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1
Q
  1. Drugs acting on gastrointestinal and urogenital smooth muscles. Drugs influencing uterine function.
    Histamine and antihistamines (H1-blockers)
A

papaverine
Drotaverine
butylscopolamine
misoprostol
oxytocin
ergotamine
terbutaline
atosiban
Mg++
solifenacin
Oxybutinin
tamsulosin
diphenhydramine
(levo)cetirizine
(des)loratadine
dimetinden
fexofenadin
chloropyramine

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2
Q
  1. Cholinergic transmission and its presynaptic modification.
A

botulinum toxin

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3
Q
  1. Adrenergic transmission and its presynaptic modification
A

levodopa
carbidopa

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4
Q
  1. Cholinomimetics
A

carbachol
pilocarpine
Carbamates
neostigmine
pyridostigmine
rivastigmine

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5
Q
  1. Muscarinic receptor blocking drugs
A

atropine
butylscopolamine
solifenacin
Oxybutinin
ipratropium
Tiotropium
cyclopentolate
procyclidine

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6
Q
  1. Catecholamines
A

epinephrine
norepinephrine
dopamine
isoprenalin
dobutamine

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7
Q
  1. Indirect sympathomimetics. Selective a1 and a2-agonists and drugs acting on the imidazoline receptors
A

ephedrine
methylphenidat
clonidine
rilmenidine
methyldopa
oxymetazoline
phenylephrine

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8
Q
  1. a-receptor antagonists
A

prazosin
doxazosin
tamsulozin
urapidil
carvedilol
phentolamine

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9
Q
  1. B-receptor antagonists
A

propranolol
timolol
sotalol
Esmolol
metoprolol
bisoprolol
nebivolol
Carvedilol

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10
Q
  1. Centrally and peripherally acting skeletal muscle relaxants
A

baclofen
tolperisone
diazepam
tizanidine
Botulinum Toxin
Dantrolene
(cis)atracurium
mivacurium
pipecuronium
rocuronium
succynylcholine

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11
Q
  1. Local anesthetics
A

cocaine
lidocaine
articaine
bupivacaine
benzocaine

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12
Q
  1. Natural opioids, opioid receptors
A

morphine
codeine

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13
Q
  1. Semisynthetic and synthetic opioids
A

hydromorphone
dihydrocodeine
oxycodone
buprenorphine
nalbuphine
Naloxone
Naltrexone
methadone
tramadol
diphenoxylate
loperamide
Fentanyl
Meperidin

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14
Q
  1. General properties of NSAIDs. Acetylsalicylic acid. Drugs used for treatment of gout.
A

acetylsalicylic acid

colchicin
allopurinol
rasburicase

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15
Q
  1. NSAIDs, except acetylsalicylic acid. Non-opioid and adjuvant analgesics. Drugs for headache
    syndromes
A

metamizole
naproxen
ibuprofen
ketoprofen
phenylbutazone
indomethacin
diclofenac
celecoxib
meloxicam
paracetamol
sumatriptan
Valproate
propranolol
cinnarizine
Verapamil
galcanezumab
amitriptyline

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16
Q
  1. Inhalational anesthetics
A

NO
isoflurane
desflurane
sevoflurane

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17
Q
  1. Intravenous anesthetics. Perioperative medication
A

thiopental
propofol
etomidate
Midazolam
ketamine
dexmedetomidine
fentanyl
atropine
antacid drugs
antihistamines
analgesics
metoclopramide

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18
Q
  1. Benzodiazepines
A

alprazolam
diazepam
clonazepam
midazolam
nitrazepam
flumazenil

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19
Q
  1. Non benzodiazepine anxiolytics and non-benzodiazepine hypnotics.
A

zolpidem
zaleplone
melatonin
ramelteon
buspirone
SSRI antidepressants

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20
Q
  1. Antipsychotics
A

haloperidol
droperidol
clozapine
olanzapine
Risperidone
quetiapine
Aripiprazole
tiapride
cariprazine

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21
Q
  1. Tricyclic, tetracyclic and unicyclic antidepressants. MAO-inhibitors
A

clomipramine
Amitryptilline
moclobemide

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22
Q
  1. Selective monoamine reuptake inhibitors.
A

fluoxetine
sertraline
(es)citalopram
duloxetine
venlafaxine
reboxetine

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23
Q
  1. Norepinephrine and serotonin receptor antagonist antidepressants. Agomelatine. Tianeptine. Agents
    used for treatment of manic phase of bipolar disorders.
A

mirtazapine
vortioxetin
agomelatine
tianeptine
Lithium Carbonate

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24
Q
  1. Antiepileptics used in partial seizures and generalized tonic-clonic seizures except for the “broad
    spectrum” agents.
A

Carbamezapine
phenytoin
phenobarbital
pregabalin
gabapentin

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25
Q
  1. Antiepileptics used in absence seizures. “Broad spectrum” antiepileptic drugs. Drugs used for treatment
    of status epilepticus
A

ethosuximide
clonazepam
lamotrigine
Valproate
levetiracetam
diazepam
vigabatrine

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26
Q
  1. Drugs acting in the extrapyramidal motoric system. Nootropic drugs
A

levodopa
carbidopa
entacapone
ropinirole
pramiprexole
selegiline
amantadine
procyclidine
memantine
rivastigmine
piracetam

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27
Q
  1. General considerations of antimicrobial therapy. Disinfectants and antiseptics
A

ethanol
isopropyl alcohol
chlorhexidine
octenidin
H2O2
invert soaps
povidone iodine

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28
Q
  1. Antimycobacterial drugs
A

isoniazid
rifampin
pyrazinamide
ethambutol
streptomycin
kanamycin
cycloserine
dapson

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29
Q
  1. Antiprotozoal and antihelminthic drugs.
A

primaquine
mefloquine
quinine
chloroquine
artemether
Lumefantrine
Proguanil
Atovaquone
metronidazole
mebendazole
ivermectin
niclosamide

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30
Q
  1. Antifungal agents
A

clotrimazole
fluconazole
itraconazole
voriconazole
terbinafine
nystatin
amphothericin B
caspofungin
flucytosine

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31
Q
  1. Agents to treat Herpes simplex (HSV), varicella-zoster (VZV) virus, cytomegalovirus (CMV). Antiinfluenza agents Drugs against Corona- and other viruses
A

(val)aciclovir
(val)ganciclovir
foscarnet
Letermovir
ribavirin
palivizumab
Oseltamivir
remdesivir
molnupiravir
nirmatrelvir

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32
Q
  1. Antiretroviral agents.
A

zidovudine
lamivudine
tenofovir
emtricitabine
abacavir
etravirine
darunavir
ritonavir
dolutegravir
maraviroc

33
Q
  1. Agents against hepatitis viruses
A

interferon-α
entecavir
tenofovir
sofosbuvir
dasabuvir
paritaprevir
grazoprevir
velpatasvir
elbasavir

34
Q
  1. Penicillins
A

penicillin G
benzathin-penicillin
penicillin V
flucloxacillin
amoxicillin
ampicillin
piperacillin

35
Q
  1. Cephalosporins
A

cephalexin
cephazolin
cefuroxime (-axetil)
cefoxitine
cefixime
ceftriaxone
cefotaxime
ceftazidime
Cefepime
Ceftarolin Fosamil
ceftolozane
tazobactam
cefiderocol

36
Q
  1. Carbapenems. Monobactams. Beta-lactamase inhibitors.
A

imipenem
cilastatin
meropenem
clavulanate
tazobactam
vaborbactam
Aztreonam

37
Q
  1. Chloramphenicol. Polymyxins. Antifolate drugs
A

chloramphenicol
colistin
sulfamethoxazole +trimethoprim
proguanil

38
Q
  1. Tetracyclines and glycylcyclines
A

doxycycline
tigecycline

39
Q
  1. Aminoglycosides
A

tobramycin
Gentamicin
Netilmicin
streptomycin
Amikacin
Kanamycin
neomycin

40
Q
  1. Quinolones and fluoroquinolones
A

norfloxacin
ciprofloxacin ,
ofloxacin
levofloxacin
moxifloxacin

41
Q
  1. Macrolides. Pleuromutilins
A

clarithromycin
roxithromycin
azithromycin
lefamulin

42
Q
  1. Clindamycin. Streptogramins. Oxazolidinones. Fusidans.
A

clindamycin
quinupristin/dalfopristin
linezolid
fusidic acid

43
Q
  1. Glycopeptides. Lipopeptides. Bacitracin. Mupirocin.
A

Oritavancin
Vancomycin
Teicoplanin
bacitracin
mupirocin
Daptomycin

44
Q
  1. Metronidazole. Fidaxomycine. Rifaximin. Nitrofurantoin. Phosphomycine.
A

metronidazole
fidaxomicin
rifaximin
nitrofurantoin
fosfomycin

45
Q
  1. Drugs influencing blood coagulation I: Antiplatelet agents. Fibrinolytic drugs. Drugs inhibiting
    bleeding
A

acetylsalicylic acid
clopidogrel
prasugrel
ticagrelor
abciximab
alteplase
reteplase
epsilon-amino-caproic acid
vitamin K
epinephrine
fibrin foam

46
Q
  1. Drugs influencing blood coagulation II: Anticoagulant drugs
A

heparin
dalteparin
warfarin
dabigatran-etexilate
rivaroxaban
fondaparinux

47
Q
  1. Agents used in anemias
A

iron hydroxide polymaltose
folic acid
vitamin B12
epoetin-alfa
filgrastim

48
Q
  1. Positiv inotropic drugs
A

digoxin
digitoxin
milrinone
levosimendan
dobutamine

49
Q
  1. Drugs influencing cardiac electrophysiology.
A

lidocaine
propafenone
esmolol
amiodarone
sotalol
verapamil
adenosine
digoxin
Mg++

50
Q
  1. Drugs acting on the renin-angiotensin-aldosterone-system (RAAS)
A

enalapril
perindopril
ramipril
losartan
valsartan
valsartan + sacubitril
irbesartan
spironolactone
eplerenon
captopril

51
Q
  1. Ca++
    -channel blockers and other vasodilators
A

amlodipine
felodipine
nifedipine
nimodipine
verapamil
dihydralazine
bozentan
sildenafil

52
Q
  1. Drugs influencing the oxygen demand and oxygen supply of the heart. Drugs improving
    microcirculation.
A

nitroglycerin
isosorbid-mononitrate
trimetazidine
ivabradine
beta-blockers and Ca-channel blockers
Vinpocetin
Nicergoline
Pentoxifylline
Ca-dobesilate
Cinnarizine

53
Q
  1. Drugs affecting lipid metabolism.
A

simvastatin
atorvastatin
rosuvastatin
ezetimib
fenofibrate
colesevelam

54
Q
  1. Potassium excreting (wasting) diuretics
A

acetazolamide
hydrochlorothiazide
indapamide
furosemide
etacrynic acid

55
Q
  1. Potassium sparing diuretics, ADH antagonists, osmotic diuretics
A

spironolactone
eplerenone
amiloride
tolvaptan
mannitol
glycerol

56
Q
  1. Glucocorticoids for oral and parenteral use
A

hydrocortisone
prednisolone
methylprednisolone
dexamethasone
triamcinolone

57
Q
  1. Mineralocorticoids. Topically applied glucocorticoids. Adrenocortical antagonists, inhibitors of
    corticosteroid synthesis.
A

fludrocortisone
fluocinolone
mometazone
budesonide
fluticasone
metyrapone

58
Q
  1. Androgens, anabolic steroids, antiandrogens. Agents affecting the sexual activity
A

testosterone-undecanoate
bicalutamide
finasteride
goserelin
degarelix
sildenafil
nandrolone

59
Q
  1. Estrogens and antiestrogens
A

ethinylestradiol
estradiol
clomifen
tamoxifen
raloxifen
anastrozole
goserelin
degarelix

60
Q
  1. Progestins and antiprogestins. Contraceptives
A

medroxyprogesterone-acetate
drospirenone
norethisterone
levonorgestrel
desogestrel
cyproterone-acetate
mifepristone
ulipristal acetate
ethinylestradiol + levonorgestrel

61
Q
  1. Thyroid and antithyroid drugs. Pituitary hormones. Hypothalamic hormones, hormonanalogs and
    antagonists.
A

levothyroxin
thiamazole
propylthiouracil
iodine
octreotide
bromocriptine
desmopressin
oxytocin

62
Q
  1. Pancreatic hormones and parenterally applied antidiabetic drugs.
A

regular insulin
lispro insulin
aspart insulin
glargine insulin
isophan (NPH)-insulin
liraglutide

63
Q
  1. Oral antidiabetics.
A

metformin
dapagliflozin
vildagliptin
acarbose
glipizide
glimepiride
repaglinide

64
Q
  1. Agents affecting bone mineral homeostasis (calcium, vitamin D, parathyroid hormone, calcitonin,
    etc.).
A

cholecalciferol
teriparatide
raloxifen
zoledronate
alendronate
denosumab

65
Q
  1. Selective 2-stimulants and other bronchodilators.
A

salbutamol
terbutaline
fenoterol
salmeterol
formoterol
ipratropium
tiotropium
theophylline

66
Q
  1. Antiinflammatory agents inhibiting bronchial inflammatory processes. Antitussive agents and
    expectorants
A

prednisolone
methylprednisolone
fluticazone
budesonide
montelukast
omalizumab
(dihydro-)codein
butamirate
prenoxdiazine
acetylcysteine
bromhexine, ambroxol

67
Q
  1. Drugs influencing gastric acid secretion, protective drugs of gastric mucosa
A

(es)omeprazole
pantoprazole
famotidine
MgO magnesium oxide
Al2(OH)3 aluminum-hydroxide

68
Q
  1. Antiemetic drugs. Prokinetic agents.
A

dimenhydrinate
droperidol
metoclopramide
ondansetron
palonosetron
(fos)aprepitant
some cannabinoids

69
Q
  1. Drugs used in constipation (laxatives) and diarrhea. Drugs promoting digestion. Pharmacology of liver
    and biliary tract
A

plant fibers
magnesium-oxide
lactulose
paraffin oil
sennoside
bisacodyl
diphenoxylate
loperamide
active charcoal, kaoline
ursodeoxycholic acid
acetylcysteine
silymarin (its active compound: silibinine)

70
Q
  1. Immunopharmacology I. (cytotoxic agents).
A

cyclophosphamide
methotrexate
leflunomide
azathioprine
mycophenolate-mofetil

71
Q
  1. Immunopharmacology II. (Inhibitors of cytokine gene expression, 5-ASA derivatives)
A

cyclosporin A
tacrolimus
sirolimus
tofacitinib
sulfasalazine

72
Q
  1. Immunopharmacology III. (Antibodies and fusion proteins)
A

ATG (antithymocyte-globulin)
rituximab
infliximab
adalimumab
tocilizumab
ustekinumab
natalizumab
dupilumab
abatacept

73
Q
  1. Drugs used in cancer treatment I (antimetabolites)
A

5-fluorouracil
capecitabine
cytarabine
6-merkaptopurine
methotrexate
pemetrexed

74
Q
  1. Drugs used in cancer treatment II (cytotoxic agents targeting DNA)
A

cyclophosphamide
dacarbazine
temozolomide
cisplatin
oxaliplatin
dactinomycin
bleomycin

75
Q
  1. Drugs used in cancer treatment III (Topisomerase inhibitors. Inhibitors of mitotic spindle)
A

irinotecan
etoposide
doxorubicin
vincristine
docetaxel

76
Q
  1. Drugs used in cancer treatment IV. (Hormonal agents)
A

tamoxifen
anastrozole
goserelin
degarelix
bicalutamide
prednisolone
octreotide

77
Q
  1. Drugs used in cancer treatment V. (Small molecule signal transduction inhibitors. Retinoids)
A

imatinib
gefitinib
erlotinib
lapatinib
sunitinib
ibrutinib
crizotinib
bortezomib
dabrafenib+ trametinib
everolimus
tretinoin

78
Q
  1. Drugs used in cancer treatment VI. (Large molecule signal transduction inhibitors. Immunostimulant
    anticancer drugs.)
A

trastuzumab (-emtansine)
panitumumab
rituximab
bevacizumab
alfa-interferon
aldesleukin
pembrolizumab

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