drugs:
chlordiazepoxide or phenobarbital
Treatment for alcohol
disulfiram, naltrexone
Cannabis sativa
Marijuana
cannabinol, tetrahydrocannabinol, cannabidiol
Marijuana
cannabinoid receptors (CB1)
Marijuana
smoked
Marijuana
effects in 2-3 inhalations
Marijuana
“high,” euphoria, laughter, relaxation
Marijuana
Schedule I
Marijuana
antiemetic
Marijuana
tolerance
Marijuana
uncertain effect on fetus
Marijuana
Amotivational syndrome
Marijuana
diseases related to smoking
Marijuana
Dronabinol
Marijuana