Drug - fill in blanks Flashcards

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1
Q
A
  1. Tgfß
  2. Cytokine
  3. RTK
  4. GPCR
  5. Wingless
  6. Hedgehog
  7. TNF(alpha)
  8. Notch
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2
Q
A
  1. Atropine
  2. Muscarine
  3. M1
  4. M3
  5. M5
  6. M2
  7. M4
  8. Gq(alpha)
  9. PLC
  10. Ca2+
  11. AC
  12. Gi(alpha)
  13. Gi(beta)(gamma)
  14. K+ channel
  15. cAMP
  16. HCN channel
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3
Q
A
  1. Adenosine
  2. Caffeine
  3. A1
  4. A2A
  5. A2B
  6. A3
  7. Gq(alpha)
  8. Gi(alpha)
  9. cAMP
  10. cAMP
  11. Gs(alpha)
  12. Gi(beta)(gamme)
  13. Gi(alpha)
  14. cAMP
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4
Q
A
  1. Alpha tubulin
  2. Beta tubulin
  3. Vinca binding site
  4. Taxane binding site
  5. Cochicine binding site
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5
Q
A
  1. Vinblastine
  2. Cochicine, combrestatin
  3. Taxol
  4. Tubulin-cochicine complex
  5. Paclitaxel
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6
Q
A
  1. Plant derived ligands (THC, CBD)
  2. 2-AG
  3. AEA
  4. PLC(beta)
  5. Gq/11
  6. GABA or Glutamate
  7. MAPK
  8. CB1
  9. AC
  10. Ca2+
  11. K+
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7
Q
A
  1. Binding of hormone induces conformational change in receptor
  2. Activated receptor binds to G(alpha) subunit
  3. Activated receptor causes conformational changes in G(alpha)’ triggering dissociation of GDP
  4. Binding of GTP to G(alpha) triggers dissociation of G(alpha) both from the receptor and from G(beta)(gamma)
  5. Hormone dissociates from receptor, G(alpha) binds to effector, activating it
  6. Hydrolysis of GTP to GDP causes G(alpha) to dissociate from effector and reassociate with G(beta)(Gamma)
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8
Q
A
  1. Gs/i(alpha)
  2. AC
  3. cAMP
  4. PKA
  5. Phosphorylation of Enzymes or CREB
  6. Golf
  7. Gq
  8. PLC
  9. DAG
  10. IP3
  11. ER
  12. Ca2+
  13. cAMP pathway
  14. Phospholipid pathway
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9
Q
A
  1. Voltage gated
  2. Ligand gated (extracellular ligand)
  3. Ligand gated (intracellular ligand)
  4. Mechanically gated
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10
Q
A
  1. MEP
  2. IPP
  3. DMAPP
  4. GPP
  5. Monoterpenes
  6. Caratenoids
  7. Diterpenes
  8. MVA
  9. IPP
  10. DMAPP
  11. FPP
  12. sesquiterpenes
  13. Triterpenes
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11
Q
A
  1. Actin
  2. Myosin
  3. Actin
  4. Myosin
  5. Actin
  6. Z-Disk
  7. Z-disk
  8. ATP, Ca2+
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12
Q
A
  1. Ca2+
  2. Ca2+
  3. Acetylcholine
  4. Voltage gated Na+ channel
  5. Voltage gated Ca2+ channel
  6. Sarcoplasmic reticulum (SR)
  7. Nicotinergic acetylcholine receptor
  8. Ca2+ gated Ca2+ release channel
  9. Action potential
  10. not actually something here
  11. Na+
  12. Ca2+
  13. Na+
  14. Ca2+
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13
Q
A
  1. Prophase
  2. Metaphase
  3. anaphase
  4. telophase and cytokinesis
  5. APC/C
  6. APC/C and Cdc14
  7. Drugs interfering with growth factor signaling
  8. DNA damaging drugs, Topoisomerase-inhibition
  9. Drugs inhibiting Cdc25
  10. Drugs binding tubulin
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14
Q
A
  1. Primary carbon metabolism
  2. Tricarboxylic acid cycle
  3. Shikimic acid cycle
  4. Malonic acid pathway
  5. Mevalonic acid pathway
  6. MEP pathway
  7. Nitrogen containing secondary products
  8. Phenolic compounds
  9. terpenes
  10. Secondary carbon metabolism
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15
Q
A
  1. Phenylalanine
  2. Tyrosine
  3. Tyramine
  4. Phenylpropanoid pathway
  5. Lignans
  6. Flavanoids
  7. Acetyl CoA
  8. Cytoplasmid MVA pathway
  9. Sesquiterpenes
  10. Triterpenes
  11. Pyruvate
  12. Plastid MEP pathway
  13. Monoterpenes
  14. Fatty acid
  15. Polyketide pathway
  16. Cannabinoids
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16
Q
A
  1. Ca2+
  2. Sarcolemma
  3. Mitochondria
  4. Myofibrils
  5. Nucleus
  6. T-Tubule
  7. Sarcoplasmic reticulum
  8. Skeletal Muscle fiber
17
Q
A
  1. Survival factors
  2. Survival factor receptors
  3. PDK
  4. PI 3-kinase
  5. Wortmannin
  6. PKB/Akt
  7. Survival
  8. Metabolism
18
Q
A
  1. Sympathetic
  2. Parasympathetic
  3. Short
  4. Long
  5. long
  6. Short
  7. Acetylcholine
  8. Muscarinic receptor
  9. Adrenergic receptor
19
Q
A
  1. Acetylcholine
  2. Inhibitory interneuorn, Renshaw cell
  3. Acetylcholine
  4. Botulinus
  5. (alpha)-motor neuron
  6. Excitatory collateral
  7. Tetanus
  8. Glycine
20
Q
A
  1. Ca2+
  2. VAMP (V-SNARE)
  3. Membrane of synaptic vesicle
  4. Rab 3A
  5. Synaptotagmin
  6. Ca2+ ions
  7. SNAP25
  8. Ca2+ channel
  9. Neurexin
  10. Plasma membrane of axon terminus
  11. Syntaxin (T-SNARE)
21
Q
A
  1. VOCa2+
  2. Ca2+
  3. Membrane depolarized
  4. Membrane hyperpolarized
  5. Ca2+ sparklet
  6. sparklet diffuses
  7. Closed
  8. open
  9. Inactive
  10. Closed
  11. Recovery from inactivation
  12. Activation
  13. Deactivation/Inactivation
22
Q
A
  1. Gate
  2. Channel-inactivating segment
  3. Voltage sensing (alpha) helix
  4. Ion-selective pore
  5. Outer vestibule
  6. Inner vestibule
  7. Na+
  8. Na+
  9. Depolarized membrane
  10. Refractory period