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AS - N926 Pharmacology > Dosages > Flashcards

Dosages Flashcards

1
Q

Thiopental

A

Induction 2.5-5mg/kg

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2
Q

Methohexital

A

ECT ↓ seizure threshold
Induction 1-2mg/kg
Infusion 50-150mcg/kg/min

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3
Q

Midazolam (Versed)

A

IV 0.02-0.04mg/kg
PO 0.4-0.8mg/kg
Sedation post-op 0.5-4mg load
Infusion 1-7mg/hr

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4
Q

Diazepam (Valium)

A

Induction 0.5-1mg/kg

Anticonvulsant 0.1mg/kg

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5
Q

Lorazepam (Ativan)

A

IV 1-4mg

PO 50mcg/kg

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6
Q

Flumazenil

A

Initial 0.2mg
0.1mg Q1min
0.5-1mg to reverse effects
> 5mg no response another issue

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7
Q

Propofol

A

Induction 1.5-2.5mg/kg
MAC sedation 25-100mcg/kg/min (1.5-6mg/kg)
Anesthesia maintenance TIVA 100-300mcg/kg/min
Antiemetic 10-15mg then 10mcg/kg/min
Antipruritic 10mg
Anticonvulsant 1mg/kg

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8
Q

Etomidate

A

Induction 0.2-0.4mg/kg

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9
Q

Ketamine

A 
Induction 1-2.5mgkg IV
IM 4-8mg/kg
PO 10mg/kg 
Analgesic 0.2-0.5mg/kg (somatic > visceral)
0.5-1mg/kg prior to surgical incision
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10
Q

Dexmedetomidine (Precedex)

A

TIVA 0.5-1mcg/kg bolus over 15min
Infusion 0.2-0.7mcg/kg/hr
0.5-2mcg/kg
Bolus 4mcg up to 16-20mcg

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11
Q

Scopolamine

A

IV/IM 0.3-0.5mg

Antiemetic 1.5mg patch

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12
Q

Physostigmine

A

Reversal 15-60mcg/kg IV

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13
Q

Morphine

A

IV 0.1-0.2mg/kg

IM 4mg

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14
Q

Codeine

A

PO 15mg
60mg = 650mg ASA
IM 120mg = 10mg Morphine

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15
Q

Meperidine

A

Anti-shivering

12.5mg

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16
Q

Fentanyl

A 
75-125x more potent than Morphine
Block sympathetic stim 1-3mcg/kg (prior to anesthesia induction)
Analgesia 1-3mcg/kg
Surgical as sole anesthetic 50-150mcg/kg
Peds PO 15-20mcg/kg (pre-op sedation)
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17
Q

Sufentanil

A

5-10x more potent than Fentanyl
Analgesia 0.1-0.4mcg/kg
*Chest wall rigidity

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18
Q

Alfentanil

A

Less potent than Fentanyl
Blunt stimulation 15mcg/kg (laryngoscopy)
Catecholamine response 30mcg/kg (noxious stim)
Induction 150-300mcg/kg (produces unconscious)
Combination w/ inhalation anesthetic 15-150mcg/kg/hr

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19
Q

Remifentanil

A

Induction 0.25-1 or 1-3mcg/kg bolus prior to induction agent
Analgesia TIVA 0.05-0.2 or 0.1-0.3mcg/kg/min
Sedation 0.05-0.1mcg/kg/min in combination w/ 2mg Midazolam

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20
Q

Hydromorphone (Dilaudid)

A

Acute post-operative pain
5x more potent than Morphine
0.5-1mg

21
Q

Methadone

A

IV 20mg
Substitute Morphine 1/4 dosage
Post-op analgesia >24hrs

22
Q

Tramadol

A

Less potent than Morphine

23
Q

Nalbuphine

A

10mg IV/IM Q3-6H
Maximum single dose 20mg
Induction 0.3-3mg/kg
Maintenance 0.25-0.5mg/kg

24
Q

Buprenorphine

A

Potent analgesic

0.3mg IM = 10mg Morphine

25
Q

Naloxone

A

IV 1-4mcg/kg

PCA 5mcg/kg/hr fix respiratory depression w/out affecting analgesia

26
Q

Nalmefene

A

IV 15-25mcg

MAX 1mcg/kg

27
Q

Ketorolac (Toradol)

A

IV/IM 15mg Q6H

Avoid in renal compromise

28
Q

Celecoxib (Celebrex)

A

400mg PO pre-op

200mg BID x5 days post-op

29
Q

Acetaminophen (Tylenol)

A

PO 325-650mg Q4-6H
IV 1,000mg Q6H
MAX 4,000mg/24H (2,000mg chronic alcoholics)

30
Q

Gabapentin

A

Pre-op 1,200mg 1-2hr prior surgery

PO 600mg Q8H x 14 days

31
Q

Lidocaine

A

Induction 1-1.5mg/kg
Bolus 1.5mg/kg
Infusion 1-2mg/kg/hr

32
Q

Magnesium Sulfate

A

Bolus 30-50mg/kg

Infusion 10mg/kg/hr or 1-2G/hr

33
Q

Succinylcholine

A

Intubating dose 1mg/kg

34
Q

Atracurium

A

Intubating dose 0.5mg/kg

35
Q

Cisatracurium

A

Intubating dose 0.1mg/kg

36
Q

Mivacurium

A

Intubating dose 0.15mg/kg

37
Q

Pancuronium

A

Intubating dose 0.08mg/kg

38
Q

Vecuronium

A

Potent & slow onset

Intubating dose 0.1mg/kg

39
Q

Rocuronium

A

Intubating dose 0.6mg/kg

40
Q

Neostigmine

A

40-80mcg/kg
Maximum dose 6mg
NMBD reversal dose based on % block
Assess twitches number, strength, and fade

41
Q

Edrophonium

A

1-1.5mg/kg

42
Q

Glycopyrrolate

A

5-10mcg/kg
200mcg per 1mg Neostigmine OR
0.4mg per 2mg Neostigmine

43
Q

Atropine

A

7-10mcg/kg OR 0.01mg/kg

44
Q

Sugammadex

A

Dose based on TOF
TOF >2 = 2mg/kg
1-2 = 4mg/kg
0 = 8-16mg/kg

45
Q

Aprepitant

A

PO 40-80mg

High risk non-pregnant patients

46
Q

Metoclopramide

A

0.1-0.25mg/kg
Chemotherapy 1-2mg/kg
IV slow push

47
Q

Promethazine

A

12.5-25mg

IM route preferred

48
Q

Dexamethasone

A

4-10mg

Admin after induction

49
Q

Ondansetron

A

4mg up to 16mg

Admin 30min prior to surgery end

AS - N926 Pharmacology (18 decks)

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