Dr Moks Lectures Flashcards

1
Q

What is a solution

A
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2
Q

What is an ointment

A
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3
Q

What is a colloid

A
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4
Q

What does intra venous mean

A
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5
Q

What does topical mean

A
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6
Q

What does a surfactant do

A

Reduces surface tension

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7
Q

What is a micelle

A
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8
Q

How big is a colloidal system

A

<1 micrometres

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9
Q

Do colloids scatter Iight?

A

Yes, this is known as the Tyndall effect

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10
Q

What is the brown Ian motion?

A

Liquid molecules are always in motion, under a microscope you can observe that the larger colloidal particles are kept in suspension because of this constant bombardment

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11
Q

What is adsportion?

A

Molecules STICK to the surface of an adsorbent, chemical associated to surface of the agent

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12
Q

How would you separate a colloidal system?

A

By dialysis - use of a semi-permeable membrane with small enough pores to allow only the ions and the continuous phase to move through, leaving the colloids in the tube

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13
Q

How would you desperate charged colloidal particles?

A

With use of electrophoresis

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14
Q

What are the types of colloids (physically)

A

Gas in liquid or solid Liquid in gas, liquid or solid Solid in gas, liquid or solid

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15
Q

What are the types of colloids? (Ionically)

A

Lyophobic - solvent hating (e.g hydrophobic if continuous phase is H2O). Lyophilic - solvent liking (e.g hydrophilic if H2O)

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16
Q

What are foams?

A

Gases in liquids/solids

17
Q

How do you reduce foam?

A

Using defoamers/ anti foaming agents. These act as small droplets which displace surfactants which stabilise thin films.

18
Q

What are the three types of degradation of drugs

A

Chemical
Physical
Microbial

19
Q

What are the four types of chemical degradation?

A

Hydrolysis
Oxidation
Photodegredation
Polymerisation
Dimerisation

20
Q

How would you reduce hydrolysis of a drug?

A

Surfactants
Complexation

21
Q

How would you circumvent auto-oxidation?

A

Exclude oxygen
Add antioxidants

22
Q

How would you reduce photodegredation

A

Filter light with amber glass or coating for tablets
Store in dark areas