Drug - fill in blanks Flashcards
1
Q
A
- Tgfß
- Cytokine
- RTK
- GPCR
- Wingless
- Hedgehog
- TNF(alpha)
- Notch
2
Q
A
- Atropine
- Muscarine
- M1
- M3
- M5
- M2
- M4
- Gq(alpha)
- PLC
- Ca2+
- AC
- Gi(alpha)
- Gi(beta)(gamma)
- K+ channel
- cAMP
- HCN channel
3
Q
A
- Adenosine
- Caffeine
- A1
- A2A
- A2B
- A3
- Gq(alpha)
- Gi(alpha)
- cAMP
- cAMP
- Gs(alpha)
- Gi(beta)(gamme)
- Gi(alpha)
- cAMP
4
Q
A
- Alpha tubulin
- Beta tubulin
- Vinca binding site
- Taxane binding site
- Cochicine binding site
5
Q
A
- Vinblastine
- Cochicine, combrestatin
- Taxol
- Tubulin-cochicine complex
- Paclitaxel
6
Q
A
- Plant derived ligands (THC, CBD)
- 2-AG
- AEA
- PLC(beta)
- Gq/11
- GABA or Glutamate
- MAPK
- CB1
- AC
- Ca2+
- K+
7
Q

A
- Binding of hormone induces conformational change in receptor
- Activated receptor binds to G(alpha) subunit
- Activated receptor causes conformational changes in G(alpha)’ triggering dissociation of GDP
- Binding of GTP to G(alpha) triggers dissociation of G(alpha) both from the receptor and from G(beta)(gamma)
- Hormone dissociates from receptor, G(alpha) binds to effector, activating it
- Hydrolysis of GTP to GDP causes G(alpha) to dissociate from effector and reassociate with G(beta)(Gamma)

8
Q
A
- Gs/i(alpha)
- AC
- cAMP
- PKA
- Phosphorylation of Enzymes or CREB
- Golf
- Gq
- PLC
- DAG
- IP3
- ER
- Ca2+
- cAMP pathway
- Phospholipid pathway
9
Q

A
- Voltage gated
- Ligand gated (extracellular ligand)
- Ligand gated (intracellular ligand)
- Mechanically gated

10
Q
A
- MEP
- IPP
- DMAPP
- GPP
- Monoterpenes
- Caratenoids
- Diterpenes
- MVA
- IPP
- DMAPP
- FPP
- sesquiterpenes
- Triterpenes
11
Q
A
- Actin
- Myosin
- Actin
- Myosin
- Actin
- Z-Disk
- Z-disk
- ATP, Ca2+
12
Q
A
- Ca2+
- Ca2+
- Acetylcholine
- Voltage gated Na+ channel
- Voltage gated Ca2+ channel
- Sarcoplasmic reticulum (SR)
- Nicotinergic acetylcholine receptor
- Ca2+ gated Ca2+ release channel
- Action potential
- not actually something here
- Na+
- Ca2+
- Na+
- Ca2+
13
Q
A
- Prophase
- Metaphase
- anaphase
- telophase and cytokinesis
- APC/C
- APC/C and Cdc14
- Drugs interfering with growth factor signaling
- DNA damaging drugs, Topoisomerase-inhibition
- Drugs inhibiting Cdc25
- Drugs binding tubulin
14
Q
A
- Primary carbon metabolism
- Tricarboxylic acid cycle
- Shikimic acid cycle
- Malonic acid pathway
- Mevalonic acid pathway
- MEP pathway
- Nitrogen containing secondary products
- Phenolic compounds
- terpenes
- Secondary carbon metabolism
15
Q

A
- Phenylalanine
- Tyrosine
- Tyramine
- Phenylpropanoid pathway
- Lignans
- Flavanoids
- Acetyl CoA
- Cytoplasmid MVA pathway
- Sesquiterpenes
- Triterpenes
- Pyruvate
- Plastid MEP pathway
- Monoterpenes
- Fatty acid
- Polyketide pathway
- Cannabinoids

16
Q
A
- Ca2+
- Sarcolemma
- Mitochondria
- Myofibrils
- Nucleus
- T-Tubule
- Sarcoplasmic reticulum
- Skeletal Muscle fiber
17
Q
A
- Survival factors
- Survival factor receptors
- PDK
- PI 3-kinase
- Wortmannin
- PKB/Akt
- Survival
- Metabolism
18
Q
A
- Sympathetic
- Parasympathetic
- Short
- Long
- long
- Short
- Acetylcholine
- Muscarinic receptor
- Adrenergic receptor
19
Q
A
- Acetylcholine
- Inhibitory interneuorn, Renshaw cell
- Acetylcholine
- Botulinus
- (alpha)-motor neuron
- Excitatory collateral
- Tetanus
- Glycine
20
Q
A
- Ca2+
- VAMP (V-SNARE)
- Membrane of synaptic vesicle
- Rab 3A
- Synaptotagmin
- Ca2+ ions
- SNAP25
- Ca2+ channel
- Neurexin
- Plasma membrane of axon terminus
- Syntaxin (T-SNARE)
21
Q
A
- VOCa2+
- Ca2+
- Membrane depolarized
- Membrane hyperpolarized
- Ca2+ sparklet
- sparklet diffuses
- Closed
- open
- Inactive
- Closed
- Recovery from inactivation
- Activation
- Deactivation/Inactivation
22
Q
A
- Gate
- Channel-inactivating segment
- Voltage sensing (alpha) helix
- Ion-selective pore
- Outer vestibule
- Inner vestibule
- Na+
- Na+
- Depolarized membrane
- Refractory period