Drug by Use

Question 1

Penicillin G

Answer 1

gram - cocci

Question 2

Penicillin V

Answer 2

gram + rods, anaerobes (but not bacteroides)

Question 3

Penicillinase-resistant

Answer 3

penicillinase MSSA, skin infections

may want to combine with clavulanate

Question 4

Amoxicillin

Answer 4

gram - rods (H. flu, E. coli)

gram + cocci

Question 5

Antipseudomonal

Answer 5

Pseudomonas

Bacteroides + other anaerobes

Question 6

Cephalexin

Answer 6

gram + cocci

gram - rods (proteus, diarrhea E. coli)

Question 7

Ceflacor, Cefuroxime

Answer 7

good gram - rods (H. flu)

Bacteroides

Question 8

Cefdinir Ceftriaxone

Answer 8

expanded gram - rods
good gram + cocci (for ceftriaxone)
some antipseudomonal

Question 9

Vancomycin

Answer 9

narrow spectrum gram + cocci

MRSA, enterococci,C. diff

Question 10

Carbapenems

Answer 10

widespread (reserved for multi-drug-resistant organisms)

Question 11

Azythromycin

Answer 11

extended gram + rods/cocci
some gram - bacilli
atypical: mycoplasma/chlamydia

Question 12

Doxycyclin

Answer 12

broad spectrum (many now resistant)
CA-MRSA
Atypical: chlamydia, mycoplasma

Question 13

Minocycline

Answer 13

broad spectrum (many now resistant)
CA-MRSA
Atypical: chlamydia, mycoplasma

Question 14

Clindamycin

Answer 14

narrow spectrum gram + cocci
anaerobes (not C. diff)
CA-MRSA

Question 15

Aminoglycoside

Answer 15

narrow spectrum gram - aerobes (E.coli, Pseudomonas)

Question 16

Chloramphenicol

Answer 16

broad spectrum gram -/+ cocci

Neisseria (meningitis) H. flu, Rickettsia

Question 17

Oxazolidinones

Answer 17

excellent gram + (staph, strep, entero)

reserve for multi-drug resistant cases

Question 18

Streptogamins

Answer 18

excellent gram +

reserve for multi-drug resistant cases

Question 19

Ciprofloxacin

Answer 19

excellent gram - (Pseudomonas, UTI’s)

Question 20

Levofloxacin

Answer 20

excellent gram -/+ (“respiratory,” UTI’s)

Question 21

Nitrofurantoin

Answer 21

1st line against UTI’s if SMX-TMP resistant E. coli

Question 22

Metronidazole

Answer 22

anaerobic bacteria (C. diff)
protozoa

Question 23

Sulfamethoxazole/Trimethoprim

Answer 23

broad spectrum gram -/+
chlamydia, CA-MRSA
some protozoa, UTI

Question 24

Isoniazid

Answer 24

TB

Question 25

Rifampin

Answer 25

TB and numerous -/+ anaerobes

Question 26

Ethambutol

Answer 26

TB

Question 27

Pyrazinamide

Answer 27

TB

Question 28

Streptomycin

Answer 28

TB

Question 29

Amphoteracin

Answer 29

broad spectrum | choice for life-threatening systemic conditions

Question 30

Nystatin

Answer 30

superficial Candidal Infections

Question 31

Caspofungin

Answer 31

aspergillosis

Question 32

Fluconazole

Answer 32

oropharangeal/esophageal candidiasis | vulvovaginal candidiasis

Question 33

Terbinafine

Answer 33

onychomycosis of finger/toe nails

Question 34

Flucytosine

Answer 34

serious infections of cryptococcosis and candidiasis

Question 35

Griseofulvin

Answer 35

severe dermophytosis of skin, hair, finger/toe nails

Question 36

Acyclovir

Answer 36

HSV-1/HSV-2 [Herpes]

Question 37

Valacyclovir

Answer 37

HSV-1/HSV-2 [Herpes]

Question 38

Entecavir

Answer 38

Hepatitis B (first line Tx)

Question 39

Tenofovir

Answer 39

Hepatitis B (first line TX with other resistance)

Question 40

Interferon-α

Answer 40

Hepatitis B/C

Question 41

Ribavirin

Answer 41

respiratory syncitial virus (RSV) | Hepatitis C

Question 42

Telaprevir, Boceprevir

Answer 42

Hepatitis C

Question 43

Sufosbuvir

Answer 43

Hepatits C

Question 44

Emtricitabine

Answer 44

HIV backbone therapy | also Hepatitis B

Question 45

Tenofovir

Answer 45

HIV backbone therapy | also Hepatitis B

Question 46

Efavirenz

Answer 46

always used in combo HIV therapy

Question 47

Atazanavir

Answer 47

HIV protease inhibitor | base therapy with 2 NRTI's

Question 48

Darunavir

Answer 48

HIV protease inhibitor | base therapy with 2 NRTI's

Question 49

Ritonavir

Answer 49

HIV protease inhibitor | base therapy with 2 NRTI's

Question 50

Raltegravir

Answer 50

HIV protease inhibitor | base therapy with 2 NRTI's

Question 51

Enfuviritide

Answer 51

HIV option w/ multi-drug resistance

Question 52

Maraviroc

Answer 52

HIV option w/ multi-drug resistance