Dr. Kruse's Pharm NMJ lecture ADDITION

Question 1

N(m):

main location, action, response

Answer 1

skeletal muscle (postjunctional), excitatory/contraction, increased cation permeability

Question 2

N(m) agonists

Answer 2

nicotine and ACh and Succinylcholine

Question 3

N(m): antagonists

Answer 3

Atracurium
Vecuronium
d-tubocurarine
pancuronium

Question 4

N(N):

main location, action, response

Answer 4

Autonomic ganglia, adrenal medulla

Excitatory, depolarization

increased cation permeability

Question 5

N(N) agonist

Answer 5

ACh

Nicotine

Question 6

N(N) antagonists

Answer 6

mecamylamine

Question 7

Central neuronal:

location, action, response

Answer 7

CNS

Excitatory,
Pre-junctional control of ACh release

increased cation permeability

Question 8

Central neuronal agonist

Answer 8

Cytisine

Anatoxin A

Question 9

Central neuronal antagonist

Answer 9

Mecamylamine