Dosages Flashcards
Thiopental
Induction 2.5-5mg/kg
Methohexital
ECT ↓ seizure threshold
Induction 1-2mg/kg
Infusion 50-150mcg/kg/min
Midazolam (Versed)
IV 0.02-0.04mg/kg
PO 0.4-0.8mg/kg
Sedation post-op 0.5-4mg load
Infusion 1-7mg/hr
Diazepam (Valium)
Induction 0.5-1mg/kg
Anticonvulsant 0.1mg/kg
Lorazepam (Ativan)
IV 1-4mg
PO 50mcg/kg
Flumazenil
Initial 0.2mg
0.1mg Q1min
0.5-1mg to reverse effects
> 5mg no response another issue
Propofol
Induction 1.5-2.5mg/kg
MAC sedation 25-100mcg/kg/min (1.5-6mg/kg)
Anesthesia maintenance TIVA 100-300mcg/kg/min
Antiemetic 10-15mg then 10mcg/kg/min
Antipruritic 10mg
Anticonvulsant 1mg/kg
Etomidate
Induction 0.2-0.4mg/kg
Ketamine
Induction 1-2.5mgkg IV IM 4-8mg/kg PO 10mg/kg Analgesic 0.2-0.5mg/kg (somatic > visceral) 0.5-1mg/kg prior to surgical incision
Dexmedetomidine (Precedex)
TIVA 0.5-1mcg/kg bolus over 15min
Infusion 0.2-0.7mcg/kg/hr
0.5-2mcg/kg
Bolus 4mcg up to 16-20mcg
Scopolamine
IV/IM 0.3-0.5mg
Antiemetic 1.5mg patch
Physostigmine
Reversal 15-60mcg/kg IV
Morphine
IV 0.1-0.2mg/kg
IM 4mg
Codeine
PO 15mg
60mg = 650mg ASA
IM 120mg = 10mg Morphine
Meperidine
Anti-shivering
12.5mg
Fentanyl
75-125x more potent than Morphine Block sympathetic stim 1-3mcg/kg (prior to anesthesia induction) Analgesia 1-3mcg/kg Surgical as sole anesthetic 50-150mcg/kg Peds PO 15-20mcg/kg (pre-op sedation)
Sufentanil
5-10x more potent than Fentanyl
Analgesia 0.1-0.4mcg/kg
*Chest wall rigidity
Alfentanil
Less potent than Fentanyl
Blunt stimulation 15mcg/kg (laryngoscopy)
Catecholamine response 30mcg/kg (noxious stim)
Induction 150-300mcg/kg (produces unconscious)
Combination w/ inhalation anesthetic 15-150mcg/kg/hr
Remifentanil
Induction 0.25-1 or 1-3mcg/kg bolus prior to induction agent
Analgesia TIVA 0.05-0.2 or 0.1-0.3mcg/kg/min
Sedation 0.05-0.1mcg/kg/min in combination w/ 2mg Midazolam
Hydromorphone (Dilaudid)
Acute post-operative pain
5x more potent than Morphine
0.5-1mg
Methadone
IV 20mg
Substitute Morphine 1/4 dosage
Post-op analgesia >24hrs
Tramadol
Less potent than Morphine
Nalbuphine
10mg IV/IM Q3-6H
Maximum single dose 20mg
Induction 0.3-3mg/kg
Maintenance 0.25-0.5mg/kg
Buprenorphine
Potent analgesic
0.3mg IM = 10mg Morphine
Naloxone
IV 1-4mcg/kg
PCA 5mcg/kg/hr fix respiratory depression w/out affecting analgesia
Nalmefene
IV 15-25mcg
MAX 1mcg/kg
Ketorolac (Toradol)
IV/IM 15mg Q6H
Avoid in renal compromise
Celecoxib (Celebrex)
400mg PO pre-op
200mg BID x5 days post-op
Acetaminophen (Tylenol)
PO 325-650mg Q4-6H
IV 1,000mg Q6H
MAX 4,000mg/24H (2,000mg chronic alcoholics)
Gabapentin
Pre-op 1,200mg 1-2hr prior surgery
PO 600mg Q8H x 14 days
Lidocaine
Induction 1-1.5mg/kg
Bolus 1.5mg/kg
Infusion 1-2mg/kg/hr
Magnesium Sulfate
Bolus 30-50mg/kg
Infusion 10mg/kg/hr or 1-2G/hr
Succinylcholine
Intubating dose 1mg/kg
Atracurium
Intubating dose 0.5mg/kg
Cisatracurium
Intubating dose 0.1mg/kg
Mivacurium
Intubating dose 0.15mg/kg
Pancuronium
Intubating dose 0.08mg/kg
Vecuronium
Potent & slow onset
Intubating dose 0.1mg/kg
Rocuronium
Intubating dose 0.6mg/kg
Neostigmine
40-80mcg/kg
Maximum dose 6mg
NMBD reversal dose based on % block
Assess twitches number, strength, and fade
Edrophonium
1-1.5mg/kg
Glycopyrrolate
5-10mcg/kg
200mcg per 1mg Neostigmine OR
0.4mg per 2mg Neostigmine
Atropine
7-10mcg/kg OR 0.01mg/kg
Sugammadex
Dose based on TOF
TOF >2 = 2mg/kg
1-2 = 4mg/kg
0 = 8-16mg/kg
Aprepitant
PO 40-80mg
High risk non-pregnant patients
Metoclopramide
0.1-0.25mg/kg
Chemotherapy 1-2mg/kg
IV slow push
Promethazine
12.5-25mg
IM route preferred
Dexamethasone
4-10mg
Admin after induction
Ondansetron
4mg up to 16mg
Admin 30min prior to surgery end