Drug Interactions and Reactions Flashcards
P-450 Inducers
Queen Barb Steals Phen-phen and Refuses Greasy Carbs
Quinidine, Barbiturates, St. Johns Wort, Phenytoin, Rifampin, Griseofulvin, Carbamazepine
P-450 inhibitors
Cimetidine, ketoconazole, INH, grapefruit, erythromycin, sulfonamides
Metabolized by P-450
Benzos, amide anesthetics, metop, propranolol, nifedipine, phenytoin, quinidine, theophylline, warfarin, barbiturates
Increases the risk of digoxin toxicity
quinidine
cimetidine
amiodarone
CCBs
Bloody dyscrasias
ibuprofen
quinidine
methyldopa
chemo
Hemolysis in G6PD deficiency
sulfonamides, INH, ASA, ibuprofen, nitrofurantoin, primaquine, pyrimethamine, chloramphenicol
Gynecomastia inducing drugs
Some Excellent Drugs Create Awesome Knockers
Spironolactone, Estrogens, Digitalis, CImetidine, chronic Alcohol use, Ketoconazole
Stevens Johnson
anticonvulsants, sulfas, PCN
Photosensitivity
tetracycline, doxycycline amiodarone, sulfa
Drug-induced SLE
Procainamide, hydralazine, INH, penicillamine, chlorpromazine, methyldopa, quinidine