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Ama - Psychoses and Schizophrenia > 2nd generation antipsychotics (ATYPICAL) > Flashcards

2nd generation antipsychotics (ATYPICAL) Flashcards

1
Q

MoA

A

Blocks post-synaptic dopamine (D1-D4) receptors.
Acts on a wide range of other receptors = distinct clinical side effects.

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2
Q

General facts for atypical antipsychotics

A

More metabolic side effects
May be more effective at treating negative symptoms

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3
Q
A
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4
Q

Other antipsychotics

A

Amisulpride
Aripiprazole
Lurasidone
Paliperidone

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5
Q

Amisulpride

A

Most hyperprolactinaemia

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6
Q

Aripiprazole

A

DOESN’T cause hyperprolactinaemia

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7
Q

Clozapine

A

Agranulocytosis
Myocarditis
GI obstruction
Most weight gain + diabetes

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8
Q

Olanzapine

A

Most weight gain + diabetes

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9
Q

Risperidone

A

Most hyperprolactinaemia

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10
Q

Commonly used antipsychotics

A

Quetiapine
Olanzapine
Risperidone
Clozapine

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Ama - Psychoses and Schizophrenia (11 decks)

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