Drug interactions Flashcards
1
Q
Increased risk of QT interval prolongations
A
Amiodarone (anti-arrhythmics)
Ciprofloxacin (quinolones)
Macrolides
Quinine
SSRIs
2
Q
Increased risk of EPS
A
Metoclopramide (dopamine agonist)
PD (levodopa)
3
Q
Increased risk of sedation & CNS depressant effects
A
Hypnotics (e.g. zopiclone(
BDZ
Opioids
Antiepileptics
Alcohol
4
Q
Increased risk of hypotension
A
Anti-hypertensives (e.g. beta-blockers, CCBs)
Diuretics
Nitrates
5
Q
Increased risk of antimuscarinic effects
A
TCAs
Antihistamines
Antimuscarinics (e.g. hyoscine)